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Commercially available immunoassays for vancomycin have been reported to overestimate serum vancomycin concentrations by varying degrees in patients with renal impairment, particularly those on peritoneal dialysis, by interference with crystalline degradation product-1 (CDP-1). To date this interference has not been reported in any other patient population. This report describes vancomycin fluorescence polarisation immunoassay (FPIA) interference in a patient with only mildly impaired renal function. At this time it is not possible to confirm that the interference was caused by CDP-1.

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Cited by 7 publications

References 30 publications

Comparison of high-performance liquid chromatography with fluorescence polarization immunoassay for the analysis of vancomycin in patients with chronic renal failure

Comparison of high-performance liquid chromatography with fluorescence polarization immunoassay for the analysis of vancomycin in patients with chronic renal failure

Topical Application of Eosin to Burns Produces Interference in Measurement of Serum Vancomycin by Fluorescence Polarization Immunoassay

Interference with Vancomycin Fluorescence Polarisation Immunoassay in a Nonuraemic Patient

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