Double-end readout of Lu-based scintillation pixels in Positron Emission Tomography

Fedorov, A.; Korzhik, Mikhail; Missevitch, O.; Панов, В. Н.

doi:10.1016/j.nima.2004.08.037

Cited by 4 publications

(2 citation statements)

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“…DOI determination capability was one of the most important improvements considered to be used in new generations of high resolution PETs. Possible DOI implementations include multi-layer detectors with pulse shape or logical discrimination of the hit layer, and so-called ''double-end'' readout schemes where two photodetectors compare signal amplitudes on the ends of the detector element [4]. Whereas multi-layer detectors resolve limited number of interaction coordinated along the detector element depth (generally equal to number of layers), the ''double-end'' readout schemes potentially can provide more precise information about interaction depth.…”

Section: Modern Trends In the Pet Detector Developmentmentioning

confidence: 99%

Development of scintillation materials for PET scanners

Korzhik¹,

Fedorov²,

Annenkov³

et al. 2007

Nuclear Instruments and Methods in Physics Research Section A:

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Section: Modern Trends In the Pet Detector Developmentmentioning

confidence: 99%

Development of scintillation materials for PET scanners

Korzhik¹,

Fedorov²,

Annenkov³

et al. 2007

Nuclear Instruments and Methods in Physics Research Section A:

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“…Detectors based on pixelated crystals do not intrinsically provide depth of interaction (DOI) information of the gamma ray within the pixel. However, such DOI can also be estimated with some methods, for instance using a double side readout [45]. DOI will be introduced later in section 3.3.3.…”

Section: Crystal Configurationsmentioning

confidence: 99%

Characterization of Dedicated PET Equipment with Non-Conventional Geometry

Ledo¹

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Since their introduction in the 1950-decade, tomographic images have become very valuable in the medical field helping both in diagnostics and in a variety of illnesses treatment. In the molecular imaging field, Positron Emission Tomography (PET) provides accurate information of the radio-tracers interactions with the patient tissue. Moreover, it is possible to combine this information with anatomical images provided by CT (Computed Tomography) or MR (Magnetic Resonance) scanners. With the aim to improve PET systems performance, such as the spatial resolution and the sensitivity, whole body (WB) PET scanners with large axial coverage are recently proposed. However, the system cost increases and, thus, makes difficult their installation in many hospitals or research centers. Organ-dedicated PET scanners, as an alternative to such large systems, use a lower number of detectors, so their price is considerably more economical. The goal of this kind of systems is to boost PET performance by placing the detectors as close as possible to the patient, optimizing the design for a specific organ instead of a large volume. Other advantage of these scanners is their portability. In this thesis we have worked in the design and validation of two organ-dedicated PET scanners with different geometries and technologies, as well as in a novel pre-clinical PET.The first scanner was the result from a national project called PROSPET. A PET system was designed and optimized to image the prostate area. Notice there is a high incidence rate of prostate cancer in the male population. 17% of male population will suffer prostate cancer. For this scanner, the detector modules were composed by a monolithic LYSO scintillation block coupled to a photosensor array based on silicon photomultipliers (SiPM). The first design configuration was made by two panels. However, patient results were not satisfactory due to the lack of angular information and the poor detector time resolution. Therefore, it was rebuilt in a ring configuration with a reduced diameter in comparison with WB-PET scanners. A high sensitivity and spatial resolution were found, as well as a good image quality using phantoms.The second PET scanner, called CardioPET, also arose from a national grant, and it was implemented to visualize the heart area when the patient is under stress condition. The two panels geometry was also implemented for this system, but using pixelated crystals, therefore improving the detector time resolution and allowing to use time of flight (TOF) reconstruction algorithms. Two panels were mounted and tested with both simulation and experimental data with good results. Furthermore, the patient motion was registered applying movement correction techniques with the help of an external optical camera device and ARUCO markers. These algorithms were tested showing a good performance. ivThe last device that we worked within this PhD thesis was designed to optimize the classical ring PET configuration as much as possible. To do so, the gaps between the detector mo...

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