“…Large and ptotic breasts have usually a wide base and, consequently, implants are keener to lateral and superior movements. In subpectoral reconstruction the muscle itself prevents the implant to move in a superior direction, while the use of a serratus fascia flap [ 26 ], meshes [ 27 , 28 ] or the ‘dermal cage’ technique [ 29 ] have been described to avoid later displacement. In pre-pectoral reconstruction, instead, ADMs or non-biological mesh are needed to fix the implant to the chest wall in a proper position [ 14 , 15 ]; nevertheless, these products do not come without complication and adjunctive cost to the procedure [ 17–20 ].…”