EFEKTIVITAS ANTIJAMUR KOMBINASI KETOKONAZOL DENGAN MINYAK ATSIRI SEREH WANGI  (Cymbopogon nardus (L.) Rendle)

Lely, Nilda; Pratiwi, Reni; Imanda, Yunita Listiani Imanda Listiani

doi:10.24198/ijas.v7i2.13793

Cited by 9 publications

(12 citation statements)

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“…Ketoconazole was the first oral azole to be used clinically. Azole itself is a synthetic compound that is classified into imidazole or triazole (Lely et al, 2017).…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial Test of Telang Flower Extract (Clitoria ternatea L.) against the Growth of Candida albicans

Wijaya¹,

Destiawan²,

Cahyariza³

2023

J. Prisma. Sains

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Candidiasis is an acute and subacute fungal infection caused by the Candida group, especially Candida albicans. Infectious diseases due to microbes can be treated using modern drugs, namely antifungals. In some cases, antimicrobials often develop resistance due to improper administration. The occurrence of such resistance encourages further research on new active ingredients that can be used as antimicrobial alternatives, especially from plant sources containing flavonoids. The purpose of this study is to determine the effect of antimicrobial content of ethanol extract 70% of Telang flowers on the growth of C. albicans. This research is a laboratory experimental research with post test control group design only method. Determination of antimicrobial activity is carried out by the pitting method. Telang flower extract that has been diluted with 10% DMSO, taken as much as 30µl then dripped into the well. Positive control using antimicrobial ketocenazole and negative control using DMSO 10% which was dripped on the well as much as 30µl. Based on the results of observations, the inhibition zone is only formed in positive control with an average of 15.5 + 0.4 mm. The results of ethanol extract of 70% Telang flowers that have been conducted did not show antimicrobial activity against fungal growth C. albicans. The absence of this inhibitory zone is due to the unknown concentration of active compounds of Telang flowers that are responsible as antimicrobials, so it is necessary to conduct research on the search for concentrations of active compounds that have the ability as antimicrobials.

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“…Ketoconazole was the first oral azole to be used clinically. Azole itself is a synthetic compound that is classified into imidazole or triazole (Lely et al, 2017).…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial Test of Telang Flower Extract (Clitoria ternatea L.) against the Growth of Candida albicans

Wijaya¹,

Destiawan²,

Cahyariza³

2023

J. Prisma. Sains

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“…Media tumbuh PDA dan PDB yang telah disiapkan ditambahkan larutan minyak atsiri. Volume PDA cair yang pada setiap cawan petri sebanyak 9,9 ml dengan larutan konsentrasinya sebanyak 0,1 ml sehingga total volumenya menjadi 10 ml (Lely et al 2017). Volume PDB yang digunakan pada setiap botol jar yakni 29,7 ml dengan larutan konsentrasinya sebesar 0,3 ml.…”

Section: Pembuatan Media Tumbuh Isolatunclassified

Uji Penghambatan Minyak Atsiri Kayu Putih dan Kunyit terhadap Patogen Penyebab Penyakit pada Tanaman Murbei Secara In Vitro

Firmansyah¹,

Yuwono

2022

J-Silvtrop

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Mulberry plants (Morus sp.) are one of the non-timber forest products that are used as feedfor silkworms, foodstuffs, or medicines. Plants that are attacked by disease can certainly harmvarious aspects, one of which can reduce the quality and quantity of plants. Vegetable pesticidescan be a solution to prevent the spread of the disease. This study aims to determine the symptomsof diseases that appear in mulberry plants and their spread in mahogany and find out theinhibitory power and concentration of essential oils that work optimally. Observations weremade using eucalyptus essential oil, turmeric essential oil, and a combination of both withconcentrations of 1%, 3%, and 5% on PDA media and GDP media. Based on observations, thetype of fungus found is Rhizoctonia sp.. The results of the observations showed that the optimalessential oil as an inhibitor of pathogenic growth is turmeric essential oil with a concentration of3% and a combined essential oil concentration of 5%. The results of the inoculation showed thatthere was fungal growth activity on mahogany seedlings so that the fungus could attack otherplants such as forestry plants.

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“…Selain mudah untuk dibudidayakan bahan alam ini memiliki kadungan sitronela dan geraniol yang memiliki sifat antibakteri dan antijamur. [15][16] Berdasarkan penelitian yang telah dilakukan oleh Lely et al (2017) sereh wangi (Cymbopogon nardus) memiliki rata-rata diameter hambat 19,4 ± 15 mm terhadap Candida albicans. 16 Namun, pada penelitian terdahulu masih belum dilakukan penelitian terhadap lama perendaman yang efektif terhadap pertumbuhan Candida albicans.…”

Section: Latar Belakangunclassified

“…[15][16] Berdasarkan penelitian yang telah dilakukan oleh Lely et al (2017) sereh wangi (Cymbopogon nardus) memiliki rata-rata diameter hambat 19,4 ± 15 mm terhadap Candida albicans. 16 Namun, pada penelitian terdahulu masih belum dilakukan penelitian terhadap lama perendaman yang efektif terhadap pertumbuhan Candida albicans. Hal ini yang menarik perhatian penulis untuk melakukan penelitian mengenai lama durasi perendaman plat resin akrilik dalam ekstrak sereh wangi (Cymbopogon nardus) terhadap pertumbuhan Candida albicans.…”

Section: Latar Belakangunclassified

Pengaruh lama perendaman plat resin akrilik dalam ekstrak sereh wangi (cymbopogon nardus)

Siyulan

Yuliarsi

2022

JKGT

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Background: Patients who have lost their teeth can use dentures as an alternative treatment. The use of dentures must also be followed by adequate cleaning. One of several alternative to clean dentures is to use citronella grass (Cymbopogon nardus) which contains active compounds that can reduce the growth of Candida albicans. Objective: To determine the effect of immersion duration of acrylic resin plate in citronella grass on the growth of Candida albicans. Method: The method of this study was experimental laboratory research using 27 samples of acrylic resin plates which were divided into 3 negative control groups, 3 positive control groups and 3 groups using cintronella grass extract with a concentration of 50% with an immersion time of 4 hours, 6 hours and 8 hours. Results: the group with immersion time of 4 hours, 6 hours and 8 hours showed a significant difference to the negative control group, as well as a non-significant difference to the positive control group. Conclusion: The citronella extract group with a concentraition of 50% had a significant effectiveness against the negative control group and the same effectiveness against the positive control group.

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EFEKTIVITAS ANTIJAMUR KOMBINASI KETOKONAZOL DENGAN MINYAK ATSIRI SEREH WANGI (Cymbopogon nardus (L.) Rendle)

Cited by 9 publications

References 0 publications

Antimicrobial Test of Telang Flower Extract (Clitoria ternatea L.) against the Growth of Candida albicans

Antimicrobial Test of Telang Flower Extract (Clitoria ternatea L.) against the Growth of Candida albicans

Uji Penghambatan Minyak Atsiri Kayu Putih dan Kunyit terhadap Patogen Penyebab Penyakit pada Tanaman Murbei Secara In Vitro

Pengaruh lama perendaman plat resin akrilik dalam ekstrak sereh wangi (cymbopogon nardus)

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