Non-invasive diagnosis of H pylori infection: Evaluation of serological tests with and without current infection marker CIM

Abstract

CONCLUSION:Immunoblot with CIM had the best performance. ICT with CIM was found to be more specific and accurate than the conventional ELISA and may be useful for non-invasive diagnosis of H pylori infection.

Non-Invasive Diagnosis of Helicobacter pylori: Evaluation of Two Enzyme Immunoassays, Testing Serum IgG and IgA Response in the Anand District of Central Gujarat, India

“…The IgG, evaluated in our study, had a sensitivity and negative predictive values of 100% respectively, which is almost in accordance with other studies [11][12][13] [Table /Fig-4]. The high sensitivity observed permits the safe use of the test in epidemiologic surveys.…”

Comparative Evaluation of RUT, PCR and ELISA Tests for Detection of Infection with Cytotoxigenic H. pylori

“…26 ELISA is safe, not influenced by sampling errors and less of a burden for patients. 34 In our study, ELISA yielded 90.20 % sensitivity and 61.11% specificity, respectively. Compared to PCR, ELISA presented higher sensitivity and lower specificity.…”

Correlation Between Expression of the Cancer/Testis Antigen KK-LC-1 and Helicobacter pylori Infection in Gastric Cancer

“…Additionally, it might be possible that the cause of cancerization could be clarified by analyzing CTA expression. We assessed H. pylori infection using anti-H. pylori IgG in serum because this assay gives an accurate reflection of the infection status of the patient (11). Following the manufacture's protocol, a reading below 20 U/ml was considered negative for H. pylori infection.…”

“…There are many reports showing that H. pylori infection can be accurately measured by detecting anti-H. pylori antibodies in serum (11). We evaluated H. pylori infection using serum from the 25 gastric patients with cancer.…”