“…50 Ten studies were RCTs, 20 , 21 , 25 , 26 , 34 , 40–43 , 48 3 were controlled clinical trials, 27 , 29 , 35 3 were cohort analytic studies with >1 group (2 or 3 groups, before and after), 32 , 39 , 46 and 13 were cohort analytic studies with a single group (before and after). 22–24 , 28 , 33 , 36–38 , 44 , 45 , 47 , 49 , 50…”