reported the comparison results in the range of 0-10 based on the equations. The ideal case demonstrates the highest possible level of efficiency, and lifespan, specific power and energy, energy and power density, technical maturity, and the lowest possible power and energy capital cost, self-discharge rate, and environmental impact. [13] Figure 1c represents the PCMs' characteristics.In a previous review, Sadeghi (2022), discussed the thermal energy management of batteries and high-heat-flux electronic devices, and the capability of the TES systems. [2] Costa and Kenisarin (2022) produced a database of metallic PCM's thermophysical features and potential impact in diverse fields, for instance, bioengineering, electronics, solar energy storage, cooling and heating, and beyond. [8] Chavan (2022) covered the recent progress in TES and its usages such as waste heat recovery, solar-based TES, building applications, thermal comfort, heavy electronic equipment cooling, vapor absorption refrigeration (VAR), and Heating, ventilating, and air-conditioning (HVAC) applications. [14] An increasing number of recent research addresses the use of PMCs in human body, detection or sensing, biological, barcoding, drug delivery, and medical applications. However, there is no review comprehensively discussing the life science applications of TES and PMCs materials. Based on our literature survey we concluded that a review of the life science applications of PCMs is a required reference. Besides, the evaluation and safety aspects of TES will be explored in this review. Furthermore, the challenges and recommendations of PCM applications will be addressed in order to assist energy technologists and streamline future research.