Disseminated American Cutaneous Leishmaniasis

Abstract

Diffuse cutaneous leishmaniasis can be caused also by Leishmania venezuelensis. Patients with nodular lesions who presented a negative Montenegro skin test were more resistant to treatment with specific pentavalent antimonials.

Ecology of the Leishmania Species in the Guianan Ecoregion Complex

“…23,43 Interestingly, DCL was also shown to be caused by L. (L.) venezuelensis but not strictly in the GEC. 52 Mucocutaneous leishmaniasis. Mucocutaneous leishmaniasis is also widespread in Brazil.…”

Leishmania species identification using FTA card sampling directly from patients’ cutaneous lesions in the state of Lara, Venezuela

“…8 Cutaneous leishmaniasis (CL) is endemic in the state of Lara located in western 4 Venezuela, and the causative parasites have been identified as Leishmania (Viannia) braziliensis and Leishmania (Leishmania) venezuelensis. [9][10][11][12] L. (L.) venezuelensis was originally described on the basis of distinguishable MLEE patterns as a species independent of other members of the L. mexicana complex 9,10 . Further, a serodeme-based analysis using a panel of monoclonal antibodies was performed to Here, a molecular epidemiological study was performed by using FTA card materials directly sampled from lesions of patients with CL in the state of Lara, Venezuela, and the causative species for CL in this area were genetically characterized.…”

Diffuse cutaneous leishmaniasis associated with the immune reconstitution inflammatory syndrome

“…The parasite load in these lesions is enormous. Areas most commonly affected include the face, upper and lower extremities, and buttocks 9,35,46,47 . Less often, the genitalia and trunk are involved; the scalp and axillae are spared 33,35 .…”

“…Areas most commonly affected include the face, upper and lower extremities, and buttocks. 9,35,46,47 Less often, the genitalia and trunk are involved; the scalp and axillae are spared. 33,35 Involvement of the face and ears imparts characteristic leonine facies, which is strikingly similar to lepromatous leprosy.…”

“…48 Infiltration of lymphatic vessels by leishmania protozoa resembles sporotrichosis. DCL can be clinically indistinguishable from lepromatous leprosy or Jorge Lobo's disease (a chronic deep mycotic infection caused by Lacazia loboi ): 46 cultures and histologic staining differentiate the two, and nerve involvement is not seen. The lesions of DCL may also resemble cutaneous lymphoma.…”