Diagnosis of major salivary gland tuberculosis: Experience of eight cases and review of the literature

Abstract

The parotid and submandibular glands were involved in 5 (62.5%) and 3 cases (37.5%), respectively. Neck CT demonstrated typical findings of salivary gland tuberculosis in 3 patients (37.5%). Fine-needle aspiration cytology revealed chronic inflammation in 6/7 patients (85.7%), 2 of whom (33.3%) showed caseous necrosis, strongly suggesting tuberculosis. Five of the 8 patients (62.5%) required resection of the affected gland and 3 (37.5%) received open biopsy. PCR was performed in half of the cases and was affirmative in every case. No significant differences were found between the surgically resected and non-resected groups in terms of treatment results or morbidity. All patients received anti-tuberculous chemotherapy for 8-12 months, with no disease recurrence.

Tuberculosis de cabeza y cuello: estudio retrospectivo de 6 años

“…La forma de presentación en caso de ser una Tb primaria a este nivel suele ser en forma de sialoadenitis supurativa o simulando una lesión tumoral crónica. Las formas secundarias suelen ser aquellas asociadas a una Tb sistémica, más frecuentemente pulmonar 31 .…”

Fluorine-18-fluorodeoxyglucose PET/CT rare finding of a unique multiorgan involvement of Wegener's granulomatosis

“…The clinical appearance of WG involvement of the salivary glands (especially the parotid and submandibular glands) varies and it might be difficult to differentiate the appearances of WG from other differential diagnoses, such as malignant neoplasm, abscess, sarcoidosis, tuberculosis and infection based on imaging evaluation including 18F-FDG PET/CT scan [13][14][15][16][17].…”

Tuberculose primaire de la glande parotide : à propos d’un cas

“…Une radiographie pulmonaire doit systématiquement être demandée, afin de rechercher un éventuel foyer primitif. Sur le plan biologique, on retrouve généralement un syndrome inflammatoire et l'intradermoréaction à la tuberculine n' est pas toujours positive [2][3][4][5]. Ainsi, aucun élément clinique, radiologique et biologique ne permet d'affirmer le diagnostic de tuberculose parotidienne.…”

“…Au niveau de la sphère ORL, l'atteinte ganglionnaire est la plus fréquente. La localisation isolée de la tuberculose au niveau des glandes salivaires, et notamment de la parotide, est extrêmement rare [1,2]. La présentation clinique est polymorphe et non spécifique.…”