“…Though cardiac catheterization and angiocardiography may be helpful and yield valuable information, in many patients no intracardiac investigations have been carried out because of repeated warnings about the dangers of these procedures in such patients (Baker, Brinton, and Channell, 1950;Engle et al, 1950;Schaede, 1951;Blacket et al, 1952;Campbell, 1953;Kjellberg et al, 1955;Brown, Heath, and Whitaker, 1956;Wood, 1956;Mayer, Nadas, and Ongley, 1957); in addition there is a lack of detailed knowledge about the haemodynamic effects peculiar to this lesion. While there is no doubt that catheterization carries a greater risk in these circumstances, increased experience of investigative techniques in general, plus improved methods of dealing with rapid paroxysmal tachycardia and cardiac arrest, have made it much less hazardous than it used to be.…”