Dyslipidemia and Cardiovascular Disease

Fakhrzadeh, Hossein; Tabatabaei‐Malazy, Ozra

doi:10.5772/30009

Cited by 7 publications

(7 citation statements)

References 91 publications

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“…Overall, CVD is caused by a combination of genetic and environmental factors like imbalanced diet, sedentary lifestyle, smoking, and social stress (Association, 2017;Bhatnagar et al, 2015). Additionally, metabolic risk factors including hyperglycemia and dyslipidemia play a dominant role in the onset and progression of CVD (Fakhrzadeh & Tabatabaei-Malazy, 2012;Levitan, Song, Ford, & Liu, 2004). Thus, CVD can be prevented through strategies that can beneficially regulate lipid profiles and glucose levels.…”

Section: Introductionmentioning

confidence: 99%

Effect of purslane on blood lipids and glucose: A systematic review and meta‐analysis of randomized controlled trials

Hadi

Pourmasoumi

Najafgholizadeh

et al. 2018

Phytotherapy Research

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Despite a history of purslane usage as a herbal treatment for dyslipidemia and hyperglycemia management, existing evidence from clinical trials is controversial. The aim for the current study was to evaluate the efficacy of purslane supplementation on lipid parameters and glycemic status in adult populations. A systematic review was conducted in PubMed, Scopus, ISI Web of Science, and Google Scholar up to January 15, 2018, searching for randomized controlled trials that assessed the impact of purslane on fasting blood glucose (FBG), triglycerides, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C).Based on the detected heterogeneity between studies, a random-or fixed-effect model was applied in the meta-analysis. The findings from six randomized controlled trials, comprising 352 participants, indicated that purslane can reduce FBG (−4.54 mg/ dl, 95% CI [−7.54, −1.53]; I 2 = 0.53%) and triglycerides ; I 2 = 0%) levels. Changes in TC, LDL-C, and HDL-C concentrations did not reach a statistically significant level. Subgroup analysis showed a favorable effects of purslane on FBG, triglycerides, TC, and LDL-C in a subset of studies in which purslane was administered >1.5 g/day. Categorization based on gender showed that purslane was more effective in improving FBG, TC and LDL-C in females compared with males. This systematic review and meta-analysis suggested that the purslane might be effective on the improvement of blood lipid and glucose levels. Further robust studies with sufficient durations and dosages of supplementation are needed to confirm these results.

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Section: Introductionmentioning

confidence: 99%

Effect of purslane on blood lipids and glucose: A systematic review and meta‐analysis of randomized controlled trials

Hadi

Pourmasoumi

Najafgholizadeh

et al. 2018

Phytotherapy Research

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“…The American Heart Association reported that 17.7 million people died from CVD in 2015, and this number is estimated to increase to around 23.6 million by 2030 (Mozaffarian et al., 2016 ). Dyslipidemia is one of the most important risk factors for CVD (Fakhrzadeh & Tabatabaei‐Malazy, 2012 ; McPherson et al, 2006 ; Rader, 2007 ). Dyslipidemia is defined by increased serum levels of triglycerides (TG), total cholesterol (TC), and low‐density lipoprotein cholesterol (LDL‐C), with reduced serum levels of high‐density lipoprotein cholesterol (HDL‐C) (Klop et al., 2013 ; Sahebkar & nutrition, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

A systematic review and meta‐analysis of the impact of cornelian cherry consumption on blood lipid profiles

Mohammadi

Sani

Nattagh‐Eshtivani

et al. 2021

Food Science & Nutrition

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“…Hence, the prevention and management of CVDs is very essential to health‐care systems (Heidenreich et al, ). Several metabolic risk factors including hyperglycemia, dyslipidemia, and hypertension are suggested that have a substantial role in the onset and progression of CVDs (Fakhrzadeh & Tabatabaei‐Malazy, ; Levitan, Song, Ford, & Liu, ; Siu, ). In this regard, pharmacological and lifestyle modification approaches are recommended to modify CVD risk factors (Alabousi et al, ; Doughty, Del Pilar, Audette, & Katz, ).…”

Section: Introductionmentioning

confidence: 99%

The efficacy of sour tea (Hibiscus sabdariffa L.) on selected cardiovascular disease risk factors: A systematic review and meta‐analysis of randomized clinical trials

Boushehri

Karimbeiki

Ghasempour

et al. 2020

Phytotherapy Research

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This study sought to summarize clinical evidence of sour tea (Hibiscus sabdariffa L.) administration on cardiovascular disease risk factors. PubMed, Scopus, Institute for Scientific Information Web of Science, and Google Scholar were systematically searched from inception to June 2019 to identify randomized clinical trials, which assessed the effect of sour tea consumption on lipid profiles, fasting plasma glucose, and blood pressure in adult populations. Mean and standard deviation for each parameter were extracted to calculate effect size. Cochrane Collaboration tools were used to evaluate risk of bias assessment. A total of seven randomized clinical trials consisting 362 participants were included in the meta-analysis. Pooled effect size demonstrated that sour tea consumption significantly reduces fasting plasma glucose (−3.67 mg/dl, 95% confidence interval, CI [−7.07, −0.27]; I 2 = 37%), systolic blood pressure (−4.71 mmHg, 95% CI [−7.87, −1.55]; I 2 = 53%), and diastolic blood pressure (−4.08 mmHg, 95% CI [−6.48, −1.67]; I 2 = 14%). Although no significant effect was observed on triacylglycerol, total cholesterol, and high-density lipoprotein cholesterolfollowing sour tea consumption, a trend toward a significant reduction was found in low-density lipoprotein cholesterol serum concentrations (p = 0.08). This systematic

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Dyslipidemia and Cardiovascular Disease

Cited by 7 publications

References 91 publications

Effect of purslane on blood lipids and glucose: A systematic review and meta‐analysis of randomized controlled trials

Effect of purslane on blood lipids and glucose: A systematic review and meta‐analysis of randomized controlled trials

A systematic review and meta‐analysis of the impact of cornelian cherry consumption on blood lipid profiles

The efficacy of sour tea (Hibiscus sabdariffa L.) on selected cardiovascular disease risk factors: A systematic review and meta‐analysis of randomized clinical trials

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