Disability-Adjusted Life Year (DALY) assessment and economic damage from premature death of cervical uterine and ovarian cancers in the Tomsk Region

Жуйкова, Л. Д.; Ананина, О А; Sirotina, Alina S.; Пикалова, Л. В.; Fokin, V. A.; Kononova, G. A.

doi:10.26442/18151434.2022.4.201709

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…Радикальное противоопухолевое лечение РТМ сопряжено с различными местными и/или общими осложнениями [4][5][6], приводящими к стойким нарушениям функций организма человека и влияющими на формирование первичной инвалидности . Инвалидизация населения, в частности медицинский, социальный и экономический аспекты, в свою очередь, наносит государству значительный экономический ущерб [7,8] .…”

Section: обоснованиеunclassified

Analysis of the structure and dynamic of disability of uterine cancer patients in the Volgograd region

Zhavoronkova,

Grushina,

Suvorov

2024

Medical and Social Expert Evaluation and Rehabilitation

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BACKGROUND: Among oncogynecological pathology, uterine cancer occupies the first rank place. A significant number of patients are women of working age, which makes the analysis of their disability relevant. AIM: Analysis of primary and repeated disability of uterine cancer patients in the Volgograd region. MATERIALS AND METHODS: The object of the study were 1978 patients with uterine cancer, who were recognized as disabled for the first time and again. The study period included 2018–2022 with an annual analysis of the number of disabled people in three age groups: young (18–44 years), middle (45–54 years) and older (55 years and older) age. Research methods: analysis of statistical forms, statistical analysis. RESULTS: Of the 1978 disabled: in 2018 there were 374 (18.9%), in 2019 — 346 (17.5%), in 2020 — 371 (18.8%), in 2021 — 429 (21.7%), in 2022 — 465 (23.5%) women. The total number of disabled has increased by 19.5% in 5 years (from 374 to 465). The age structure of the disabled: young patients accounted for 109 (5.5%), middle — 325 (16.5%) and older — 1544 (78%). Of all the patients, disability I gr. was established in 117 (5.9%), II gr. in 295 (14.9%) and III gr. in 1566 (79.2%). The structure of disability severity in three age groups remained stable for 5 years (p=0.35). In all age groups, there was increase in repeated disability, especially significant in older age group. CONCLUSION: In the course of the analysis of the structure and dynamics of disability of patients with malignant neoplasms of the uterus in the Volgograd region for 5 years, multidirectional trends were established. Based on the data obtained, it is advisable to plan further work to prevent disability and restore the ability of patients to work.

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Section: обоснованиеunclassified

Analysis of the structure and dynamic of disability of uterine cancer patients in the Volgograd region

Zhavoronkova,

Grushina,

Suvorov

2024

Medical and Social Expert Evaluation and Rehabilitation

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Analysis of years of life lost due to premature cancer mortality in the Russian Federation

Khailova,

Kaprin,

Omelyanovsky

et al. 2023

Sib. onkol. ž.

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Background. Burden of disease estimation allows analyses to be carried out integrally, including cause and effect assessment. the rate of life years lost due to premature mortality is part of the burden of disease analysis. given that the burden of cancer is steadily increasing, analysis of the number of years lost makes it possible to identify new strategic directions, as well as to adjust decisions already made, in the health care of cancer patients.Purpose: to estimate the loss of life expectancy as a result of premature mortality from cancer in the population of the Russian Federation.Material and Methods. the analysis was carried out using international statistical databases for disease burden estimation, databases of the Federal state statistics service (Rosstat). to determine the target groups of priority reduction of mortality from neoplasms in the Russian Federation, an estimation of the lost years of life expectancy as a result of premature mortality in the form of the e† (e-dagger) indicator was carried out. the analyzed period of the study was 2010–2019.Results. the Russian Federation is characterized by the smallest share of losses from cancer in the structure of losses from all causes of death compared to the analyzed countries (Japan, France, germany, latvia, lithuania, estonia). However, the share of losses has been intensively increasing for 10 years (in 2010 – 14.79 %, in 2019 – 17.54 %). in comparison with the analyzed countries, Russia is more characterised by losses from cancer at a younger age, with the highest value of life years lost in the age group 60–64 years. the age-standardized number of years lost in men in Russia is 67.1 % higher than in women. in the age group from 25 to 49 years of age, the loss of life expectancy due to cancer in women is higher and accounts for 0.4 years (or 19 %) of all losses, which is not typical of other age groups in which losses in men prevail. A significant regional differentiation of mortality in the constituent entities of the Russian Federation has been revealed, which is also reflected in the number of years lost.Conclusion. the potential of preventive strategies in the Russian Federation has not been fully realized – the loss of life years in young and middle age requires the correction of measures to improve preventive services and oncological care. the revealed regional differentiation allows us to identify regions with high losses for priority solutions.

