Dry Eye Disease in Patients with Newly Diagnosed Depressive Disorder

Tıskaoğlu, Nesime Setge; Yazıcı, Alper; Karlıdere, Tunay; Sarı, Esin Söğütlü; Oguz, Elif Yilmaz; Musaoglu, Musa; Aslan, Seyda; Ermiş, Sıtkı Samet

doi:10.1080/02713683.2016.1236966

Cited by 40 publications

(53 citation statements)

References 18 publications

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“…Previous studies, mostly involving epidemiological questionnaires, have also reported a relationship between depression and dry eye disease [23][24][25][26]. In a comparison of depressive and control groups, one case-control study revealed significantly lower Schirmer scores and shorter TBUT, as well as a consistently higher Oxford scores in individuals with depression [27]. Similarly, we demonstrated an association between depression/anti-depressant use and dry eye severity by undertaking objective measurements, although the mechanisms involved in this association remain unknown.…”

Section: Discussionmentioning

confidence: 92%

Association of Systemic Comorbidities with Dry Eye Disease

Kawashima

Yamada

Shigeyasu

et al. 2020

JCM

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We investigated the association between dry eye disease and systemic comorbidities, including dry eye subtype, quality of life (QOL) and health utility among patients with dry eye disease. This cross-sectional, observational study enrolled 449 patients with dry eye disease (386 females; mean age, 62.6 ± 15.7 [range, 21–90] years). Ophthalmic examination findings included tear film break-up time (TBUT), Schirmer I value and keratoconjunctival staining score. QOL and health utility were evaluated using the Dry Eye-Related Quality-of-Life Score (DEQS) and Human Utility Index Mark 3 (HUI-3), respectively. Background information, including systemic comorbidities, was obtained. Prevalence of systemic comorbidities was 48.8% (219/449). No significant difference occurred between DEQS and systemic comorbidity. However, patients with dry eye disease and systemic comorbidities (depression and insomnia) exhibited significantly worse ocular surface parameters, particularly regarding TBUT, than those without. Dry eye disease with insomnia or depression comorbidity significantly correlated with friction-related diseases (including conjunctivochalasis or lid wiper epitheliopathy). A high prevalence of several systemic comorbidities occurred in patients with dry eye disease. This study shows an association between ocular signs and systemic comorbidities, particularly depression and insomnia. Ophthalmologists should be aware of patients’ systemic comorbidities in the diagnosis and management of dry eye disease.

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Section: Discussionmentioning

confidence: 92%

Association of Systemic Comorbidities with Dry Eye Disease

Kawashima

Yamada

Shigeyasu

et al. 2020

JCM

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“…28 Tiskaoglu et al also found results similar to the present study, with Schirmer's test values being significantly lower in patients diagnosed with depression compared to patients without depression. 29 However, Labbe et al, who also assessed a correlation of depression score with Schirmer test and TBUT, failed to derive a significant result. 30 Li et al also failed to find a significant correlation between depression scores and Schirmer's and TBUT scores.…”

Section: Discussionmentioning

confidence: 99%

Mental Health Status in Dry Eye Disease – a Case Control Study

Singh¹,

Singh²,

Yadav³

et al. 2018

European Ophthalmic Review

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“…But these studies only examined clinical signs of dry eye and did not reveal how this is related to eye symptoms experienced by patients. Another study found that newly-depressed and yet not medicated patients (some of them with comorbid anxiety) had more severe clinical signs of DED compared with the control group measured by objective tests, but there were no differences according to self-reported dry eye symptoms (50). However, these results are not yet fully established because other results showed the opposite (11).…”

Section: Preporuke Za Zbrinjavanje Pacijenatamentioning

confidence: 97%

Dry Eyes, Vision Problems, and Psychiatric Symptoms: Are We Missing Something?

Toth

2020

Soc psih

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Problemi vida i patologija oka često su u komorbiditetu s psihijatrijskim stanjima. Ovaj rad pruža pregled dostupnih istraživanja o takvim vezama i podiže osviješćenost o mogućem značenju i učincima različitih očnih simptoma i oštećenja vida na psihijatrijska stanja i psihičke simptome. Dodatno, psihološke karakteristike i psihijatrijska stanja razmatraju se kao mogući uzroci problema oka i vida. Većina istraživanja otkriva povezanost između problema oka i vida s psihijatrijskim stanjima i psihičkim smetnjama. Blaži oftalmološki problemi najčešće su povezani s poremećajima raspoloženja, a manje s ostalim psihijatrijskim stanjima. Ozbiljni oftalmološki problemi, poput gubitka oštrine vida, povećavaju rizik za reaktivnu depresiju. Manji broj istraživanja potvrđuje vezu između psihotičnih poremećaja i vida, koja uglavnom mijenja vidnu percepciju. Zaključno, razmotrene su moguće interakcije i odnosi između psihijatrijskih stanja i problema oka i vida te preporuke za buduća istraživanja. U preporukama za usmjeravanje i zbrinjavanje pacijenata naglašen je holistički pristup u tretmanu pacijenata. / Vision problems and eye pathology are often comorbid with psychiatric conditions. This paper provides a review of available studies about these associations and raises awareness on possible causes and impacts of different eye symptoms and vision impairment on psychiatric states and psychological symptoms. Additionally, psychological characteristics and psychiatric conditions are considered as a possible cause of eye and vision-related problems. Most of the studies found an association of eye and vision problems with psychiatric conditions and psychological disturbances. Ophthalmic problems of a milder nature are mostly associated with mood disorders and less commonly with other psychiatric conditions. Serious eye conditions, like a loss of visual acuity, increase the risk for reactive depression. Fewer studies presented a connection between psychotic disorders and vision, which mostly alters visual perception. In the concluding section, possible interactions and relationships between psychiatric conditions and eye and vision problems are presented, along with recommendations for future research. The importance of holistic professional care in patient treatment is particularly emphasized in the recommendations for patient management.

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Dry Eye Disease in Patients with Newly Diagnosed Depressive Disorder

Abstract: Our study shows a definite association between depression and DED. We feel that it is important that psychiatrists take this into account especially while prescribing antidepressants which may aggravate dry eye signs.

Cited by 40 publications

References 18 publications

Association of Systemic Comorbidities with Dry Eye Disease

Association of Systemic Comorbidities with Dry Eye Disease

Mental Health Status in Dry Eye Disease – a Case Control Study

Dry Eyes, Vision Problems, and Psychiatric Symptoms: Are We Missing Something?

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