Dietary interventions for preventing complications in idiopathic hypercalciuria

Escribano, Joaquín; Balaguer, Albert; Figuls, Marta Roqué i; Feliu, Albert; Ferré, Natàlia

doi:10.1002/14651858.cd006022.pub4

Cited by 39 publications

(32 citation statements)

References 67 publications

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“…Nevertheless, available data are often difficult to be interpreted due to the intricate underlying biochemistry and the not well-understood regulatory mechanisms. Principal investigations conducted appear often to be not rigorous and heterogeneous; moreover, methods and outcomes are not well standardized and acid production value is indirectly estimated with different modalities across studies so that data are difficult to be compared to a large extent (Escribano et al 2014;Phillips et al 2015). Hence, in our opinion, the role of WD in inducing clinically evident chronic disorders has yet to be more accurately evaluated.…”

Section: Resultsmentioning

confidence: 99%

“…(Ince et al 2004). An accurate Cochrane database meta-analysis of 2014 carried out examining clinical trials (total 379 subjects) confirmed that lower dietary protein and salt intake are associated with lower calcium excretion and consequently the recurrence of kidney stone episodes among patient suffering from idiopathic hypercalicuria (Escribano et al 2014).…”

Section: Urinary Stonesmentioning

confidence: 96%

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Diet-induced acidosis and alkali supplementation

Guardia

Roggi

Cena

2016

International Journal of Food Sciences and Nutrition

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Western diet, high in protein-rich foods and poor in vegetables, is likely to be responsible for the development of a moderate acid excess leading to metabolism deregulation and the onset or worsening of chronic disturbances. Available findings seem to suggest that diets with high protein/vegetables ratio are likely to induce the development of calcium lithiasis, especially in predisposed subjects. Moreover, some evidence supports the hypothesis of bone metabolism worsening and enhanced bone loss following acid-genic diet consumption although available literature seems to lack direct and conclusive evidence demonstrating pathological bone loss. According to other evidences, diet-induced acidosis is likely to induce or accelerate muscle wasting or sarcopenia, especially among elderlies. Furthermore, recent epidemiological findings highlight a specific role of dietary acid load in glucose metabolism deregulation and insulin resistance. The aim of this review is to investigate the role of acid-genic diets in the development of the mentioned metabolic disorders focusing on the possible clinical improvements exerted by alkali supplementation.

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Section: Resultsmentioning

confidence: 99%

Section: Urinary Stonesmentioning

confidence: 96%

Diet-induced acidosis and alkali supplementation

Guardia

Roggi

Cena

2016

International Journal of Food Sciences and Nutrition

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“…Plant fibers could combine with sugar and animal proteins, thus reducing their absorption rates (Escribano et al, 2014). In addition, most high-fiber vegetables have diuretic effects.…”

Section: Analysis Of Relevant Factors In 115 Cases Of <7-year-old Uygmentioning

confidence: 99%

A case-control study on the risk factors of urinary calculus in Uyghur children in the Kashi region

et al. 2015

Genet. Mol. Res.

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ABSTRACT. The incidence of urinary calculus (UC) is very high in Uyghur children in the Kashi region of Xinjiang, China, which seriously affects the growth and life quality of these children. This study was aimed at investigating the risk factors of UC in Uyghur children in Kashi region. One hundred fifteen Uyghur children (age <7 years) with UC who were treated in First People's Hospital in Kashi were enrolled in the case group. A 1:1 case-control study with a questionnaire was performed. The results showed that, among the 115 UC patients, there were more boys (71.3%) than girls (28.7%), and most cases had an onset age of 1-3 years (75.7%). A lower than primary school education in the mother, drinking unboiled water, water intake <500 mL/day, and eating too much sweets were risk factors [odds ratio (OR) = 2.385, 9.160, 3.263, and 8.945, respectively], whereas vegetable intake and exposure to summer sunshine of <2 h/day were protective factors against UC onset (OR = 0.154 and 0.344, respectively). Analysis of UC-related factors in 99 cases of <3-year-old children revealed that breastfeeding was also a protective factor (OR = 0.007), whereas frequent cow's milk intake within 5 months (OR = 2.414) and frequent "panada" intake (OR = 2.529) were risk factors. The occurrence of UC in Uyghur children in the Kashi region is mainly affected by maternal educational background, quality of drinking water, water intake volume, and dietary pattern. Furthermore, geography may also have a role.

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“…Several factors such as age, body size, and the intake of a number of nutrients influence urinary calcium excretion in humans [38,39,40]. It is known that a positive association exists between BMI and urinary excretion of sodium, calcium, uric acid, and citrate.…”

Section: Discussionmentioning

confidence: 99%

Reduced Bone Mass in 7-Year-Old Children with Asymptomatic Idiopathic Hypercalciuria

Escribano

Rubio-Torrents²,

Ferré

et al. 2014

Ann Nutr Metab

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Background: Idiopathic hypercalciuria (IHC), i.e. an elevated urinary calcium excretion without concomitant hypercalcemia, is a common disorder in children and can have a range of urinary clinical presentations and decreased bone mineral density (BMD). Aim: To assess the effect of IHC on bone mineral content in children without urological symptoms. Methods: Calcium excretion, BMD (by dual-energy X-ray absorptiometry), and anthropometry were assessed in 175 seven-year-old children who were classified as IHC or controls. Calcium intake and physical activity were measured as confounding factors. Results: The prevalence of IHC was 17.7%. Both groups (controls and IHC) showed similar baseline characteristics in terms of their anthropometry, gender distribution, and protein and calcium dietary intakes as well as physical activity scores. Urinary calciuria was independent of the calcium dietary intake and anthropometry. BMD correlated with anthropometry and physical activity but not with calcium dietary intake. IHC children had lower whole-body BMD z-scores compared to controls. The role of IHC in reducing the whole-body BMD z-score was still significant even when anthropometry, physical activity, and calcium intake were included as confounders in multivariate analyses. Conclusions: The prevalence of IHC in this population of 7-year-old children was about 17%. IHC diagnosis was associated with lower BMD z-scores and osteopenia in 22% of them.

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Dietary interventions for preventing complications in idiopathic hypercalciuria

Cited by 39 publications

References 67 publications

Diet-induced acidosis and alkali supplementation

Diet-induced acidosis and alkali supplementation

A case-control study on the risk factors of urinary calculus in Uyghur children in the Kashi region

Reduced Bone Mass in 7-Year-Old Children with Asymptomatic Idiopathic Hypercalciuria

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