Direct electrochemiluminescent immunosensing for an early indication of coronary heart disease using dual biomarkers

Lian, Xiaoting; Feng, Zibo; Tan, Rong; Mi, Xiaona; Tu, Yifeng

doi:10.1016/j.aca.2020.03.022

Cited by 10 publications

(1 citation statement)

References 45 publications

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“…CEA levels were then measured using ECL, and the fabricated immunosensor showed an LOD of 0.029 pg/mL with a linear range of 0.0001-100 ng/mL. Lian et al developed a label-free ECL immunosensor using Au-Co alloy NPs (Au-Co NPs) for the detection of LDL and oxidized LDL (ox-LDL) [104]. Au-Co NPs were immobilized onto an APTMS-silanized electrode, and each antibody against LDL and ox-LDL was immobilized.…”

Section: Physical Adsorption Of Antibodiesmentioning

confidence: 99%

Recent Progress in Electrochemical Immunosensors

Kim

Park

2021

Biosensors

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Biosensors used for medical diagnosis work by analyzing physiological fluids. Antibodies have been frequently used as molecular recognition molecules for the specific binding of target analytes from complex biological solutions. Electrochemistry has been introduced for the measurement of quantitative signals from transducer-bound analytes for many reasons, including good sensitivity. Recently, numerous electrochemical immunosensors have been developed and various strategies have been proposed to detect biomarkers. In this paper, the recent progress in electrochemical immunosensors is reviewed. In particular, we focused on the immobilization methods using antibodies for voltammetric, amperometric, impedimetric, and electrochemiluminescent immunosensors.

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Section: Physical Adsorption Of Antibodiesmentioning

confidence: 99%