Different Types of Family History of Stroke and Stroke Risk: Results Based on 655,552 Individuals

Association between Family History of Stroke and Stroke Risk: A Community Survey

“…A positive association between participant’s stroke risk and family history of stroke observed in this secondary data analysis suggest that family history of stroke is an important factor to consider when assessing an individual’s risk of experiencing stroke. The genetic component of stroke has been carefully studied and is widely accepted (Floßmann et al, 2004; Meschia et al, 2014; Yu et al, 2019). A 2003 study evaluated the role of genetics in stroke occurrence, finding family history of stroke to be significant risk factor for stroke when the stroke occurred at an age ≤65 years (p=0.02; Jerrard-Dunne et al, 2003).…”

“…Family history of stroke is known to be a major risk factor for a person’s likelihood of experiencing stroke (Meschia et al, 2014; Yu et al, 2019). While family history of stroke is not a modifiable stroke risk factor, factors such as hypertension, smoking, physical inactivity, alcohol abuse, and obesity are modifiable through treatment or lifestyle changes (Meschia et al, 2014; Sakakibara et al, 2017; Sauerbeck, 2006).…”

“…One predominant risk factor is family history of stroke. Family history of stroke largely contributes to stroke development, and can be useful for predicting stroke risk (Yu et al, 2019). A positive family history of stroke is associated with a near 30% increase in a person's risk of experiencing stroke (Floßmann, Schulz, & Rothwell, 2004).…”

“…A positive family history of stroke is associated with a near 30% increase in a person's risk of experiencing stroke (Floßmann, Schulz, & Rothwell, 2004). The specific type of family history of stroke relation (sibling/ parent, maternal/paternal) does not have a significant impact on the degree of risk a person has for experiencing a stroke (Yu et al, 2019). As a result, collecting a thorough family history is an important primary prevention measure for stroke (Meschia et al, 2014).…”

Chinese Guideline on the Primary Prevention of Cardiovascular Diseases

“…For individuals with a moderate 10-year risk, intervention strategies should be determined by considering risk-enhancing factors [52][53][54][55][56][57][58][59][60][61][62][63][64][65][66] IIa B ASCVD: Atherosclerotic cardiovascular disease; CKD: Chronic kidney disease; COR: Class of recommendation; LDL-C: Low-density lipoprotein cholesterol; LOE: Level of evidence; TC: Total cholesterol.…”