Eccrine syringofibroadenoma radiation treatment of an unusual presentation

Abstract

Benign skin diseases have seldom been treated with radiotherapy, unless resistant to other treatments. Eccrine syringofibroadenoma (ESFA) is a rare benign eccrine tumor. ESFA very rarely presents bilateral lesions, and seldom a nonsurgical treatment has been proposed. An exceptional case of bilateral ESFA of the foot is presented; radiotherapy was effective in treating both lesions with good cosmetic results.

Solitary eccrine syringofibroadenoma - Case Report

“…Other rarely reported treatments are: cryotherapy, curettage, electrodessication, laser and radiotherapy, with variable patient outcomes. 7 In the case reported here, we opted for a reconstruction by a reverseflow supramalleolar flap because the tumor was bulky and located in an extremity, which makes the reconstruction of the surgical defect difficult, due to poor skin mobility. Furthermore, the use of the flap promotes better coverage of the area and provides a better protection to the bone surface, given that the lateral malleolus is an area that is highly exposed to trauma.…”

Palmar syringofibroadenoma-like lesions in Clouston syndrome treated with CO2 ablative laser

“…However, some treatments have been tried in other types of ESFA with variable degrees of success, namely surgical excision (if solitary lesion), cryotherapy, radiotherapy, photodynamic therapy, or systemic retinoids. 7 , 8 , 9 Although there are a few reports of ESFA successfully treated with CO 2 ablative laser, 5 to our knowledge, there is no published case of CO 2 ablative laser treatment in an ESFA associated with Clouston syndrome. Our patient was treated with CO 2 ablative laser, which led to regained functionality of her treated hand and satisfying esthetic results without complications.…”

Recalcitrant erosive plaques on the palms and soles: A rare manifestation of eccrine syringofibroadenoma

“…ESFA may resolve spontaneously; however, alternative treatments for refractory ESFA have been reported with varying degrees of success, including radiotherapy, photodynamic therapy, 5-fluorouracil, and imiquimod. 9 , 10 …”

“…ESFA may resolve spontaneously; however, alternative treatments for refractory ESFA have been reported with varying degrees of success, including radiotherapy, photodynamic therapy, 5-fluorouracil, and imiquimod. 9,10 For our patient, after the diagnosis of ESFA was made, we continued halobetasol ointment 0.05% for 1 month with minor improvement. Because of the patient's concerns regarding the cost of the medication, we replaced halobetasol with triamcinolone ointment 0.1% twice daily, with home wound care 3 times a week using petrolatum gauze and fabric gauze bandages.…”