Disinfectant activities of extracts and metabolites from Baccharis dracunculifolia DC

Bernardes, Cristiane Teixeira Vilhena; Ribeiro, Victor Pena; Carvalho, Tiago; Furtado, Ricardo Andrade; Furtado, Niege Araçari Jacometti Cardoso; Bastos, Jairo Kenupp

doi:10.1111/lam.13725

Cited by 6 publications

(4 citation statements)

References 25 publications

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“…In addition, when the substances isolated from the extracts were evaluated, baccharin (Figure 6) showed activity against S. aureus and T. mentagrophytes, and isosakuranetin (Supplementary Figure S3) against Salmonella choleraesuis and T. mentagriphytes. According to the results found in this work, B. dracunculifolia is a potential alternative as a sanitizer against pathogenic fungi and bacteria (Bernardes et al, 2022). Assumpção et al (2022) evaluated the antimicrobial activity of the hydroalcoholic extract of aerial parts of B. dracunculifolia against strains of S. aureus isolated from mastitis.…”

Section: Extractmentioning

confidence: 78%

“…Even the ethanol extract having a higher content of phenols and flavonoids had a lower antimicrobial capacity (Veiga et al, 2017). Bernardes et al (2022) tested the antimicrobial activity of hydroalcoholic extracts from aerial parts and roots and trichome washing of B. dracunculifolia against bacterial and fungal strains. The best results were against S. aureus (MIC 200 μg/ml for the extract of aerial parts and trichome wash) and Trichophyton mentagrophytes (MIC 200 μg/ml for the extract of aerial parts).…”

Section: Extractmentioning

confidence: 99%

“…Research carried out with B. dracunculifolia indicates biological activities such as anti-inflammatory ( Santos et al, 2010 ; Brandenburg et al, 2020 ; França et al, 2022 ), antiulcerogenic ( Klopell et al, 2007 ; Lemos et al, 2007 ; Massignani et al, 2009 ; Costa et al, 2019 ; Boeing et al, 2021 ), immunomodulatory ( Burgos et al, 2022 ), neuroprotective ( França et al, 2022 ), antioxidant ( Veiga et al, 2017 ; Casagrande et al, 2018 ; Tomazzoli et al, 2021 ; Luchesi et al, 2022 ; Monteiro et al, 2022 ); antimicrobial ( Veiga et al, 2017 ; Casagrande et al, 2018 ; Salazar et al, 2018 ; Cazella et al, 2019 ; Pedrotti et al, 2019 ; Bonin et al, 2020 ; Timbé et al, 2021 ; Barbosa et al, 2022 ; Bernardes et al, 2022 ; Monteiro et al, 2022 ), anti-phytopathogenic ( Luchesi et al, 2022 ), insecticide and acaricide ( Chaaban et al, 2018 ; Cazella et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)

et al. 2022

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Baccharis dracunculifolia DC (Lamiaceae) (Asteraceae) is found in South America, mainly in Argentina, Brazil, Bolivia, Paraguay and Uruguay. Folk medicine is used as a sedative, hypotensive, bronchodilator, cardiovascular disorders, anti-flu, and also in skin wounds. Considered the main source of green propolis, which increases the pharmacological interest in this species. It is also known as a “benefactor” plant facilitating the development of other plant species around it, being indicated for the recovery of degraded areas. This species has been studied for decades in order to isolate and identify the active principles present in the aerial parts (leaves and flowers) and roots. The present study consists of a review of the scientific literature addressing the ethnobotanical, ethnomedicinal, phytochemical, pharmacological and potential cytotoxic effects of the B. dracunculifolia species. In this survey, we sought to investigate issues related to the botanical and geographic description of the species, the ethnobotanical uses, as well as the phytochemical studies of the essential oil, extracts and green propolis obtained from the aerial parts and roots of B. dracunculifolia. Using high precision analytical tools, numerous compounds have already been isolated and identified from leaves and flowers such as the flavonoids: naringenin, acacetin, dihydrokaempferol, isosakuranetin and kaempferide; phenolic acids: p-coumaric, dihydrocoumaric, ferulic (E)-cinnamic, hydroxycinnamic, gallic, caffeic, and several caffeoylquinic acids derivatives; phenolic acids prenylated: artepillin C, baccharin, drupanin; the glycosides dracuculifosides and the pentacyclic triterpenoids: Baccharis oxide and friedelanol. The predominant class in the essential oil of leaves and flowers are terpenoids comprising oxygenated monoterpenes and sesquiterpenes, highlighting the compounds nerolidol, spathulenol, germacrene D and bicyclogermacrene. These compounds give the species high antimicrobial, antioxidant, antitumor, analgesic, immunomodulatory and antiparasitic potential, making this species a promising herbal medicine. In vitro toxicity assays with B. dracunculifolia extract showed low or no cytotoxicity. However, in vivo analyses with high doses of the aqueous extract resulted in genotoxic effects, which leads us to conclude that the toxicity of this plant is dose-dependent.

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Section: Extractmentioning

confidence: 78%

Section: Extractmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)

et al. 2022

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“…It is the primary plant source of Southeastern Brazilian propolis, called green propolis, because of its color. Green propolis contains high levels of prenylated p -coumaric acids, mainly artepillin C and baccharin, and the volatile compounds nerolidol and spathulenol, all found in B. dracunculifolia (Beserra et al 2021 ; Bernardes et al 2022 ).…”

Section: Discussionmentioning

confidence: 99%

Brazilian Brown Propolis: an Overview About Its Chemical Composition, Botanical Sources, Quality Control, and Pharmacological Properties

Ribeiro

Mejía²,

Rodrigues³

et al. 2023

Rev. Bras. Farmacogn.

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Brazil is one of the largest propolis producers in the world. Propolis is produced by bees from plant exudates and tissues, leading to many variations in the types of propolis. Generally, Brazilian propolis types are green, brown, and red. Despite not being the main research focus as the green and red propolis, brown propolis is the second most produced propolis type in Brazil and has tremendous economic and medicinal importance. Propolis has drawn attention with the rise in the search for healthier lifestyles, functional foods, biocosmetics, and natural products as therapeutic sources. This review covers the main chemical constituents identified in different types of Brazilian brown propolis, and their botanical sources, chemistry, and biological activities. The economic aspect of brown propolis is also presented. There are many gaps to be filled for brown propolis regarding the development of analytical methods, and quality control to allow its standardization, limiting its applicability in the food and pharmaceutical industries. Future perspectives regarding brown propolis research were discussed, especially biological activities, to support the medicinal uses of different types of brown propolis. Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1007/s43450-023-00374-x.

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Antimicrobial activity in Asterceae: The selected genera characterization and against multidrug resistance bacteria

Gou¹,

Lu²,

Xie³

et al. 2023

Heliyon

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Disinfectant activities of extracts and metabolites from Baccharis dracunculifolia DC

Cited by 6 publications

References 25 publications

Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)

Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)

Brazilian Brown Propolis: an Overview About Its Chemical Composition, Botanical Sources, Quality Control, and Pharmacological Properties

Antimicrobial activity in Asterceae: The selected genera characterization and against multidrug resistance bacteria

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