Differences in colorectal cancer surveillance epidemiology and screening in the WHO European Region

Altobelli, Emma; Rapacchietta, Leonardo; Marziliano, Ciro; Campagna, Giuseppe; Profeta, Valerio F.; Fagnano, Roberto

doi:10.3892/ol.2018.9851

Cited by 14 publications

(20 citation statements)

References 24 publications

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“…Furthermore, CRC screening based on stool testing and flexible sigmoidoscopy has reduced CRC-related death rate by 16% and 22%−31%, respectively (34,35). The WHO ER examined the association factors in CRC surveillance epidemiology and screening, and found that available resources (as measured by gross national income) appear to be the major factor in the Colorectal Cancer Surveillance Epidemiology and Screening (36). According to results from studies focused on cost-effectiveness, CRC screening was cost-effective compared with no screening (37).…”

Section: Discussionmentioning

confidence: 99%

Burden of colorectal cancer in China, 1990−2017: Findings from the Global Burden of Disease Study 2017

Yin¹,

Bai²,

Zhang³

et al. 2019

Chinese Journal of Cancer Research

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Objective Our goal is to analyze the trend of colorectal cancer (CRC) regarding the death, incidence and prevalence rates over time, and to provide epidemiological knowledge basis for health policy revision by comparing data about fatal outcomes of CRC in 2017 to those data in 1990, which was extracted from the Global Burden of Disease (GBD). Methods The time trend and changes of CRC burden from 1990 to 2017 were measured by using the methods and results from the Institute for Health Metrics and Evaluation (IHME) GBD 2017, based on the rates of death, incidence and prevalence. Results The death rate of CRC is 13.24/100,000, accounting for 1.79% of total deaths in China in 2017. In 1990, CRC ranked 21st in all causes of death in China compared to its 11th ranking in 2017. The death, incidence and prevalence rate of CRC were standardized by the age scale of the global population in 2010, the change of standardized death rate of CRC was not significant, from 9.33/100,000 in 1990 to 10.10/100,000 in 2017. The standardized incidence rate of CRC significantly increased from 12.18/100,000 in 1990 to 22.42/100,000 in 2017. The standardized prevalence rate of CRC significantly increased from 44.55/100,000 in 1990 to 118.40/100,000 in 2017. The trend of the prevalence rate in both genders grow higher in 2017 compared to the 1990, resulting in 141.6%, 209.8% and 189.0% for the studied three age groups (15−49, 50−69 and 70+ years old), respectively. The death rate increased in the age groups of 50−69 and 70+ years in both genders (8.6% and 31.0% respectively), in contrast to a decrease of death rate in the age group of 15−49 years old (−10.8%). Conclusions China experienced a stunning increase in terms of incidence and prevalence rate of CRC from 1990 to 2017. To decrease the burden of CRC, prevention and management of known risk factors should be promoted through national polices.

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Section: Discussionmentioning

confidence: 99%

Burden of colorectal cancer in China, 1990−2017: Findings from the Global Burden of Disease Study 2017

Yin¹,

Bai²,

Zhang³

et al. 2019

Chinese Journal of Cancer Research

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“…The screening programs aim to identify patients with precancerous lesions or those with resectable CRC stages 0, I, and II, who have a generally better prognosis than symptomatic patients with the pre-existing disease [3]. Despite screening programs, many patients are diagnosed in the stages III and IV of CRC that lead to a worse overall prognosis [4]. According to data from National Cancer Institute from the United States of America (USA) [5], five years survival rates for stage IV account only for 12% at colon cancer (CC) and 13% at rectal cancer (RC), while detection at an early stage I can increase the chance to survive up to 92% at CC and 88% at RC [6].…”

Section: Introductionmentioning

confidence: 99%

Colorectal Adenomas—Genetics and Searching for New Molecular Screening Biomarkers

Siskova

Červená

Král

et al. 2020

IJMS

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Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new cases per year worldwide. CRC outcome is closely related to the respective stage of CRC and is more favorable at less advanced stages. Detection of early colorectal adenomas is the key to survival. In spite of implemented screening programs showing efficiency in the detection of early precancerous lesions and CRC in asymptomatic patients, a significant number of patients are still diagnosed in advanced stages. Research on CRC accomplished during the last decade has improved our understanding of the etiology and development of colorectal adenomas and revealed weaknesses in the general approach to their detection and elimination. Recent studies seek to find a reliable non-invasive biomarker detectable even in the blood. New candidate biomarkers could be selected on the basis of so-called liquid biopsy, such as long non-coding RNA, microRNA, circulating cell-free DNA, circulating tumor cells, and inflammatory factors released from the adenoma into circulation. In this work, we focused on both genetic and epigenetic changes associated with the development of colorectal adenomas into colorectal carcinoma and we also discuss new possible biomarkers that are detectable even in adenomas prior to cancer development.

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“…This data could be considered as an indicator of awareness with respect to food education policies and social habits which, however, appear to be very different between different nations, as in the case of Europe [61]. It is well known how the adoption of a healthy diet, with an adequate intake of carbohydrates, greatly reduces cardiovascular risk and obesity [62,63]. With respect to the consumption of soft drinks, it is noted that in Narain’s meta-analysis there is an increased risk for ischemic stroke in women [43].…”

Section: Discussionmentioning

confidence: 99%

Overview of Meta-Analyses: The Impact of Dietary Lifestyle on Stroke Risk

Altobelli

Angeletti

Rapacchietta

et al. 2019

IJERPH

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A stroke is one of the most prevalent cardiovascular diseases worldwide, both in high-income countries and in medium and low-medium income countries. The World Health Organization’s (WHO) report on non-communicable diseases (NCDs) indicates that the highest behavioral risk in NCDs is attributable to incorrect nutrition. The objective of our work is to present an overview of meta-analyses that have investigated the impact of different foods and/or drinks in relationship with the risk of stroke events (ischemic/hemorrhagic). The papers to be included in the overview were found in MEDLINE, EMBASE, Scopus, Clinicaltrials.gov, Web of Science, and Cochrane Library and were selected according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) flow chart. Quality assessment were made according to the AMSTAR 2 scale. This overview shows that all primary studies came from countries with high income levels. This evidence shows that many countries are not represented. Therefore, different lifestyles, ethnic groups, potentially harmful or virtuous eating habits are not reported. It is important to underline how the choose of foods may help reduce the risk of cardiovascular diseases and stroke in particular.

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Differences in colorectal cancer surveillance epidemiology and screening in the WHO European Region

Cited by 14 publications

References 24 publications

Burden of colorectal cancer in China, 1990−2017: Findings from the Global Burden of Disease Study 2017

Burden of colorectal cancer in China, 1990−2017: Findings from the Global Burden of Disease Study 2017

Colorectal Adenomas—Genetics and Searching for New Molecular Screening Biomarkers

Overview of Meta-Analyses: The Impact of Dietary Lifestyle on Stroke Risk

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