Distribution and human health risk assessment of antibiotic residues in large-scale drinking water sources in Chongqing area of the Yangtze River

Feng, Liang; Yanru, Cheng; Zhang, Yiyi; Li, Ziwei; Yu, Yichang; Feng, Lei; Zhang, Sheng; Xu, Linji

doi:10.1016/j.envres.2020.109386

Cited by 109 publications

(31 citation statements)

References 27 publications

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“…As a key factor, pH affects the degree of dissociation of the substances in solution and the electrical conductivity of the solution; furthermore, pH affects the formation rate, yield, and hydrogen and oxygen evolution of strong oxidizing intermediates, all of which affect the electrochemical reaction rate. To explore the influence of solution pH on the removal of oxytetracycline, experiments were carried out with different pH (3,5,7,9), while other conditions (current: 0.4 A, Na 2 SO 4 electrolyte concentration: 4 g/L, plate spacing: 2 cm) remained unchanged. As shown in Figure 2, the rate of oxytetracycline removal increased gradually with decreasing pH, and increased significantly when the pH of the solution gradually became acidic.…”

Section: Factors Influencing the Degradation Effect Of Oxytetracyclinementioning

confidence: 99%

“…Microorganisms in the water can become resistant to the added antibiotics after long-term exposure to them in the environment, affecting the microbial community and aquatic organisms and destroying the aquatic ecosystem [7,8]. Additionally, antibiotics from various sources are eventually transported to water bodies, seep into groundwater, and contaminate drinking and tap water [9]. In addition, antibiotics remaining in water bodies and deposited in sediment re-enter the soil through irrigation and sludge fertilization and are absorbed into the food chain by microorganisms, algae, and crops.…”

Section: Introductionmentioning

confidence: 99%

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Study on the Electrochemical Removal Mechanism of Oxytetracycline by a Ti/IrO2-Ta2O5 Plate

Zhang

Jiang

et al. 2021

IJERPH

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In this study, a Ti/IrO2-Ta2O5 anode was prepared by a hydrothermal method, and the prepared electrode was characterized by techniques such as scanning electron microscopy, X-ray diffraction, and electron dispersive spectroscopy. At the same time, the anode characteristics before and after electrochemical experiments were analyzed. The electrode gradation mechanism of oxytetracycline is discussed. In the whole experimental process, the range of electrolysis conditions was determined by single factor experiment, and then the optimal removal condition of oxytetracycline was determined by orthogonal experiments. The removal rate of oxytetracycline reached 99.02% after 20 min of electrolysis under the following optimal conditions: a current of 0.500 A, plate spacing of 2 cm, Na2SO4 electrolyte concentration of 4 g/L, and solution pH of 3. Additionally, the mechanism of oxytetracycline removal was explored, free radical scavenging experiments were performed, and the degradation mechanism was inferred based on the changes in the ultraviolet absorption of the oxytetracycline solution before and after electrolysis. Then, based on the liquid chromatography–mass spectrometry data, seven possible compounds and five possible removal pathways were proposed.

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Section: Factors Influencing the Degradation Effect Of Oxytetracyclinementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Study on the Electrochemical Removal Mechanism of Oxytetracycline by a Ti/IrO2-Ta2O5 Plate

Zhang

Jiang

et al. 2021

IJERPH

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“…Therefore, the occurrence of pharmaceuticals in drinking water sources and tap water might pose health concern and water management challenge. Most previous studies focused on the distribution and potential risk assessment of pharmaceuticals in drinking water sources and tap water in the city in the upper or lower reaches of the Yangtze River, such as Chongqing (Feng et al 2020), Nanjing (Liu et al 2020), andShanghai (Liu et al 2019;Wen et al 2014). However, information on the occurrence of pharmaceuticals in drinking water system in the city in the middle reaches of the Yangtze River is limited.…”

Section: Introductionmentioning

confidence: 99%

Pharmaceuticals in drinking water sources and tap water in a city in the middle reaches of the Yangtze River: occurrence, spatiotemporal distribution, and risk assessment

Peng³

et al. 2021

Environ Sci Pollut Res

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The occurrence of ten target pharmaceuticals was investigated in drinking water sources and tap water in a city in the middle reaches of the Yangtze River, including erythromycin (ERY), roxithromycin (RTM), ciprofloxacin (CPX), ofloxacin (OFX), sulfadiazine (SDZ), sulfamethoxazole (SMX), oxytetracycline (OTC), tetracycline (TC), ibuprofen (IBF), and naproxen (NPX). And the corresponding ecological risk for three classes of aquatic organisms and human health risk for different life stages were estimated. Results demonstrated that nine pharmaceuticals except for TC were detected with the frequencies of 20-100% and the concentrations of

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“…Various antibiotics have stable structures and have harmful toxic effect and due to which non-biodegradable parts of such antibiotics are directly discharged into a variety of environmental compartments which leads to health hazards to human . Antibiotic use is huge, despite the lack of o cial survey data on the detailed use of various types of antibiotics (Feng et al 2020).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antibiotic Residue in Cow Milk and Its Impact on Danio Rerio

Chowdhury

Mukherjee

Dutta

et al. 2021

Preprint

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Ceftriaxone (CEFT), a widely used wide-spectrum beta -lactam cephalosporin antibiotic, is used to treat bovine mastitis, which is caused by a variety of bacteria. When this antibiotic is used injudiciously, it leaves a residue that persists after pasteurization. Antibiotic residue contamination occurs when antibiotic residue exceeds its Maximum Residue Limits (MRLs).This has a negative impact on both public health and the environment. The aim of a recent study was to determine the concentration of ceftriaxone residue (CEFTR) in raw and pasteurized mastitis cow milk, as well as its role in developmental toxicity and genotoxicity in zebra fish model. CEFTR concentrations in raw and pasteurized milk were several times higher than CEFT's MRL. CEFTR showed a decrease in body length and yolk sac region of zebra fish larvae 7-amino cephalosporanic acid (7-ACA), C3 and C7 are the cephalosporin constituents that produced by the breakdown of CEFT that may present in CEFTR, have an impact on the zebra fish embryo in this stage of development. Comet Assay or single cell gel electrophoresis (SCGE) also exhibited highest percentage of tail DNA, and tail moment that is the ultimate indicator of DNA damage by breaking DNA strands and incorporating guanine residue in the genome that ultimately damages DNA. As a result, the CEFTR is extremely concerning for public health and the environment. The toxic effects of the CEFTR in zebra fish model have not been studied yet. This is the first comprehensive study.

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Distribution and human health risk assessment of antibiotic residues in large-scale drinking water sources in Chongqing area of the Yangtze River

Cited by 109 publications

References 27 publications

Study on the Electrochemical Removal Mechanism of Oxytetracycline by a Ti/IrO2-Ta2O5 Plate

Study on the Electrochemical Removal Mechanism of Oxytetracycline by a Ti/IrO2-Ta2O5 Plate

Pharmaceuticals in drinking water sources and tap water in a city in the middle reaches of the Yangtze River: occurrence, spatiotemporal distribution, and risk assessment

Evaluation of Antibiotic Residue in Cow Milk and Its Impact on Danio Rerio

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