Drug‐induced skin reaction elicited by clindamycin and penicillin: one rash, but two culprits

Pfützner, Wolfgang; Rose, Markus; Nilles, Nils

doi:10.1186/2045-7022-4-s3-p139

Cited by 4 publications

(2 citation statements)

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“…The extensive use of antimicrobial drugs produces more resistant strains, and can cause the floral imbalance in children, causing them to suffer from skin rash and antibiotic associated diarrhoea [10,11]. Recent research done in Denmark found that the systemic application of antibiotics and vaccines caused adverse reactions in every 2 out of 3 children below 2 y of age [12].…”

Section: Discussionmentioning

confidence: 99%

Clinical analysis and study of 844 children with adverse drug reactions in China

Jiao¹,

Shamsi²,

Yan³

et al. 2018

biomedicalresearch

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Objective: Retrospective clinical analysis of adverse drug reactions in children. Methods: Clinical data analysis was performed on 844 cases of hospitalized children reported for adverse drug reactions. Results: Children under 3 y of age were more prone to the adverse drug reactions; adverse reactions were mainly caused by antibiotics and traditional Chinese medicine; intravenous rout was the most common mode of administration of drug causing adverse reaction; adverse drug reaction was mostly observed within 1 h of drug administration; most common clinical manifestation of adverse drug reactions was the skin damage. Conclusions: More attention should be paid towards rational use of drugs, to avoid multiple drug use as far as possible, and to focus on prevention of adverse drug reactions, timely detection if happened and immediate treatment. Establishment of drug reaction reporting system will definitely help the physicians across the globe to better understand the phenomenon.

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Section: Discussionmentioning

confidence: 99%

Clinical analysis and study of 844 children with adverse drug reactions in China

Jiao¹,

Shamsi²,

Yan³

et al. 2018

biomedicalresearch

View full text Add to dashboard Cite

show abstract

“…6 Outside of the setting of IM, there have also been reports of clindamycin-induced AISEs in the setting of osteomyelitis and erysipelas. 7,8 There have been rare reports of Stevens-Johnson's syndrome and acute generalized exanthematous pustulosis caused by clindamycin. 3…”

Section: Discussionmentioning

confidence: 99%