“…The case study was defined to illustrate the application of the uncertainty and sensitivity methodology to a continuous distillation process. The methanol-water system was selected because of its industrial relevance (Abolpour et al, 2013;Biddulph and Kalbassi, 1988;Shahandeh et al, 2015;Yang et al, 2003). Table 1 shows the deterministic values of the specific feed stream used and the targeted compositions of the top and bottom products in terms of the molar fraction of the light key component (methanol).…”