Do Blood Group Antigens and the Red Cell Membrane Influence Human Immunodeficiency Virus Infection?

Davison, Glenda Mary; Hendrickse, Heather L.; Matsha, Tandi E.

doi:10.3390/cells9040845

Cited by 21 publications

(33 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In fact, genetic factors play an important role in many diseases, such as cardiovascular diseases [ 11 ], diabetes mellitus [ 12 ], cancers [ 13 ] and infectious diseases, including malaria [ 14 ], HIV and influenza [ 15 , 16 ]. As a genetic factor, the ABO blood type distribution has been extensively investigated in the field of infectious diseases [ 15 – 17 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Association between the dynamics of the COVID-19 epidemic and ABO blood type distribution

et al. 2021

View full text Add to dashboard Cite

The coronavirus disease 2019 (COVID-19) pandemic is currently the most critical challenge in public health. An understanding of the factors that affect severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection will help fight the COVID-19 pandemic. This study sought to investigate the association between SARS-CoV-2 infection and blood type distribution. The big data provided by the World Health Organization (WHO) and Johns Hopkins University were used to assess the dynamics of the COVID-19 epidemic. The infection data in the early phase of the pandemic from six countries in each of six geographic zones divided according to the WHO were used, representing approximately 5.4 billion people around the globe. We calculated the infection growth factor, doubling times of infection and death cases, reproductive number and infection and death cases in relation to the blood type distribution. The growth factor of infection and death cases significantly and positively correlated with the proportion of the population with blood type A and negatively correlated with the proportion of the population with blood type B. Compared with the lower blood type A population (<30%), the higher blood type A population (⩾30%) showed more infection and death cases, higher growth factors and shorter case doubling times for infections and deaths and thus higher epidemic dynamics. Thus, an association exists between SARS-CoV-2 and the ABO blood group distribution, which might be useful for fighting the COVID-19 pandemic.

show abstract

Section: Discussionmentioning

confidence: 99%

“…and influenza [15,16]. As a genetic factor, the ABO blood type distribution has been extensively investigated in the field of infectious diseases [15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Association between the dynamics of the COVID-19 epidemic and ABO blood type distribution

et al. 2021

View full text Add to dashboard Cite

show abstract

“…On the other hand, the perception that individual blood group O positive protect the trial participants from HIV infection lacks scientific evidence. Anecdotal evidence has shown that blood cell antigens and rhesus factor C have influence and interaction with HIV [ 60 , 61 , 62 ]. This is a novel and interesting area to be investigated in the future.…”

Section: Discussionmentioning

confidence: 99%

Sexual Behaviours and Practices before and after Phase I/II HIV Vaccine Trial: A Qualitative Study among Volunteers in Dar es Salaam Tanzania

Iseselo

Tarimo

Sandström

et al. 2020

IJERPH

View full text Add to dashboard Cite

There is limited information about sexual behavior among volunteers who participated in phase I/II human immunodeficiency virus (HIV) vaccine trial. This article describes the sexual behavior, practices before, and after participation in phase I/II HIV vaccine trial in Dar es Salaam, Tanzania. We conducted a qualitative descriptive study involving volunteers who participated in the phase I/II vaccine trial between 2007 and 2010. Purposeful sampling was used to recruit potential informants. Twenty-four in-depth interviews were conducted. The audio-recorded interviews were transcribed verbatim and analyzed using a thematic content analysis approach. The findings revealed that before participation in the HIV vaccine trial, informants were engaging in unprotected multiple sexual relationships. After the completion of the HIV vaccine trial, informants reported strengthened marital relationships, increased understanding of safer sexual practices, and HIV testing. However, the informants reported challenges regarding vaccine-induced seropositivity that adversely affected their sexual and marital relationships. Some informants re-engaged in risky sexual practices because they perceived the experimental vaccine was protective. The informants suggested having continued interventions within the community to enhance safer sexual practices. Participation in phase I/II HIV vaccine trials may positively and negatively influence changes in volunteers’ sexual behaviors and practices. The trial interventions appear to improve compliance with safer sexual practices. However, the reported vaccine-induced seropositivity and the perception that experimental vaccines are protective need further appropriate interventions.

show abstract

“…Discussion ABO blood group system is a very stable genetic material, which is located in the long arm three region four band (9q34) of chromosome 9. It is closely related to many disease [8,13,14]Davison Glenda M, et al [15] considered the expression of blood group antigens varies across human populations and geographical regions due to natural selection and the in uence of environment factors and disease. The red cell membrane is host to numerous surface antigens which are able to in uence susceptibility to disease.…”

Section: Covid-19 Infected Risk Factorsmentioning

confidence: 99%

Distribution of ABO blood groups and association to low risk of COVID-19 infection in patients

Peng

Huang

Zhu

et al. 2020

Preprint

View full text Add to dashboard Cite

Background Since December 2019, the novel coronavirus pandemic (COVID-19) has become a global health emergency. To date, studies on the correlation between ABO blood groups and COVID-19 infected risk had rarely reported. This study aimed to describe the ABO blood groups distribution and association to low risk of COVID-19 infection for effectively concerning about the susceptible population. Methods We included 138 COVID-19 diagnosed patients and 82 non- COVID-19 patients between January 21 and February 20, 2020.We compared ABO blood group distribution, gender distribution and correlation analysis in Severe, Non-severe and Non-COVID19 patients, and analyzed the laboratory indexes of type O and non-type O groups in COVID19 patients. Results The laboratory results were significantly difference between type O and non-type O COVID19 patients (P < 0.05). Patients with blood type O had lower risk of severe COVID-19 infection (χ2 = 4.066, p = 0.044, OR = 0.380), and especially, female with the type O blood had lower risk in deteriorating severe COVID19 infection (p = 0.049). Conclusion Patients with the blood group of type O had relatively lower risk of COVID19 infection, especially, female with the type O blood had lower risk in deteriorating severe COVID19 infection. We should concern more to the patients with non-type O blood to minimize the risk of COVID19 infection.

show abstract

Do Blood Group Antigens and the Red Cell Membrane Influence Human Immunodeficiency Virus Infection?

Cited by 21 publications

References 52 publications

Association between the dynamics of the COVID-19 epidemic and ABO blood type distribution

Association between the dynamics of the COVID-19 epidemic and ABO blood type distribution

Sexual Behaviours and Practices before and after Phase I/II HIV Vaccine Trial: A Qualitative Study among Volunteers in Dar es Salaam Tanzania

Distribution of ABO blood groups and association to low risk of COVID-19 infection in patients

Contact Info

Product

Resources

About