Does platelet-rich plasma decrease time to return to sports in acute muscle tear? A randomized controlled trial

Endometrium is one of the main factors in pregnancy. During assisted reproductive technology (ART) treatments, some cycles are cancelled due to inadequate endometrial growth. This study was conducted to evaluate the effectiveness of platelet-rich plasma (PRP) in the treatment of thin endometrium. Ten patients with history of inadequate endometrial growth in frozen-thawed embryo transfer (FET) cycles were recruited into the study. Intrauterine infusion of PRP was performed. Endometrial thickness was assessed. Chemical and clinical pregnancies were reported. In all patients, endometrial thickness increased after PRP and embryo transfer was done in all of them. Five patients were pregnant. According to this study, it seems that PRP was effective for endometrial growth in patient with thin endometrium.

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“…, 2016; Lee et al. , 2016; Maria-Angeliki et al , 2015; Picard et al , 2015; Ronci et al , 2015; Rossi et al , 2016; Sadabad et al , 2016). …”

Section: Introductionunclassified

Treatment of thin endometrium with autologous platelet-rich plasma: a pilot study

Zadehmodarres

Salehpour

Saharkhiz

et al. 2017

JBRA Assisted Reproduction

161

132

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“…Platelet-rich plasma is an orthobiologic that has recently gained popularity as an adjuvant treatment for musculoskeletal injuries [10][11][12][13][14][15][16][17][18]. It is a volume of fractionated plasma from the patient's own blood that contains platelet concentrate.…”

Section: Spine Research Issn 2471-8173mentioning

confidence: 99%

“…The role of PRP in the directed stimulation of musculoskeletal and mesenchymal stem cells is being widely investigated and shows promise as a short-term use agent that may assist in the simultaneous healing of several musculoskeletal tissues with trauma or elective surgery [6,[14][15][16].…”

Section: Spine Research Issn 2471-8173mentioning

confidence: 99%

Autologous Platelet Rich Plasma for Neck and Lower Back Pain Secondary to Spinal Disc Herniation: Midterm Results

Cameron¹,

Thielen²

2017

Spine Res

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“…It is collected from peripheral veins and contains several growth factors such as vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), platelet derived growth factor (PDGF), transforming growth factor (TGF) and other cytokines that stimulate proliferation and growth. Recently, PRP has been used in several medical conditions in ophthalmology, orthopedics, surgery and wound healing but it's efficacy in endometrial growth has not been fully elucidated [6,7,8,9,10,11,12] .…”

Section: Original Introductionmentioning

confidence: 99%

PRP in recurrent implantation failure, hope or hype? A Prospective randomized controlled study

Rageh

Barakat

Ahmed

et al. 2020

Evidence Based Women's Health Journal

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Introduction:The endometrial function and endometrial receptivity have been accepted to be major limiting factors in the establishment of pregnancy. In spite of improved almost all aspects of IVF: ovarian stimulation, embryo culture and transfer, the pregnancy rates still not satisfactory. The bottleneck is the process of implantation. Recurrent implantation failure (RIF) is one of the nightmares in reproductive medicine and despite several strategies that have been described for management; there is no universal agreement yet. Recently, intrauterine infusion of platelet-rich plasma (PRP) is described to promote endometrial growth and receptivity, PRP has been investigated as a therapeutic approach for several medical disorders in dermatology and rheumatology, but its use in IVF is still limited. Aim: To evaluate the effectiveness of intrauterine perfusion of autologous platelet-rich plasma in improvement of pregnancy rate in RIF patients. Design: Prospective randomized controlled study. Patients and Methods: After ethical committee approval was obtained, 150 infertile women with history of RIF gave their consent to be included in this study, with age below 40 yrs, body mass index (BMI) below 30 kg/m2. They were divided into 2 comparable groups ; all participants underwent antagonist protocol. In the study group, intrauterine infusion of (PRP) was performed 48 hrs before blastocyst transfer, pregnancy tests were done 12 days after ET. Results: Out of 75 participants in each group, 32 got pregnant (43%) in the study group, compared to 11 pregnant participants (15%) in control group. Conclusion: According to our study, PRP significantly improved the pregnancy rate and may be a new hope in RIF patients.

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Does platelet-rich plasma decrease time to return to sports in acute muscle tear? A randomized controlled trial

Abstract: I.

Cited by 87 publications

References 31 publications

Treatment of thin endometrium with autologous platelet-rich plasma: a pilot study

Treatment of thin endometrium with autologous platelet-rich plasma: a pilot study

Autologous Platelet Rich Plasma for Neck and Lower Back Pain Secondary to Spinal Disc Herniation: Midterm Results

PRP in recurrent implantation failure, hope or hype? A Prospective randomized controlled study

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