Background. Disability-adjusted life year (DALY) is one of the well-known methods of comprehensive health assessment in the world. The method was developed by the World Bank and the World Health Organization. The DALY units and gross domestic product per capita are used for the assessment of the indirect economic damage from premature death of cancer. Aim. To estimate the number of years of life lost (DALY method) and economic losses due to death from cervical, uterine and ovarian cancers in the population of the Tomsk region. Materials and methods. The data of the Tomsk Region Federal State Statistics Service on the mortality of the population of the reporting form C51 Distribution of the dead by sex, age groups and causes of death, data on the sex and age distribution of the population, life expectancy, gross regional product per capita for 2018 of the Tomsk region were used. Results. In 2018, due to the death from gynecological cancer of the population of the Tomsk Region, 1616 DALY units were lost in absolute numbers. Of these, cervical cancer accounts for 44.3% (717 DALY units), uterine corpus cancer accounts for 24.8% (401 DALY units), ovarian cancer accounts for 30.8% (498 DALY units). At working age (1654 years), the absolute losses amounted to 694 DALYs. The economic damage to the Tomsk Region due to the mortality of the population from cancer of the cervix, uterine body and ovaries in 2018 amounted to 918.2 million rubles. Economic losses as a result of mortality from cancer of the cervix amounted to 407.4 million rubles, from cancer of the ovaries 283.0 million rubles, from cancer of the body of the uterus 227.8 million rubles. The economic damage from gynecological cancers in working age amounted to 394.3 million (42.9% of the total economic damage). Conclusion. Determining the socio-economic losses associated with mortality from malignant neoplasms of the female genital organs is necessary for the effective use of health care resources, which can be used to justify the need of the population for oncological care.

Significance. During the spread of the new coronavirus infection (COVID-19), digital technologies have proved to be promising organizational solutions, opening up new opportunities for managing the epidemiological process and enhancing adaptability of healthcare systems to the increased workload. Studying the experience of using computer technologies in a difficult epidemiological situation is necessary to identify main directions, results and problems related to the implementation of digital transformation in health during a pandemic. The purpose of the study is to summarize the experience of using modern digital technologies to optimize performance of healthcare systems in the context of the COVID-19 pandemic. Material and Methods. The following databases were searched for publications: PubMed, Scopus, ScienceDirect, Google Scholar, Web of Science, eLibrary. Various combinations of the words "COVID-19", "digital health", "telemedicine", "artificial intelligence", "machine learning", "internet of things (IoT)", "chatbot" were used as keywords. A total of 362 publications were analyzed, from which 36 studies corresponding to the chosen topic were selected. Results. Analysis of the experience of using modern digital technologies to optimize performance of healthcare systems in the context of the COVID-19 pandemic has shown that digital solutions can reduce burden on healthcare institutions and contribute to organizing an accessible and high-quality medical care by automated processes of diagnosis and triage. Care delivery through remote technologies has both reduced the risk of infection for patients and doctors by eliminating personal contacts and opened up new avenues of work of medical personnel. However, many issues related to the use of digital technologies in health remain unresolved, for example, patient data confidentiality, access to digital technologies among population, legal regulation, economic feasibility, etc. Conclusion. In a number of countries digital technologies have much supported the healthcare system during the COVID-19 pandemic. Further improvement of digital health tools, scale-up and analysis of medical, social and cost-effectiveness of their use can play an important role in optimizing the processes of diagnosis, treatment and prevention of not only the COVID-19, but also other diseases. To ensure a widespread and viability of digital technologies in healthcare, it is necessary to address the legal and financial issues associated with their use.