Early Differentiation Between Dengue and Septic Shock by Comparison of Admission Hemodynamic, Clinical, and Laboratory Variables

Ranjit, Suchitra; Kissoon, Niranjan; Gandhi, Deepika; Dayal, Anjul; Rajeshwari, N; Kamath, Shrishu R

doi:10.1097/01.pec.0000278403.22450.a2

Cited by 23 publications

(24 citation statements)

References 29 publications

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“…The most common age group affected in our study was 20-39 years (53%). [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] This is comparable to the study done by Neeraja et al in 2004, in Hyderabad. [18] The mean age in the present study is 30.45 years.…”

Section: Discussionsupporting

confidence: 79%

“…[38,34] It is known that tachycardia and hypotension is more frequently seen in DSS (Ranjit S et al). [37] Also in our study 5 patients had hypotension and 11 patients had tachycardia, that is more common in DSS/DHF. Thus, although this study provides some evidence that patients with ECG changes were more likely to develop hypotension and tachycardia or bradycardia, it does not provide convincing evidence that cardiac involvement was present.…”

Section: Discussionmentioning

confidence: 86%

“…These arrhythmias are associated to syncope and even sudden death. [35][36][37] In present study, out of 211 dengue patients, abnormal ECG findings were in 57 patients (27.01%), most common ECG finding was sinus bradycardia in 18 patients (31.57%), next was sinus tachycardia in 14 patients (24.56%), and T wave inversion in V1-V4 and V2-V5 was in 4 and 2 patients respectively. ST depression in V1-V4 and V1-V6 was in 6 patients each, generalised T inversion in 6 patients and low voltage in 7 patient, ST-T changes in V2-V5 and V3-V6 both were in 4 patients each, generalised ST elevation in 1 patient and T wave inversion in lead 2, 3 were in 6 patient.…”

Section: Discussionmentioning

confidence: 99%

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Cardiac Manifestation involvement in Dengue Infection

Girdhar¹

2017

jmscr

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Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

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Cardiac Manifestation involvement in Dengue Infection

Girdhar¹

2017

jmscr

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“…Second, only two patients were said to have developed shock, while 17 patients developed hypotension; the definitions of shock or hypotension were not provided. It is known that tachycardia and hypotension is more frequently seen in DSS [42]. Thus, although this study provides some evidence that patients with ECG changes were more likely to develop hypotension and tachycardia or bradycardia, it does not provide convincing evidence that cardiac involvement was present.…”

Section: Clinical and Electrocardiographic Abnormalitiescontrasting

confidence: 47%

Cardiac involvement in dengue infection

Shivanthan

Navinan

Constantine

et al. 2015

J Infect Dev Ctries

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Introduction: Dengue is endemic in the tropics, and complications involving organ systems are seen with varying incidence. Methodology: We performed a systematic review. MEDLINE, EMBASE, Scopus SciVerse, Google Scholar, and LILACS were searched for papers providing information on cardiac involvement in dengue. Results: Cardiac involvement is not uncommon in dengue infection and is often transient, but may be associated with significant morbidity and even mortality. Direct viral invasion, immune mechanisms, electrolyte imbalance, derangement of intracellular calcium ion storage, lactic acidosis, and ischemia due to hypotension all play a role in myocardial dysfunction. The manifestations of cardiac involvement include clinical, electrocardiographic, echocardiographic, cardiac enzyme, and histopathologic abnormalities. Echocardiography appears to be a useful tool for detecting myocardial involvement and should be performed in patients with electrocardiographic abnormalities or hemodynamic instability. Treatment is largely supportive, though there are some anecdotal reports of improvements with specific agents. Conclusions: Knowledge on cardiac manifestations in dengue is limited, and further studies are needed to establish the exact pathophysiology and role of specific agents in the prevention and treatment of cardiac complications in dengue.

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“…In terms of clinical features septic shock and dengue shock clearly have some overlap although there may be some distinguishing features [79].…”

Section: Fluid Resuscitationmentioning

confidence: 99%

What’s New in the Recognition and Management of Septic Shock in Children: Dos and Don'ts

Argent

2013

Curr Pediatr Rep

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While there has been a reduction in the number of children dying of septic shock in the richer countries of the world, septic shock remains an important cause of both mortality and morbidity for children across the world. Major reduction in the incidence of septic shock will depend on the implementation of public health measures, including immunization. Improvements in outcome of pediatric septic shock have been closely linked to early recognition (although this may be challenging in many situations); early antibiotic administration; early and appropriate fluid administration and subsequent escalation of critical care. A particular challenge has been the development and implementation of systems to ensure that these elements of management are reliably and efficiently implemented in children (even in well-resourced countries). Recent studies have highlighted the complexity of caring for patients with acute severe sepsis and septic shock in countries with fewer resources, and there is an urgent need for further studies to elucidate the implications of these studies for the management of children with septic shock, particularly in settings where additional critical care support such as inotropic or ventilator support may not be readily available.

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Early Differentiation Between Dengue and Septic Shock by Comparison of Admission Hemodynamic, Clinical, and Laboratory Variables

Cited by 23 publications

References 29 publications

Cardiac Manifestation involvement in Dengue Infection

Cardiac Manifestation involvement in Dengue Infection

Cardiac involvement in dengue infection

What’s New in the Recognition and Management of Septic Shock in Children: Dos and Don'ts

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