Radiation emitted by nonthermal particles accelerated during relativistic magnetic reconnection is critical for understanding the nonthermal emission in a variety of astrophysical systems, including blazar jets, black hole coronae, pulsars, and magnetars. By means of fully kinetic particle-in-cell simulations, we demonstrate that reconnection-driven particle acceleration imprints an energy-dependent pitch-angle anisotropy and gives rise to broken power laws in both the particle energy spectrum and the pitch-angle anisotropy. The particle distributions depend on the relative strength of the non-reconnecting (guide field) versus the reconnecting component of the magnetic field (B
g
/B
0) and the lepton magnetization (σ
0). Below the break Lorentz factor γ
0 (injection), the particle energy spectrum is ultra-hard (p
< < 1), while above γ
0, the spectral index p
> is highly sensitive to B
g
/B
0. Particles’ velocities align with the magnetic field, reaching minimum pitch angle α at a Lorentz factor
γ
min
α
controlled by B
g
/B
0 and σ
0. The energy-dependent pitch-angle anisotropy, evaluated through the mean of
sin
2
α
of particles at a given energy, exhibits power-law ranges with negative (m
<) and positive (m
>) slopes below and above
γ
min
α
, becoming steeper as B
g
/B
0 increases. The generation of anisotropic pitch-angle distributions has important astrophysical implications. We address their effects on regulating synchrotron luminosity, spectral energy distribution, polarization, particle cooling, the synchrotron burn-off limit, emission beaming, and temperature anisotropy.