Efek Analgetik dan Antiinflamasi Kaempferia Galanga (Kencur)

Cahyawati, Putu Nita

doi:10.22225/wicaksana.4.1.1811.15-19

Cited by 7 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Wedang Jahe has used traditionally to keep body warm, increase appetite, improve digestion system, and help relieve rheumatic pain [21]. Ethyl-p-methoxycinnamate has protective effect since savage ROS and inhibits IL-1, and TNF-alpha [24] -oryzanol as anti-inflammatory prevent IL-6, TNF-α, and NF-κB [23].…”

Section: Resultsmentioning

confidence: 99%

Study of Jamu as Indonesian Herbal Medicine for Covid-19 Treatment

Gondokesumo¹,

Budipramana²,

Aini³

2021

Advances in Health Sciences Research

View full text Add to dashboard Cite

The spread of the Severe Acute Respiratory Syndrome (SARS-CoV-2) virus has caused the COVID-19 pandemic for more than a year. Daily cases in Indonesia keep increasing following the high mortality rate, entitling it as the epicentre country of Asia. The government advises patients with mild symptoms to take self-isolation at home. Due to its rich cultures and beliefs in Indonesia, patients on independent isolation tend to take treatment on their own accord, such as using traditional herbal medicine renowned as jamu. This article is aimed to review the use of various types of concoctions in jamu taken as the prevention and additional therapy for COVID-19 patients. The review may advantage for COVID-19 treatment discovery through indigenous compound and medical care in societies. In writing this article, the author collected information from related articles in online sources such as Google Scholar, Pubmed, Science Direct, as well as circulars from the Indonesian Ministry of Health and treatment guidelines from the Food and Drug Supervisory Agency. Polyherbal formulations that have been widely recommended for COVID-19 treatment are 9 jamu formulas within Zingiber officiale for the highest herbal compound used and followed by other 21 herbal plants such as Curcuma zanthorrhiza, Cinnomomun verum, Citrus aurantifolia fruit, Cymbapogon sitratus, Curcuma longa, Alpinea galangal, etc. Five of all founded jamu identified for antivirus agent as well as mostly applied in immune booster tradisionally. Moreover, all of jamu formulas has antioxidant activities and antiinflamatory effect that would be promising for COVID-19 treatment, especially for Jamu Pahitan and Wedang Secang could be the candidates for COVID-19 therapy through increasing immunity and reducing risk factors for each symptom. No antagonistic interactions were found in the herbal concoctions, while several synergistic interactions that increase the pharmacological activity. This study would contribute a remarkable literacy since the use of jamu in preventing and treating COVID-19 as a new disease requires careful consideration due to the limited scientific data and clinical evidence to support its use.

show abstract

Section: Resultsmentioning

confidence: 99%

Study of Jamu as Indonesian Herbal Medicine for Covid-19 Treatment

Gondokesumo¹,

Budipramana²,

Aini³

2021

Advances in Health Sciences Research

View full text Add to dashboard Cite

show abstract

“…The boreh preparation was formulated and developed into an innovative peel-off product, namely UNO, by the executive team containing TOGA-based natural ingredients, such as ginger, turmeric, and galangal (Ariani et al, 2020;Isna et al, 2020). These materials were reported to have empirical effects on reducing pain (Akbar et al, 2021;Cahyawati, 2020;Fahryl & Carolia, 2019). Product characteristics were evaluated in the School of Pharmacy Mahaganesha Laboratory before being demonstrated to the target community of the empowerment program.…”

Section: Methodsmentioning

confidence: 99%

Empowerment Program in Pesagi Village Community: Assistance in Compounding Innovative Peel-off Pain Reliever (UNO) Derived from Family Medicinal Plants

