Doppler Ultrasonography of the Ophthalmic and Central Retinal Vessels

Guthoff, Rudolf; Berger, R. W.; Winkler, Peter; Helmke, K.; Chumbley, L.

doi:10.1001/archopht.1991.01080040100037

Cited by 203 publications

(98 citation statements)

References 7 publications

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“…We excluded these patients to focus on the effect of diabetes on orbital blood flow in type 2 diabetic patients. An experimental study by Guthoff et al has shown that an increase in intraorbital pressure leads to a decrease in central retinal artery flow [30]. Great care was thus taken to apply as little pressure as possible to the patient's eye during color Doppler imaging examination.…”

Section: Discussionmentioning

confidence: 99%

Orbital Doppler Evaluation of Blood Flow Velocities in Patients with Diabetic Retinopathy

Karami

Janghorbani²,

Dehghani³

et al. 2012

Rev Diabet Stud

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■ Abstract BACKGROUND:There have been conflicting results in relation to impaired ocular hemodynamics in the orbital vessels of patients with diabetic retinopathy (DR). Clarification of the early signs of retinopathy in diabetic patients is urgently needed. AIMS: We aimed to evaluate orbital blood flow velocities using Doppler and gray-scale sonography in patients with DR, and to compare the results with those of their non-diabetic and diabetic peers without retinopathy. METHODS: Orbital Doppler and gray-scale sonography were performed in 123 patients aged 29-77 who had been divided into 3 groups: non-diabetic controls (n = 25), diabetes and impaired glucose tolerance with minimal clinical retinopathy (n = 74), and diabetes with untreated nonproliferative retinopathy (n = 24). Retinopathy was diagnosed by an ophthalmologist on the basis of fundoscopic examination. The peak systolic (PSV) and end-diastolic (EDV) blood flow velocities, and the resistivity and pulsatile indices, of the ophthalmic artery, central retinal artery, posterior ciliary artery, and central retinal vein were measured. RE-SULTS: Compared with healthy controls, the age-adjusted resistivity and pulsatile indices of the ophthalmic artery were significantly higher in patients with DR (p < 0.05). PSV and EDV of the posterior ciliary arteries were significantly lower in diabetic patients with DR. After further adjustment for age, gender, HbA1c, fasting plasma glucose, blood pressure, BMI, cholesterol, HDL, LDL, and triglycerides, only the resistivity index of the ophthalmic artery and the central retinal vein remained significantly higher in patients with DR compared with healthy controls (p < 0.005 after Bonferroni adjustment). CONCLUSIONS: Resistivity index alteration of the ophthalmic artery and central retinal vein may be prevalent among patients with early changes in DR.

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Section: Discussionmentioning

confidence: 99%

Orbital Doppler Evaluation of Blood Flow Velocities in Patients with Diabetic Retinopathy

Karami

Janghorbani²,

Dehghani³

et al. 2012

Rev Diabet Stud

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“…19,20 This method makes it possible to create a colour-coded vascular map superimposed on a high-resolution B-scan image, thus allowing a quantitative and qualitative assessment of the blood flow in the area examined.…”

Section: Methodsmentioning

confidence: 99%

Optical coherence tomography, frequency-doubling technology, and colour Doppler imaging in ocular hypertension

Cellini

Bernabini

Carbonelli

et al. 2006

Eye

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Purpose To study in ocular hypertension (OH) the retinal nerve fibre layer (RNFL) with optical coherence tomography (OCT) and the neuronal function with frequency-doubling technology (FDT) to assess which of the two methods was more sensitive in detecting early glaucomatous damage. Furthermore, a colour Doppler imaging (CDI) of the optic nerve was carried out to highlight any correlation with RNFL thickness and FDT abnormality. Materials and methods We enrolled 28 ocular hypertensive patients who underwent OCT of the RNFL and FDT. Moreover, we performed a CDI of the ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary arteries (PCAs). Results The patients with OH following OCT revealed a significant thinning in the RNFL as compared to the control group only in the inferior quadrant: 122.250714.091 vs 131.750710.729 lm (Po0.045). As regards FDT, there was a significant difference between the two groups only for pattern standard deviation (PSD): 3.87371.488 vs 1.93870.704 dB (Po0.044). In OH and in the control group, CDI resistance index (RI) in the OA was 0.76870.012 vs 0.74570.019 (Po0.022), in the CRA was 0.6670.012 vs 0.64570.019 (Po0.032), and in PCAs was 0.67370.039 vs 0.62270.012 (Po0.037). The OCT had a sensitivity of 83% but only in the inferior RNFL quadrant. The FDT-PSD revealed a sensitivity of 85%. Conclusions Both FDT and OCT detect early glaucomatous damage with a slightly superior sensitivity of FDT vs OCT. The CDI measurements suggest that circulatory abnormalities may have a role in the development of OCT and FDT damage.

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“…Studies have been carried out on color Doppler imaging investigation of ocular vessels and flow measurements of the main arteries have been performed (Lieb et al 1991, Munk et al 1993, Rojanapongpun & Drance 1993, Guthoff et al 1991.…”

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confidence: 99%

Indocyanine green videoangiography and color Doppler imaging in Behçet's disease

Atmaca

Batıoğlu

1999

Acta Ophthalmologica Scandinavica

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Doppler Ultrasonography of the Ophthalmic and Central Retinal Vessels

Cited by 203 publications

References 7 publications

Orbital Doppler Evaluation of Blood Flow Velocities in Patients with Diabetic Retinopathy

Orbital Doppler Evaluation of Blood Flow Velocities in Patients with Diabetic Retinopathy

Optical coherence tomography, frequency-doubling technology, and colour Doppler imaging in ocular hypertension

Indocyanine green videoangiography and color Doppler imaging in Behçet's disease

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