Diagnostic role of cardiopulmonary exercise testing in patients with sarcoidosis

Postnikova, Larisa; Гудим, А. Л.; Костров, В. А.; Доровской, И. А.; Соодаева, С. А.; Popova, N A

doi:10.18093/0869-0189-2018-28-6-736-745

Pulʹmonologiâ (Mosk.)

2019

DOI: 10.18093/0869-0189-2018-28-6-736-745

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Diagnostic role of cardiopulmonary exercise testing in patients with sarcoidosis

Larisa Postnikova¹,

А. Л. Гудим²,

В. А. Костров³

et al.

Abstract: Государственное бюджетное учреждение здравоохранения Нижегородской области «Городская клиническая больница № 38 Нижегородского района г. Нижнего Новгорода», Россия, 603000, Нижний Новгород, ул. Чернышевского, 22; 2-Федеральное государственное бюджетное учреждение «Научно-исследовательский институт пульмонологии» Федерального медико-биологического агентства: 115682, Москва, Ореховый бульвар, 28; 3-Областное бюджетное учреждение здравоохранения «Суджанская центральная районная больница» Комитета здравоохранения … Show more

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2023

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Cited by 2 publications

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Cardiopulmonary Test As A Component in the Diagnostic Algorithm for Heart Failure with Preserved Left Ventricular Ejection Fraction in Patients with Atrial Fibrillation

Zotov

Gorbacheva²,

Mandel³

et al. 2023

Journal of Clinical Practice

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Objective: to evaluate the role of cardiopulmonary test in the diagnosis of heart failure with preserved ejection fraction in patients with atrial fibrillation. Material and Methods: 138 patients with atrial fibrillation were included in our study. Using HFA-PEFF algorithm (algorithm for diagnosis of heart failure with preserved left ventricular ejection fraction) all patients were initially divided into 3 groups: low probability of heart failure - 23 patients, intermediate probability - 96 and high probability - 19 patients. The stress-test allowed to precisely assess of patients at intermediate risk and finally form the groups: Group 1 without heart failure, 85 patients (61.6%); Group 2 patients with heart failure and preserved ejection fraction, 53 patients (38.4%). The next diagnostic stage was cardiopulmonary test. Results: during CPT, the maximum anaerobic exercise threshold was 6.8 and 4.85 METS for the first and second groups, respectively (p0.001), reflecting lower exercise tolerance in the second group of patients. Analysis of variance (ANOVA) demonstrated a statistically significant increase in pro-BNP levels with a decrease in peak VO2 (p0.001). Also, analysis of variance demonstrated a significant statistical difference with respect to systolic pulmonary artery pressure in the subgroups with severely, moderately reduced oxygen consumption and in the group with normal peak VO2 (p=0.01). ROC analysis determined a peak VO2 of 20 ml/kg/min, above which the HFA-PEFF algorithm was unlikely to detect heart failure (AUC 0.73; confidence interval 0.65-0.82; p=0.043; sensitivity 85%; specificity 51%). Conclusion: Cardiopulmonary test is a reliable instrumental noninvasive method of investigation in the diagnosis of heart failure with preserved ejection fraction. Keywords: atrial fibrillation; chronic heart failure; cardiopulmonary test; ergospirometry

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Cardiopulmonary Test As A Component in the Diagnostic Algorithm for Heart Failure with Preserved Left Ventricular Ejection Fraction in Patients with Atrial Fibrillation

Zotov

Gorbacheva²,

Mandel³

et al. 2023

Journal of Clinical Practice

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The relevance of the use of cardiopulmonary exercise testing (CPET) in elderly and senile patients

Tkacheva

Kotovskaya

Runikhina

et al. 2023

Rossiiskii zhurnal geriatricheskoi meditsiny

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Cardiopulmonary exercise testing is a study that provides both prognostic and diagnostic information about the state of the cardiovascular, respiratory systems and metabolic processes allowing us to determine how these systems contribute to a decrease in exercise tolerance. A large number of clinical studies using this method have shown its safety and diagnostic value. However, due to insufficient education among doctors and little experience, CPNT is currently not widely used in diagnostics, especially in the geriatrics. This review of available literature over the last 10 years is devoted to the relevance of the use of cardiopulmonary exercise testing in older and oldest older patients, the essence and methodology of the study, possible changes in indicators in patients with frailty, chronic heart failure, and diseases of the bronchopulmonary system.

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Diagnostic role of cardiopulmonary exercise testing in patients with sarcoidosis

Cited by 2 publications

References 20 publications

Cardiopulmonary Test As A Component in the Diagnostic Algorithm for Heart Failure with Preserved Left Ventricular Ejection Fraction in Patients with Atrial Fibrillation

Cardiopulmonary Test As A Component in the Diagnostic Algorithm for Heart Failure with Preserved Left Ventricular Ejection Fraction in Patients with Atrial Fibrillation

The relevance of the use of cardiopulmonary exercise testing (CPET) in elderly and senile patients

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