Dietary mannan-oligosaccharides and their effect on chicken caecal microflora in relation to Salmonella Enteritidis colonization

Fernandez, F; Hinton, M.; Gils, B. Van

doi:10.1080/03079450120106000

Cited by 227 publications

(120 citation statements)

References 36 publications

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“…The roles of EG in AF detoxification were attributed first to have selective binding capacity for AF molecules (Devegowda, 1997;Diaz et al, 2002), second to modulate the immune response (Fernandez et al, 2002;Shashidhara and Devegowda, 2003) and third to provide nutrients to beneficial gut flora and to improve animal production (Newman, 1994;Fritts and Waldroup, 2003;Santin et al, 2003). It was hypothesized that EG might trap the AF molecule in its glucomannan matrix and prevent toxin absorption from the gastrointestinal tract (Raju and Devegowda, 2000).…”

Section: Discussionmentioning

confidence: 99%

Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin

Basmacıoğlu¹,

Oguz²,

Ergül³

et al. 2005

Czech J. Anim. Sci.

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The amelioration of aflatoxicosis in broiler chickens was examined by feeding two concentrations of yeast component (esterified glucomannan; EG). EG, incorporated into the diet at 0.5 and 1 g/kg, was evaluated for its ability to reduce the detrimental effects of 2 mg total aflatoxin (AF; 82.72% AFB1, 5.50% AFB2, 10.20% AFG1 and 1.58% AFG2) in diet on growing broiler chicks from 1 to 21 d of age. A total of 240 male broiler chicks (Ross-308) were divided into 6 treatment groups [control, AF, EG (0.5 g/kg), AF plus EG (0.5 g/kg), EG (1 g/kg), and AF plus EG (1 g/kg)]. Compared to the control, AF treatment significantly decreased body weight gain from week 2 onwards. AF treatment also caused significant decreases in serum total protein, albumin, total cholesterol, triglyceride, glucose, inorganic phosphorus, creatinine levels and alanine-aminotransferase (ALAT) activity but increased the aspartate-aminotransferase (ASAT) activity. Red blood cell, haematocrit, haemoglobin, thrombocyte, and lymphocyte counts and tibial crude ash levels were significantly reduced by AF treatment, while significant increases were seen in heterophil counts. The addition of EG (1 g/kg) to an AF-containing diet significantly improved the adverse effects of AF on haematological parameters, total protein, albumin values and ASAT activity. EG (1 g/kg) also partially improved body weight gains (59%) and the other biochemical parameters influenced by AF treatment. The addition of EG (both 0.5 and 1 g/kg) to the AF-free diet did not cause any considerable changes in the investigated values. These results clearly indicated that EG (1 g/kg) addition effectively diminished the adverse effects of AF on the investigated values. Also, the higher dietary concentration of EG (1 g/kg) was found more effective than the lower concentration (0.5 g/kg) against the adverse effects of AF on the variables investigated in this study.

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Section: Discussionmentioning

confidence: 99%

Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin

Basmacıoğlu¹,

Oguz²,

Ergül³

et al. 2005

Czech J. Anim. Sci.

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“…At the same time, the prebiotic mannanoligosaccharides not only prevent those pathogenic bacteria possessing type-1 fimbriae, such as E. coli, from attaching to gut wall but also displace them from the gut wall. A number of studies demonstrated that MOS are effective in reducing Salmonella infection of birds 10,20 Synbiotic supplemented broilers had significantly higher (p < 0.05) villus height in the duodenum, jejunum, ileum in comparison with the other treatments. Taller villi indicate more mature epithelia and enhanced absorptive function due to increased absorptive area of the villus.…”

Section: Discussionmentioning

confidence: 99%

The effects of prebiotic, probiotic and synbiotic supplementation on intestinal microbial ecology and histomorphology of broiler chickens

Abdel-Raheem¹,

Abd-Allah²,

Hassanein³

2012

IJAVMS

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A study was undertaken to evaluate the effect of prebiotic, probiotic and synbiotic supplementation on intestinal microflora and histomorphology of broilers. One-day-old Avian 48 chicks (n=100) were randomly assigned to 4 treatments (25 birds/treatment) for 6 week experiment. Each treatment consisted of 3 replicates (two replicate of 8 birds and one with 9 birds). Treatment groups were as follow: 1. Basal diet (control); 2. Basal diet plus MannanOligosaccharide (MOS) at levels of 2 g /kg of the starter diets and 0.5 g/kg of the grower diets); 3. Basal diet plus probiotic (3 g/kg diet, Saccharomyces cerevisiae); and 4. Basal diet plus the combination of pre and probiotics (synbiotic). On d 21 and 42, 3 birds per treatment were sacrificed to evaluate gut morphology and microbiology. Duodenum, jejunum, ileum, and cecum microflora composition and intestinal histomorphology were determined. The final body weight (BW), weight gain, feed conversion efficiency were significantly (p<0.05) higher in probiotic and synbiotic supplemented broilers compared with the control and prebiotic groups. Concentrations of bacteria belonging to Lactobacillus spp. in the duodenum and jejunum digesta at d 42 were significantly (P <0.05) higher in prebiotic supplemented broilers compared with the control and synbiotic treatments. However, synbiotic supplementation maintaining populations of unprofitable or potential pathogens (E. coli) at relatively low levels (numerically) in the small intestinal and cecal digesta. In addition, the total aerobes and coliform colony count were not significantly affected by any of the dietary treatment. Morphology data for the small intestine showed that synbiotic supplemented broilers had significantly higher (p < 0.05) villus height in the duodenum, jejunum, ileum in comparison with the other treatments. The crypt depths were numerically (p > 0.05) decreased in duodenum and ileum in synbiotic supplemented broilers. In addition, the age had significant effect on intestinal histomorphology. Moreover, the interaction between dietary treatment and age did not affect (p > 0.05) any of the intestinal histomorphological parameters.