Kurnianta¹,

Yuliawati²,

Musthika³

et al. 2022

Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Comm

View full text Add to dashboard Cite

The abundance of family medicinal plants (TOGA) growing in the yards of the house can be utilized for one of the health products called boreh, a traditional medicine used from generation to generation by the Balinese. Boreh can be innovated into a peel-oﬀ preparation form that has some potential to increase public interest in traditional medicine. The contents of TOGA, such as ginger, turmeric, and galangal in the peel-oﬀ boreh preparation, may exhibit beneﬁcial eﬀects as a pain reliever. Therefore, the mentioned product can be used to overcome pain problems that are commonly found in the people of Pesagi Village. The ideas related to compounding certain innovative herbal preparations for overcoming health problems in Pesagi Village were carried out through community empowerment activities. A series of program activities took place during January-April 2022. The purpose of this community empowerment program was to provide training and assistance activities to the people of Pesagi Village in the practice of utilizing TOGA as an innovative boreh peel-oﬀ preparation, namely UNO, with empirical pain reliever properties. Guidance and assistance in compounding practice were based on the results of dosage formulation previously developed by the executive team in the School of Pharmacy Mahaganesha Laboratory. This empowerment program was executed through a learning-by-doing approach, integrated training, participatory practice, and guided mentoring by the executive team with knowledge and skills evaluation (pre-test and post-test, p=0.000, 95%). After the empowerment program, the community has been able to practice how to turn TOGA from the ground into a useful product. The innovative products in this empowerment program may oﬀer some potential beneﬁts to overcome certain health-related problems of the community in Pesagi Village, such as joint pain. The success of this program may encourage the sustainability of the program in the future.

show abstract

“…Cyanide can bind and de-activate several enzymes, especially those containing iron and cobalt. As a result, structural integrity and enzyme effectiveness are lost (Cahyawati, 2017).…”

Section: Cyanide Acidmentioning

confidence: 99%

“…Cytochrome oxidase a3 plays an essential role in reducing oxygen to water through the phosphorylation oxidation process. The bond between cyanide and ferric (Fe 3+ ) in cytochrome oxidase a3 results can inhibit terminal enzymes in the respiratory chain, electron transport chain, and phosphorylation oxidation process (Cahyawati, 2017).…”

Section: Cyanide Acidmentioning

confidence: 99%

See 1 more Smart Citation

The Potential Use of Anti-Nutritional Compounds of Gadung Tubers as Biopesticides

et al. 2021

View full text Add to dashboard Cite

The use of gadung (Discorea hispida dennst.) tubers as food source is not seen as an attractive option due to dioscorine and cyanide anti-nutritional compounds contained therein. The presence of dioscorine and cyanide compounds makes gadung tubers known as poisonous food. Although the community has known its poisonous nature, the use of gadung tubers as natural pesticides (biopesticides) is not commonly known by the community. Using gadung tubers as biopesticides provides solution to unanswered problems caused by chemical pesticides. This article seeks to describe the potential use of anti-nutritional compounds of gadung tubers as biopesticides based on literature reviews. Various literature related to anti-nutritional compounds contained in gadung tubers and their use as biopesticides have been analyzed in depth. The literature review results show that dioscorine and cyanide anti-nutritional compounds are toxic and can be used as biopesticides. The effectiveness of gadung tubers on various agricultural pests depends entirely on the concentration of gadung tubers used. The use of gadung tubers as biopesticides is needed to increase and maintain the productivity of agricultural land in addition to preserving natural resources.

show abstract

Efek Analgetik dan Antiinflamasi Kaempferia Galanga (Kencur)

Cited by 7 publications

References 0 publications

Study of Jamu as Indonesian Herbal Medicine for Covid-19 Treatment

Study of Jamu as Indonesian Herbal Medicine for Covid-19 Treatment

Empowerment Program in Pesagi Village Community: Assistance in Compounding Innovative Peel-off Pain Reliever (UNO) Derived from Family Medicinal Plants

The Potential Use of Anti-Nutritional Compounds of Gadung Tubers as Biopesticides

Contact Info

Product

Resources

About