Early estimates of the incidence trend and the reproductive number of the monkeypox epidemic in Brazil

Schrarstzhaupt, Isaac N.; Fontes-Dutra, Mellanie; Díaz-Quijano, Fredi Alexander

doi:10.1016/j.tmaid.2022.102484

Cited by 9 publications

(7 citation statements)

References 31 publications

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“…Moreover, the effective public health measure adoption in these endemic regions has also limited the spread of mpox infections [ 4 , 7 ]. An additional factor that should be noted is that mpox has neither a lifelong survival nature nor has purely the characteristic nature of sexually transmitted diseases such as HIV [ 4 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. The disease mostly remains self-limiting and resolves within 2–4 weeks of symptoms, as the host slowly develops immunity against it.…”

Section: Resultsmentioning

confidence: 99%

“…So far, these are limited to African countries; however, some recent outbreaks have been reported in other continents as far as America, Asia, and Europe. The situation is thus alarming for scientific and healthcare networks around the world [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ].…”

Section: Introductionmentioning

confidence: 99%

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Recent Developments in Mpox Prevention and Treatment Options

Malik¹,

Ahmad

Ahsan

et al. 2023

Vaccines

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Human mpox is an emerging epidemic in the world. The monkey pox virus (MPXV) belongs to the same family of zoonotic Orthopoxviridae as that of the smallpox virus and exhibits similar clinical symptomology. Information regarding its diagnostics, disease epidemiology, surveillance, preventive methods, and treatment strategies are being collated with time. The purpose of this review is to trace the recent events in the scientific platform that have defined new preventive and treatment strategies against mpox. A methodological approach has been used to gather data from the latest literature to comprehensively overview the emerging treatment options. The results portion will cover details regarding the prevention of mpox. It will also shed light on a brief description of contemporary vaccines and antiviral agents that have been evaluated for their treatment potential since the emergence of the mpox threat. These treatment options are setting the pace for controlling the widespread monkeypox infection. However, the limitations attached to these treatment strategies need to be tackled quickly to increase their efficacy so that they can be deployed on a large scale for the prevention of this epidemic becoming another pandemic in this decade.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Recent Developments in Mpox Prevention and Treatment Options

Malik¹,

Ahmad

Ahsan

et al. 2023

Vaccines

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“…Similarly, some other cases have been reported in the UK, back in April 2022 [ 38 ]. According to WHO, approximately 110 countries have already reported confirmed cases of Mpox, including UK, Spain, Portugal, Canada, Germany, Belgium, Italy, France, Netherlands, Sweden, UAE, Czech Republic, Brazil, America, and DRC [ 4 , 5 , 16 , 21 , 24 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ].…”

Section: Introductionmentioning

confidence: 99%

Mitigation Measures to Control the Expected Mpox Outbreak in a Developing Country—Pakistani Scenario

Malik¹,

Asghar

Waheed

2023

Vaccines

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Mpox (previously named Monkeypox) is one of the neglected viral infectious diseases that remained silent for a long period before finally emerging as a threat to the healthcare system in endemic regions of the world in recent years. It has been mostly centered in African countries but has now been reported in other non-endemic regions as well. While keeping a strict eye on COVID pandemic handling, there is a need to remain concerned and alert about viral threats such as Mpox infections in the future. This situation has altered the healthcare system of endemic regions, including Pakistan, to stay vigilant against the expected Mpox outbreaks in the coming months. Though no specific cases have been reported in Pakistan, the healthcare system needs to take mitigation measures to tackle an expected threat before it arrives. This is important in order to avoid another major shock to the health care system of Pakistan. Moreover, since no specific treatment is available for Mpox, we can only rely upon mitigation measures, involving preventive and treatment strategies devised around some already in-use antiviral agents against Mpox viruses. Moreover, there is an imperative need to proactively prepare the healthcare system against Mpox outbreaks, spread awareness, and involve the public in a participatory approach to stay well prepared against any such infection. Moreover, there is a need to utilize financial sources, aids, and funds wisely, to create awareness in the public about such expected healthcare outbreaks in the future.

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“…The epidemic curve followed similar trends in these countries, peaking in the first week of July and starting to decrease during the second half of the month [5]. The basic reproduction number R 0 of the disease has been computed for some European countries [6][7][8], and estimates on the effective reproduction number and instantaneous growth rate are available as well for some countries [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Estimates of mpox effective reproduction number in Spain, April–August 2022

García-García¹,

Gómez‐Barroso²,

Hernando³

et al. 2023

Epidemiol. Infect.

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We analysed the transmission of the human mpox virus in Spain by estimating the effective reproduction number of the disease from official surveillance data. Our computations show that this decreased steadily after an initial burst phase, dropping below 1 on July 12, and thus the outbreak was expected to reduce in the following weeks. Differences in trends were found across geographical regions of the country and across MSM and heterosexual populations.

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Early estimates of the incidence trend and the reproductive number of the monkeypox epidemic in Brazil

Cited by 9 publications

References 31 publications

Recent Developments in Mpox Prevention and Treatment Options

Recent Developments in Mpox Prevention and Treatment Options

Mitigation Measures to Control the Expected Mpox Outbreak in a Developing Country—Pakistani Scenario

Estimates of mpox effective reproduction number in Spain, April–August 2022

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