The two-dimensional hole gas (2DHG) induced at H-terminated diamond surface provides the most widely used room-temperature surface electrical conductance of diamond semiconductors. Temperature and hole sheet density dependences of the mobility of 2DHG in H-terminated diamond are investigated for the first time considering four scattering mechanisms: surface impurity (SI) scattering, acoustic deformation potential (AC) scattering, nonpolar optical phonon (NOP) scattering, and surface/interface roughness (SFR/IFR) scattering. The calculation results are then compared with the experimental data, where the best agreement is obtained with the effective coupling constant of the non-polar optical phonon D nop and the correlation length L with values of of 1.2 Â 10 10 eV cm À1 and 2 nm, respectively. The theoretical data show that the SI scattering dominates the 2DHG mobility at a relatively large range of the temperature and the hole density due to the proximity of the surface impurities to the 2DHG, while the NOP scattering becomes important as the temperature increases further.