Diet and lead toxicity

Moore, M. R.

doi:10.1079/pns19790038

Cited by 30 publications

(6 citation statements)

References 40 publications

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“…A high protein intake has been associated with increased calcium excretion (see chapter 1.2.3.2 "Acids"), and excess sodium intake may increase calcium excretion and decrease BMD [56]. A low calcium status could also cause increased uptake of heavy metals such as lead [57,58], and body burden of lead has been reported to be negatively correlated with calcium in blood [59].…”

Section: Established Risk Factorsmentioning

confidence: 99%

Is the quality of drinking water a risk factor for self-reported forearm fractures? Cohort of Norway

et al. 2012

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Section: Established Risk Factorsmentioning

confidence: 99%

Is the quality of drinking water a risk factor for self-reported forearm fractures? Cohort of Norway

et al. 2012

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“…Because cadmium and lead are both bivalent cations, their respective metabolisms show some similarities and differences in the body. Their absorption in the digestive tract is low, but lead absorption (>10%) is greater than cadmium absorption (about 5%) in adults, and it is five to eight times greater in children than in adults (Satarug and Moore 2004;Moore 1979). After absorption into the body, cadmium and lead are distributed throughout most tissues; however, cadmium is stored mainly in the kidney cortex and liver, and lead accumulates in bone.…”

Section: Discussionmentioning

confidence: 97%

Strong positive association of traditional Asian-style diets with blood cadmium and lead levels in the Korean adult population

Park

Lee

2013

International Journal of Environmental Health Research

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Blood lead and cadmium levels are more than twofold to fivefold higher in the Korean population compared to that of the USA. This may be related to the foods consumed. We examined which food categories are related to blood lead and cadmium levels in the Korean adult population using the 2008-2010 Korean National Health and Nutrition Examination Survey (n = 5504). High and moderate consumption of bread and crackers, potatoes, meat and meat products, milk and dairy products, and pizza and hamburger resulted in significantly lower odds ratios for blood lead levels than their low consumption. However, consumption of salted fish, white fish, green vegetables, white and yellow vegetables, coffee, and alcohol resulted in significantly higher odds ratios of blood lead and cadmium. In conclusion, the typical Asian diet based on rice, fish, vegetables, regular coffee, and alcoholic drinks may be associated with higher blood cadmium and lead levels. This study suggests that lead and cadmium contents should be monitored and controlled in agricultural products to reduce health risks from heavy metals.

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“…T h e processes involved in the passage of ingested lead from the gut lumen to incorporation in t h e body structure are not well understood. Measurements have shown that retention of lead varies inversely with dietary calcium content (7) although a residual degree of lead absorption remains unaffected by calcium concentration (8). This suggests two separate processes are involved.…”

Section: E C H a N I S M O F A B S O R P T I O Nmentioning

confidence: 99%

Theoretical Model of Gastrointestinal Absorption of Lead

1984

J Clin Pharm Ther

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SUMMARY A theoretical model is presented which is used to explain gastrointestinal absorption of ingested lead from use of traditional medicines. Dissolution processes are discussed and the relative contributions of pore and passive diffusion through the intestinal epithelium for the resulting species examined. The determination of the rate of absorption is described in terms of a mathematical three‐compartment system and effects of particle size are considered by reference to the Noyes‐Whitney dissolution rate law.

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Diet and lead toxicity

Cited by 30 publications

References 40 publications

Is the quality of drinking water a risk factor for self-reported forearm fractures? Cohort of Norway

Is the quality of drinking water a risk factor for self-reported forearm fractures? Cohort of Norway

Strong positive association of traditional Asian-style diets with blood cadmium and lead levels in the Korean adult population

Theoretical Model of Gastrointestinal Absorption of Lead

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