Dilobenol A–G, Diprenylated Dihydroflavonols from the Leaves of <i>Dilobeia thouarsii</i>

Razafintsalama, Voahiraniaina; Girardot, Marion; Randrianarivo, Ranjana; Rakoto, Danielle; Sarter, Samira; Petit, Thomas; Ralambonirina, Sylvia; Deville, Alexandre; Grellier, Philippe; Jeannoda, Victor; Mambu, Lengo

doi:10.1002/ejoc.201201421

Cited by 7 publications

(4 citation statements)

References 24 publications

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“…Different types of assays were used in the cytotoxic analysis of the Proteaceae species, including trypan blue dye [173], the MTT assay [98,151,155,[174][175][176][177][178][179], XTT assay [159], MTS assay [143,[180][181][182], WST-1 assay [38], brine shrimp lethality assay [138,183,184], resazurin reduction assay [185], and fluorescein diacetate assay [152]. Most of the studies chose HepG2, the isolation of hepatocellular carcinoma, to be considered as the cell line.…”

Section: Cytotoxicitymentioning

confidence: 99%

A Review of Phytochemicals and Bioactive Properties in the Proteaceae Family: A Promising Source of Functional Food

Zhang,

Netzel,

Pengelly

et al. 2023

Antioxidants

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In recent decades, natural plant-based foods have been increasingly used to improve human health due to unhealthy modern dietary patterns, such as the consumption of foods high in sugar and fat. Many indigenous species have been used by Aboriginal peoples for their food and therapeutic properties. Thus, it is important to understand the health-enhancing bioactive profile of Australian indigenous species. The Proteaceae family, such as the genera of Protea, Macadamia, and Grevillea, have been commercially used in the horticulture and food industries. Researchers have reported some findings about Persoonia species, one of the genera in the Proteaceae family. The aim of this review was to provide an overview of the family Proteaceae and the genus Persoonia, including distribution, traditional and commercial uses, phytochemicals, bioactive properties, potential opportunities, and challenges. In this review, bioactive compounds and their properties related to the health benefits of the Proteaceae family, particularly the Persoonia genus, were reviewed for potential applications in the food industry.

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Section: Cytotoxicitymentioning

confidence: 99%

A Review of Phytochemicals and Bioactive Properties in the Proteaceae Family: A Promising Source of Functional Food

Zhang,

Netzel,

Pengelly

et al. 2023

Antioxidants

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“…The new flavonoid glucosides revealed no cytotoxicity against the usual cancer cell lines, such as A549, CaSki, DLD-2, and MCF-7, although they inhibited both matrix metalloproteinases activity and tumor necrosis factor-α production in THP-1 cells treated with lipopolysaccharide, suggesting that these new flavonoids may be useful for the treatment of inflammatory diseases. 34) Investigation of the EtOAc extract of the leaves of…”

Section: Flavonoids Bioassay-guided Fractionation Of An Ethanol Extramentioning

confidence: 99%

Novel Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms (2009–2017)

Dai

Liu

Rakotondraibe

2018

CHEMICAL & PHARMACEUTICAL BULLETIN

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Madagascar's rain forests and tropical dry forests are home to numerous endemic plant species and the island is considered a biodiversity hotspot. About 80% of the Madagascan (Malagasy) population relies on traditional medicines that have been proven to contain a variety of biologically active compounds. In the search for bioactive compounds from Madagascan biodiversity, we accessed and collected most of the literature dealing with the isolation, structure elucidation, and biological activities of organic small molecules originating from Madagascan plants and marine organisms. Since we published the first review of this work in 2009 (Curr. Med. Chem., 17, 2010, Hou and Harinantenaina), the present paper covers the isolation, structures, and bioactivity of 182 new secondary metabolites isolated from Malagasy higher plants and marine organisms in the last seven years (2009-2017).

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“…The current study is a part of a wide program on toxic plants aiming to find compounds of interest such as pesticides molecules [10][11][12][13]. It is a continuation of the previous works on the toxic activity of the endemic species of Albizia of Madagascar on various organisms [13][14][15][16][17]. It was conducted in order to determine the effects of the seed methanolic extracts from six other species (A. bernieri, A. androyensis, A. divaricata, A. greveana, A. masikororum and A. viridis) on the germination of seeds and the early growth of seedlings.…”

Section: Introductionmentioning

confidence: 99%

Phytotoxic Property of Seed Methanolic Extracts from Albizia (Fabaceae) Endemic Species of Madagascar

Randrianarivo¹

2014

JPS

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Investigations on the phytotoxicity of Albizia species were conducted under laboratory conditions in order to assess their possible use in the control of weeds and invasive plants. The effects of seed methanolic extracts obtained from A. androyensis, A. bernieri, A. divaricata, A. greveana, A. masikororum and A. viridis, all endemic of Madagascar were evaluated against seed germination and early seedling development of vegetables (Phaseolus vulgaris, Pisum sativum, Petroselinum crispum, Brassica sp., Cucumis sp., Allium cepa, Zea maÿs and Oryza sativa). The effects of these extracts on seed germination of weeds (Eragrostis pilosa, and Panicum subalbidum) and invasive plants (Acacia dealbata, Cassia rotundifolia and Pinus kesyia) were also studied. Globally, all the extracts (1 mg/mL) inhibited the seed germination of all the test plants. However, the inhibitory effect varied according to both the Albizia extract and the target plants. Inhibition rates could reach 100%. The extracts (0.45 to 7 mg/mL) also significantly (p<0.05) reduced the length of both epicotyl and hypocotyl and the effects were generally in a dose dependent manner. At the same concentration (7.2 mg/mL) with some extracts, the inhibitory effect was as high as glyphosate, a weed-killer widely used in agriculture. At low concentrations (0.45-0.9 mg/mL) a high stimulatory effect of up to 200% was observed with some extracts. Overall, the results obtained supported the probable involvement of seed secondary metabolites in the allelopathic interactions of Albizia species with other plants and could be exploitable in the control of undesirable plants.

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Dilobenol A–G, Diprenylated Dihydroflavonols from the Leaves of Dilobeia thouarsii

Cited by 7 publications

References 24 publications

A Review of Phytochemicals and Bioactive Properties in the Proteaceae Family: A Promising Source of Functional Food

A Review of Phytochemicals and Bioactive Properties in the Proteaceae Family: A Promising Source of Functional Food

Novel Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms (2009–2017)

Phytotoxic Property of Seed Methanolic Extracts from Albizia (Fabaceae) Endemic Species of Madagascar

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