Disinfection and environment

Mandyhra, M.; Lysytsya, A. V.; Volovyk, G.; Mandyhra, Yu.M.; Boyko, O. A.

doi:10.31073/vet_biotech32(2)-44

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Відомо, що якість дезінфекції безпосередньо залежить від якості дезінфікуючих засобів, використаних для її проведення. Згідно з сучасними вимогами ефективними вважають лише ті дезінфектанти, які володіють високою бактерицидною активністю і широким спектром антимікробної дії, зумовлюють швидку загибель патогенних агентів, не викликають подразнення шкіри і слизової органів дихання та очей, не втрачають своєї активності впродовж тривалого часу в процесі зберігання, легко утилізуються і не шкідливі для довкілля (Morozova et al, 2015;Mandyhra et al, 2018;Ravliv & Solovei, 2020).…”

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Retrospective analysis of production of main active ingredients and assortment of disinfectants in Ukraine

Мирончук

Peleno

2023

SMLNUVMB

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There are practically no disinfectants on the market of veterinary drugs that fully meet the requirements. This is due to the significant diversity and peculiarity of the structure of microorganisms and their ability to form resistance during long-term use of the same disinfectants. This is one of the reasons for the active search for effective active substances, the development of new drugs, and their registration, contributing to quite intensive changes in the range of disinfectants on the market. The work aimed to analyze the production, determine the share of domestic and imported disinfectants, determine the main active substances, and the range of disinfectants registered in Ukraine. The research material was a list of disinfectants registered in Ukraine used in animal husbandry, veterinary and humane medicine, and the food industry. It was established that from 2018 to 2022, 66 domestic and imported disinfectants were registered in Ukraine. Imported disinfectants are produced mainly in Great Britain, France, Belgium, Spain, Germany, Israel, Slovenia, Denmark, and the Netherlands. From among domestic companies, PP “Kronos Agro”, LLC “BioTestLab”, LLC “SANFORT-P”, LLC “Brovapharma”, LLC “Ukrvetprompostach”, LLC “Ukrainian-Polish joint enterprise “ZVK”, LLC “VetAgro” are engaged in the production of disinfectants, LLC “Inter-Syntez”, LLC “Ukrainian Chemical Technologies LTD”, LLC “GREENPAKS”, LLC NVK “Globus”, LLC “Vetsyntez”, PF “Termit”, LLC “ABM-Trade”, LLC “Dezsystema”, LLC “Tandem-2002”, NVPP “DEZO” and LLC “UKRTEK KO”. It was determined that manufacturers often use chlorine and oxygen as active ingredients, and the number of products with one active ingredient is relatively insignificant. Most often, the active substance of modern disinfectants is quaternary ammonium salts in combination with aldehydes. Their number is 33.4 % of all registered means. This means combining QAS and acids and QAS and oxygen compounds takes 3.2 times less time. Means containing other combinations of active substances are from 1.5 to 4.6 %. It was established that the leader in the production of imported “cleansing probiotics” (PIP – Probiotics In Progress) is the British company “Ingenious Probiotics”, which produces 66.7 % of registered products. Three companies produce this kind of disinfectant in our country; their assortment includes 23 names, and the largest share belongs to the company “Sirion”.

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Section: вступunclassified

Retrospective analysis of production of main active ingredients and assortment of disinfectants in Ukraine

Мирончук

Peleno

2023

SMLNUVMB

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Influence of “Brovadez-plus” disinfectant in different concentrations on Eimeria oocysts in calves

Bogach

Skalchuk

Kushak

2019

Veterinary Medicine: Inter-Departmental Subject Scientific Collection

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The purpose of work was to determine the effect of different concentrations of “Brovadez-plus” disinfectant solution on the sporulation process of mixed culture of eimerias oocysts of calves. Disinvasive activity of the drug “Brovadez-plus” was determined at concentrations of 1.5, 2, 3 and 3.5% for exposures of 3, 5 and 8 hours by irrigation of oocysts. The drug “Brovadez-plus’ at 2% concentration for 3 hours exposure showed an eimeriostatic effect at the level of 29.9 ± 1.4%. At 5 hours exposure, sporogonia did not undergo 51.1 ± 0.5% oocysts, and at 8 hours exposure 64.4 ± 2.2% eimerias oocysts of calves. When using 3% concentration of “Brovadez-plus” solution for 3 hours, sporulation process did not take place in 57.8 ± 0.6% eimerias oocysts, 2.7 ± 0.9% oocysts completed sporulation and 19.6 ± 0.9 % — the sporulation was delayed. The best results were obtained with the use of a 3% solution at an exposure of 5 and 8 hours. The sporogony process did not occur in 96.6 ± 1.2% and 98.2 ± 0.8% of oocysts of eimerias. When using “Brovadez-plus” disinfectant at a concentration of 3.5% at exposure for 3 hours sporogonia did not pass in 78.5 ± 1.1% of eimerias oocysts, at exposure for 5 hours in 96.8 ± 2.1% of eimerias oocysts at exposure 8 hours in 99.1 ± 2.4% of eimerias oocysts of calves. Thus, experimental studies have shown that the drug “Brovadez-plus”, when used in 3% and 3.5% concentrations, has a high level of disinvasive properties relative to eimerias oocysts of calves. Experimental studies have established that the detrimental effect on eimerias oocysts is directly proportional to the duration of their contact and the concentration of the working solution of the studied drug. When using 3% and 3.5% concentrations of “Brovades-plus” disinfectant at an exposure of 5 and 8 hours in 99.1 ± 2.4% of eimerias oocysts of calves, the process of sporogony did not occur

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Research of the Activity of Disinfectants to Microorganisms Isolated From Pathological Poultry Material

Kushnir,

Berbeka,

Gufriy

et al. 2024

SCIVP

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Disinfectants should have low toxicity and allergenicity, have good solubility in water or easily form suspensions, emulsions in it, act quickly and in small concentrations, be sufficiently stable during storage and environmentally safe. An important characteristic of each disinfectant should also be a wide spectrum of antimicrobial action on microorganisms. Therefore, the sensitivity of strains of microorganisms isolated from pathological poultry material to disinfectants was studied. During the identification of cultures isolated from the pathological material of poultry, six isolates of Essherichia coli and three isolates of Salmonella enteritidis were isolated. Four disinfectants were used for the study, which included alkyldimethylbenzylammonium chloride and glutaraldehyde (sample №1), didecyldimethylammonium bromide (sample №2), polyhexamethylenebiguanidine hydrochloride (sample №3), and peracetic acid (sample № 4). It was established that out of six isolates E. coli isolated from the pathological material, one was resistant to the disinfectant based on polyhexamethylenebiguanidine hydrochloride, which was 16,7 % and out of three S. enteritidis isolates, two isolates were 66,7 %. Three out of six E. coli isolates were resistant to the disinfectant based on peracetic acid, which was 50 %, and one isolate was resistant out of three S. enteritidis isolates, which was 33,3 %.

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Disinfection and environment

Cited by 3 publications

References 5 publications

Retrospective analysis of production of main active ingredients and assortment of disinfectants in Ukraine

Retrospective analysis of production of main active ingredients and assortment of disinfectants in Ukraine

Influence of “Brovadez-plus” disinfectant in different concentrations on Eimeria oocysts in calves

Research of the Activity of Disinfectants to Microorganisms Isolated From Pathological Poultry Material

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