2016
DOI: 10.1007/s11011-016-9878-y
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Diagnosis of minimal hepatic encephalopathy in a tertiary care center from eastern Romania: validation of the psychometric hepatic encephalopathy score (PHES)

Abstract: The psychometric hepatic encephalopathy score (PHES) is frequently used as a "gold standard" for the diagnosis of minimal hepatic encephalopathy (MHE). In Romania, there are currently no widely available tests for the detection of MHE. In this study we aimed to standardize the PHES in a healthy Romanian population and to estimate the prevalence of MHE in a group of Romanian patients with liver cirrhosis. A total of 260 healthy volunteers and 106 patients with liver cirrhosis were included in the study. The fiv… Show more

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Cited by 20 publications
(18 citation statements)
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“…Mild defects of MHE cognitive function can sometimes be detected through specific methods such as mental assessment scales or neuropsychiatric testing. Currently, a worldwide consensus on the diagnostic criterion for MHE is absent, and the diagnosis of MHE is difficult . It is common to use more than two sensitive neuropsychological tests.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Mild defects of MHE cognitive function can sometimes be detected through specific methods such as mental assessment scales or neuropsychiatric testing. Currently, a worldwide consensus on the diagnostic criterion for MHE is absent, and the diagnosis of MHE is difficult . It is common to use more than two sensitive neuropsychological tests.…”
Section: Discussionmentioning
confidence: 99%
“…Currently, a worldwide consensus on the diagnostic criterion for MHE is absent, and the diagnosis of MHE is difficult. 30,31 It is common to use more than two sensitive neuropsychological tests. This study used NCT-A to preliminarily screen the patients with hepatitis B cirrhosis, which revealed 62.76% MHE patients (214 cases).…”
Section: Sleep Quality In Hepatitis B Cirrhosis Patients E279mentioning
confidence: 99%
“…Approximately 30 million people around Europe suffer from chronic liver disease, while the death rate from liver cirrhosis covers 1,8%, according to WHO data [1,2]. Among the causes of chronic liver disease, non alcoholic fatty liver disease (NAFLD) has beome of major interest worldwide, considering it represents an entity with increasing prevalence and -due to the associated conditions-leads to increased risk of developing cirrhosis, liver cancer, type 2 diabetes melitus, atherosclerosis and related cardiovascular disease [3][4][5][6][7][8][9][10]. The prevalence of NAFLD in Europe is estimated between 20-44%, iar for diabetic patients it reaches worrying levels: 42.6-69.5% [1][2][3]11].…”
Section: Syndrome Liver Fibrosismentioning
confidence: 99%
“…Keywords: LAIs substances, olanzapine pamoate, risperidone, aripiprazole monohydrate, oral antipsychotic, relapse Nonadherence rates in patients with schizophrenia are known to be high in comparison to patients with other diseases [1][2][3]. Estimates in the literature range between 40 and 50%, but can be as high as 89% [4].…”
mentioning
confidence: 99%
“…Risperidone, as well as its active metabolite, 9-hydroxirisperidone, is a potent antagonist of the 5-hydroxitryptamine type IIA and of type II dopamine receptors, and with a low affinity for muscharinic and β adrenergic receptors [3,5]. Risperidone formula is 3-…”
mentioning
confidence: 99%