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Gender-age peculiarities of disability-adjusted life years (DALYs) in tuberculosis in a high-density region: a retrospective cohort study

Zagdyn,

Kobesov,

Pagieva

et al. 2024

Kuban. nauсh. med. vestnik

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Background. Infections associated with socially significant diseases considerably contribute to a decrease in the quality of public health. Tuberculosis, though declining in Russia, is still recognized as a pressing public health problem. Meanwhile, an assessment of the burden of tuberculosis on society, using such comprehensive methods as measuring disability-adjusted life years, is yet to be investigated in Russia. Objective. To estimate the tuberculosis burden by calculating the index of disability adjusted life years in a high-density region.Methods. The retrospective cohort study involved data on newly-diagnosed and died of tuberculosis cases that corresponded to the annual reporting form of federal statistical surveillance No. 8 “Information on active tuberculosis cases” for the Republic of North Ossetia-Alania; information on patients who died of tuberculosis or tuberculosis combined with infection caused by human immunodeficiency virus, was obtained from the Department of Civil Status Records of the Republic of North Ossetia-Alania and verified with data from the Federal State Statistics Service; data on tuberculosis-associated disability was received from Main Bureau of Medical and Social Expertise in the Republic of North Ossetia-Alania of the Ministry of Labor and Social Protection of the Russian Federation for 2018 and 2022. Following the analytic dataset, 691 people with newly-diagnosed tuberculosis, who received TB-associated disability and died from TB in 2018 (318 people) and 2022 (373 people) were identified. The study involved calculation of gender and age standardized TB morbidity and mortality rates as well as DALY index with its components: Years of Life Lost due to tuberculosis and Years Lost due to Disability. The study involved comparing data between 2018 and 2022 and gender/age-specific indicators within the same year. Mathematical data processing was performed using Microsoft Excel 2017 (Microsoft Corporation, USA) and SPSS 26.0 (SPSS Inc., USA). Differences between the compared indicators were evaluated by Chi-square criterion with variations, the initial data were grouped in a contingency table, the significance of differences was expressed by p-value.Results. The burden of tuberculosis in the Republic of North Ossetia-Alania refers predominantly to the male population: with a gender difference in the decrease in the disability-adjusted life years in 2018 and 2022 by 4.4 and 9.0 times (p < 0.05), respectively; 2.8 times among males, 5.5 times among females (p < 0.05). The burden of tuberculosis is mainly associated with premature mortality due to tuberculosis among males aged 35–54 years and among females aged 35–44 years with a pronounced decrease in Years of Life Lost. Years of Life Lost among males aged 20–34 in 2022 appears two times higher than the cohort average. The increase in Years of Life Lost among males aged 60–64 accounted for 1.7 times, in Years Lost Due to Disability — 11.2 times (p < 0.05). Years Lost Due to Disability among females aged 20–44 years appeared to be the highest, exceeding the cohort average by more than two times in 2018.Conclusion. The burden of tuberculosis is predominantly due to tuberculosis-related premature mortality among the male population. According to the disturbing conclusion, Years of Life Lost among young males aged 20–34 years and tuberculosis-related premature mortality shift towards the male population of pre-retirement age (60–64 years) with an increase in Years Lost Due to Disability among them. Notably, the study reveals high rates of Years Lost Due to Disability among females aged 20–44. The results obtained should be taken into account when developing regional tuberculosis programs with their targeted use in “vulnerable” age and gender groups of the population.

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Disability-Adjusted Life Year (DALY) assessment and economic damage from premature death of cervical uterine and ovarian cancers in the Tomsk Region

Cited by 3 publications

References 12 publications

Analysis of the structure and dynamic of disability of uterine cancer patients in the Volgograd region

Analysis of the structure and dynamic of disability of uterine cancer patients in the Volgograd region

Analysis of years of life lost due to premature cancer mortality in the Russian Federation

Gender-age peculiarities of disability-adjusted life years (DALYs) in tuberculosis in a high-density region: a retrospective cohort study

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