Does Migraine-Associated Vertigo Share a Common Pathophysiology With Meniere's Disease? Study With Vestibular-Evoked Myogenic Potential

Murofushi, Toshihisa; Ozeki, Hidenori; Inoue, A.; Sakata, Aki

doi:10.1111/j.1468-2982.2009.01860.x

Cited by 88 publications

(65 citation statements)

References 35 publications

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“…White-noise masking (40 dB nHL) was performed in the contralateral ear. Before the ABR test was performed, all the patients were subjected to pre-cleaning of the skin and attachment of disposable electrodes in the frontopolar region (Fpz) and right and left mastoids (M1 and M2), in accordance with the norms of the International Electrode System (IES [10][11][12][13][14][15][16][17][18][19][20]. The electrode impedance was <5 kΩ.…”

Section: Methodsmentioning

confidence: 99%

“…In recent years, many studies have been published regarding cVEMP responses in migraine; although some studies describe normal cVEMP responses and decreased amplitudes [14][15][16][17] , others report delayed or nonexistent cVEMP responses [18][19][20][21] . Vestibular migraine (VM) is known as migrainous vertigo/dizziness, migraine-related vestibulopathy, and migraine-associated dizziness or vertigo.…”

Section: Introductionmentioning

confidence: 99%

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Correlation between cVEMP and ABR for the Evaluation of Vestibular Migraine

Sürmeli

Sürmeli²,

Deveci³

et al. 2016

Int Adv Otol

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In this study, we aimed to determine the characteristics of the cVEMP and ABR responses of patients with VM and migraine in contrast to healthy controls. In this study, cVEMP and ABR changes during the VM attack period were compared with the cVEMP and OBJECTIVE: Vestibular migraine (VM) is a clinical condition characterized by temporal overlap between vestibular symptoms and migraine. In this study, we aimed to determine the changes in vestibular myogenic potential (cVEMP) and auditory brainstem response (ABR) in patients with VM and migraine. MATERIALS and METHODS:A total of 86 participants with no hearing loss or additional disease between the ages of 18 and 45 were enrolled in three different groups: group 1, VM; group 2, migraine without aura; and group 3, healthy controls. cVEMP and ABR were performed for all participants during attacks and attack-free periods. The differences between the right and left sides were calculated. RESULTS:There was no significant difference in cVEMP p13-n23 latencies between any of the groups. There were statistically significant differences related to cVEMP p13-n23 amplitudes between groups 1, 2, and 3. This significant difference originated from group 1 when compared with the other groups (p<0.05). When we compared the cVEMP results of patients with VM during attack and attack-free periods, a statistically significant decrease was determined in the p13-n23 amplitude values during the attack period (p<0.01). Additionally, when we compared group 1 and group 3, the wave V peak latencies in ABR were significantly prolonged in group 1 (p<0.05).CONCLUSION: cVEMP and ABR can be used as diagnostic criteria for patients with VM during attacks. Further studies with larger groups are needed to verify our findings.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Correlation between cVEMP and ABR for the Evaluation of Vestibular Migraine

Sürmeli

Sürmeli²,

Deveci³

et al. 2016

Int Adv Otol

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“…Rauch et al [2004] were the first to demonstrate that VEMP tuning could be altered by pathology that affects the mechanics of the inner ear. Instead of demonstrating optimal responses at 500 Hz, as is the trend for most control subjects, patients with Ménière's disease exhibited higher amplitudes and lower thresholds at a frequency of 1 kHz Lin et al, 2006;Murofushi et al, 2009;Kim-Lee et al, 2009;Winters et al, 2011]. This upward shift in resonance was attributed to the presence of endolymphatic hydrops in the otolith organs, causing an increase in stiffness .…”

Section: Introductionmentioning

confidence: 94%

Tuning Characteristics of Ocular and Cervical Vestibular Evoked Myogenic Potentials in Intact and Dehiscent Ears

Taylor¹,

Bradshaw²,

Halmagyi³

et al. 2012

Audiol Neurotol

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Cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs) to air-conducted tone bursts (250–2000 Hz) were recorded in 14 patients with superior canal dehiscence (SCD) and 32 healthy controls. For cVEMPs, the most common ‘optimal frequency’ in control ears (48.2%) was 500 Hz; for oVEMPs, it was 1000 Hz (51.8%). We found a significant interaction between age and frequency, with a shift towards higher-frequency tuning in older subjects. cVEMP and oVEMP tuning in SCD was characterised by a broadening of amplitude and threshold tuning curves. The tendency of cVEMPs to tune to lower frequencies compared to oVEMP was enhanced in SCD. Differences in cVEMP and oVEMP ‘optimal frequencies’, demonstrated in 57.1% intact ears and 81.3% dehiscent ears, imply differences in the recruitment of hair cells generating these two reflexes. Age-matched oVEMP amplitudes provided excellent separation between SCD and control ears. Although cVEMP amplitudes overlapped between SCD and control ears, better separation was achieved by using a 2-kHz stimulus.

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“…Headache was a sole cue to suspect diseases in the central nervous system. Nowadays, attention has been paid to VM as one of common clinical entities of vertigo [5,6]. However, prior to diagnosis of VM, vertigo associated with secondary headache must be excluded.…”

Section: Discussionmentioning

confidence: 99%

A case of cerebellar arteriovenous malformation presented with vertigo, hearing loss, and headache

Komiyama

Murofushi

Yoshimura³

2017

Acta Oto-Laryngologica Case Reports

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We report a 48-year-old man presented with episodic rotatory vertigo accompanied by right hearing loss and headache. He did not have medical history of migraine. His hearing loss was progressive. He showed unilateral (right-sided) absence of cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP) to the right ear stimulation, while his caloric tests were normal on both sides. His signs and symptoms were suggestive of right peripheral vestibular vertigo except for headache. MRI revealed cerebellar arteriovenous malformation (AVM). Headache might be a sole cue for correct diagnosis. On the diagnosis of vertigo patients with headache, vertigo associated with secondary headache must be considered. ARTICLE HISTORY

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Does Migraine-Associated Vertigo Share a Common Pathophysiology With Meniere's Disease? Study With Vestibular-Evoked Myogenic Potential

Cited by 88 publications

References 35 publications

Correlation between cVEMP and ABR for the Evaluation of Vestibular Migraine

Correlation between cVEMP and ABR for the Evaluation of Vestibular Migraine

Tuning Characteristics of Ocular and Cervical Vestibular Evoked Myogenic Potentials in Intact and Dehiscent Ears

A case of cerebellar arteriovenous malformation presented with vertigo, hearing loss, and headache

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