Dynamicin vitrohemocompatibility of oligoproline self-assembled monolayer surfaces

Abstract

The blood compatibility of self-assembled monolayers (SAMs) of oligoproline, a nonionic antifouling peptide, was investigated using the cone-and-plate assay imitating arterial blood flow conditions.

Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

“…For example, the work of Noguchi ad co-workers on oligo-proline SAMs demonstrated the promising capabilities of this non-ionic antifouling peptides for the development of vascular devices with ultra-low fouling properties, including reduced thrombogenic response, and low protein and cell adhesion. 142,143 Antifouling peptides have been used in combination with other peptide monolayers (mixed SAMs) for improving specificity in biosensing, and preventing biofouling formation (Table 2, peptide-SAMs antibiofouling surfaces).…”