Do Depression and Educational Attainment Mediate the Association between Ethnicity and Dementia?

Momtaz, Yadollah Abolfathi; Hamid, Tengku Aizan; Yusoff, Suraya; Ibrahim, Rahimah

doi:10.1159/000342254

Cited by 12 publications

(10 citation statements)

References 35 publications

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“…As expected, in concordance with previous studies, the findings from this study showed statistically significant association between dementia and age, 3 sex, 21 marital status, 22 educational attainment, 15 ethnicity, 4 and stratum. 23 …”

Section: Discussionsupporting

confidence: 93%

“…Validation of the Malaysian version of GMS-AGECAT against clinical assessment of dementia revealed an overall agreement of 76.2% (n=105) with a moderate kappa value of 0.502. 4 The GMS-AGECAT has been widely used and applied with good levels of agreement in a variety of settings. The scores of 3 or higher on the GMS-AGECAT were considered as dementia.…”

Section: Methodsmentioning

confidence: 99%

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Does food insufficiency in childhood contribute to dementia in later life?

Momtaz

Haron

Hamid

et al. 2014

CIA

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BackgroundDespite several studies attempting to identify the risk factors for dementia, little is known about the impact of childhood living conditions on cognitive function in later life. The present study aims to examine the unique contribution of food insufficiency in childhood to dementia in old age.MethodsData for this study of 2,745 older Malaysians aged 60 years and older was obtained from a national survey entitled “Mental Health and Quality of Life of Older Malaysians” conducted from 2003 through 2005 using a cross-sectional design. The Geriatric Mental State-Automated Geriatric Examination for Computer Assisted Taxonomy was used to measure dementia. A multiple binary logistic regression using Statistical Package for Social Sciences version 21 was conducted to assess the unique effect of food insufficiency in childhood on developing dementia in old age.ResultsA notably higher prevalence of dementia was found in respondents who indicated they had experienced food insufficiency in childhood than in their food-sufficient counterparts (23.5% versus 14.3%). The findings from multiple logistic regression analysis revealed that food insufficiency in childhood would independently increase the risk of developing dementia in old age by 81%, after adjusting for sociodemographic factors (odds ratio =1.81, 95% confidence interval 1.13–2.92, P<0.01).ConclusionFindings from the present study showing that food insufficiency in early life significantly contributes to dementia in later life highlight the importance of childhood living conditions in maintaining cognitive function in old age. It is, therefore, suggested that older adults with childhood food insufficiency might be targeted for programs designed to prevent dementia.

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Section: Discussionsupporting

confidence: 93%

Section: Methodsmentioning

confidence: 99%

Does food insufficiency in childhood contribute to dementia in later life?

Momtaz

Haron

Hamid

et al. 2014

CIA

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“…Socio-demographic confounding factors contributing to cognitive function [26,27], such as age, sex, marital status, years of education, household income, and employment status were assessed.…”

Section: Confounding Factorsmentioning

confidence: 99%

The Association Between Diabetes and Cognitive Function in Later Life

Momtaz

Hamid

Bagat

et al. 2019

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Introduction: Although diabetes through several possible mechanisms such as increased microvascular pathology and inefficiency of glucose utilization during cognitive tasks can be associated with cognitive impairment, there is inconclusive evidence that shows elderly diabetic patients under therapy have higher cognitive function compared to their non-diabetics counterparts. The present study was conducted to elucidate the association between diabetes and cognitive function in later life. Methods: Data for this study, consisting of 2202 older adults aged 60 years and above, were taken from a population-based survey entitled “Identifying Psychosocial and Identifying Economic Risk Factor of Cognitive Impairment among Elderly. Data analysis was conducted using the IBM SPSS Version 23.0. Results: The mean of MMSE was found to be 22.67 (SD = 4.93). The overall prevalence of selfreported diabetes was found to be 23.6% (CI95%: 21.8% - 25.4%). The result of independent t-test showed diabetic subjects had a higher mean score of MMSE (M = 23.05, SD =4 .55) than their counterparts without diabetes (M = 22.55, SD = 5.04) (t = -2.13 p<.05). The results of multiple linear regression analysis showed that diabetes was not significantly associated with cognitive function, after controlling the possible confounding factors. Conclusions: The findings from the current study revealed that diabetes is not associated with cognitive decline. This study supports the findings that long-term treatment of diabetes may reduce the risk of cognitive decline. This finding may provide new opportunities for the prevention and management of cognitive decline.

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“…We included data on birth place, which is an important key indicator of socioeconomic status disparities and possibly of genetic predisposition. In addition, previous studies suggest that risk of cognitive impairment differs between Israeli-born and immigrants populations [24,25]. Physical activity was assessed by asking participants "Do you participate in one or more of the following activities such as walking, swimming, jogging, gymnastics, biking, dancing, tennis, gardening and rehabilitation activities" and "How many times per week do you engage in physical activity".…”

Section: Baseline Laboratory Measurementsmentioning

confidence: 99%