2022
DOI: 10.20884/1.mandala.2022.15.1.5784
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EFEK PEMBERIAN EKSTRAK ETANOL SELEDRI (Apium graveolens L.) TERHADAP KADAR ASAM URAT PADA TIKUS PUTIH (Sprague dawley) MODEL CHRONIC KIDNEY DISEASE

Abstract: Chronic kidney disease (CKD) masih menjadi masalah kesehatan masyarakat di seluruh dunia. CKD terjadi akibat pengurangan nefron fungsional dan penurunan laju filtrasi glomerulus (GFR) sehingga terjadi penurunan fungsi ginjal yang akan menyebabkan gangguan dalam proses fisiologik ginjal, terutama dalam hal ekskresi zat-zat sisa termasuk asam urat. Laju filtrasi glomerulus ≤50% mulai terjadi peningkatan kadar kreatinin, urea, dan juga asam urat. Peningkatan asam urat akan terus bertambah seiring dengan penurunan… Show more

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“…Celery leaves have been traditionally used for various purposes such as rheumatism, dry eyes, hypertension, cough, reducing cholesterol levels, and promoting hair growth 14 , as well as for their antibacterial, antispasmodic, uric acid-reducing, antirheumatic, sedative, and antihypertensive properties. 15 Celery contains flavonoids that can act as potential anti-allergic, anti-inflammatory, antiviral, anticarcinogenic, and antioxidant agents. 16 It also contains saponins, tannins, essential oil, apigenin, vitamins A, B, and C 15,17 , iron, calcium, sulfur, and phosphorus 18 .…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Celery leaves have been traditionally used for various purposes such as rheumatism, dry eyes, hypertension, cough, reducing cholesterol levels, and promoting hair growth 14 , as well as for their antibacterial, antispasmodic, uric acid-reducing, antirheumatic, sedative, and antihypertensive properties. 15 Celery contains flavonoids that can act as potential anti-allergic, anti-inflammatory, antiviral, anticarcinogenic, and antioxidant agents. 16 It also contains saponins, tannins, essential oil, apigenin, vitamins A, B, and C 15,17 , iron, calcium, sulfur, and phosphorus 18 .…”
Section: Introductionmentioning
confidence: 99%
“…15 Celery contains flavonoids that can act as potential anti-allergic, anti-inflammatory, antiviral, anticarcinogenic, and antioxidant agents. 16 It also contains saponins, tannins, essential oil, apigenin, vitamins A, B, and C 15,17 , iron, calcium, sulfur, and phosphorus 18 . All contents are present in each section of the gel; therefore, each section can be used independently.…”
Section: Introductionmentioning
confidence: 99%