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“…But some studies show that Salmonella infections stimulate inflammatory cytokine, interleukin-1 production [10,11] . Furthermore, MOS can competitively adsorbs pathogens from mannose and prevent their attack to gut epithelium [18] ; this can cause increase in energy intake which is helpful in cell-mediated immunity.…”

Section: Discussionmentioning

confidence: 99%

The Impacts of Prebiotic Supplementation on Humoral and Cell-Mediated Immune Responses of Broilers under Combined Stresses Caused by Feed Restriction and Salmonella enteritidis Challenge

Sadeghi¹,

Maddahian²,

Shawrang³

et al. 2013

Kafkas Univ Vet Fak Derg

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SummaryThis experiment was conducted to investigate the impacts of prebiotic on humoral and cell-mediated immune responses of broilers under combined stresses caused by feed restriction and Salmonella enteritidis challenge. 320 male broilers (Ross 308) at a 23 factorial arrangement in randomized complete block design were divided into 8 treatment groups with 4 replicates per each. The Impact of these factors and their interaction on cell-mediated immune response to cutaneous basophil hypersensivity (CBH) test, antibody titer response against Newcastle disease virus (NDV) and sheep red blood cell (SRBC), and the relative weight of lymphoid organs were measured. Prebiotic caused an increase and feed restriction caused a decrease in cell-mediated immune responses on days 15 and 30 respectively, and interaction among the factors was differ (P<0.05). Also, factors' interaction had a significant effect on antibody titer response against NDV (P<0.05) at day 27. Salmonella and feed restriction significantly reduced the relative weight of thymus at day 21 and bursa of Fabricius at day 42, respectively (p < 0.05). Differences among other measured parameters were not significant (P>0.05). Keywords: Prebiotic, Feed restriction, Salmonella, Humoral immune response, Cell-mediated immune response Prebiyotik İlavesinin Yem Kısıtlaması ve Salmonella enteritidis İnokulasyonu İle Kombine Stres Altındaki Broylerlerde Sıvısal ve Hücresel İmmun Yanıt Üzerine Etkileri ÖzetBu çalışma, prebiyotik ilavesinin yem kısıtlaması Salmonella enteritidis inokulasyonu ile kombine stres altındaki broylerlerde sıvısal ve hücresel immun yanıt üzerine etkileri araştırmak üzere gerçekleştirildi. Rastgele tam blok tasarım içinde 23 faktoriyel düzenlemede 320 erkek boyler (Ross 308) 4 tekrar olmak üzere 8 tedavi grubuna bölündü. Bu faktörlerin ve onların etkileşiminin hücresel immun cevap üzerin etkilerini belirlemek üzere kutanöz bazofil aşırı duyarlılık testi (CBH), Newcastle hastalığı (NDV) virüsü ve koyun eritrositlerine (SRBC) karşı gelişen antikor titreleri ve lenfoid organların göreceli ağırlıkları belirlendi. Hücresel immun yanıtı prebiyotik 15. günde arttırırken yem kısıtlamasını 30.günde azalttığı ve faktörler arası etkileşimin faklı (P<0.05) olduğu gözlemlendi. Ayrıca, faktörlerin etkileşiminin 27. gündeki NDV'ye karşı gelişen antikor titresinin gelişimi üzerine önemli etkisinin (P<0.05) olduğu belirlendi. Salmonella ve yem kısıtlamasının, timus ve bursa fabricius'un göreceli ağırlığını, sırasıyla 42. ve 21. günde azalttığı belirlendi (P<0.05). Diğer ölçülen parametreler arasında farklılıklar anlamlı bulunmadı (P>0.05).

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Dietary mannan-oligosaccharides and their effect on chicken caecal microflora in relation to Salmonella Enteritidis colonization

Cited by 227 publications

References 36 publications

Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin

Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin

The effects of prebiotic, probiotic and synbiotic supplementation on intestinal microbial ecology and histomorphology of broiler chickens

The Impacts of Prebiotic Supplementation on Humoral and Cell-Mediated Immune Responses of Broilers under Combined Stresses Caused by Feed Restriction and Salmonella enteritidis Challenge

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