Effect of a water-rich diet on adrenal zona glomerulosa in Gerbillus tarabuli

Saadi, Leila; Lebaili, Nemcha

doi:10.1016/j.crvi.2011.12.002

Cited by 8 publications

(12 citation statements)

References 42 publications

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“…It has as main characteristic, the presence of cells arranged in oval groups very attached and with reduced intracellular spaces, similarly to rats (CHANG et al, 2011), Galea spixii (SANTOS et al, 2016) and Gerbilus tarabuli (SAADI;LEBAILI, 2012); the second layer is the fasciculata, characterized by columns of vacuolated cells as in rats (CHANG et al, 2011. ) and Galea spixii (SANTOS et al, 2016.…”

Section: Discussionmentioning

confidence: 98%

Morphology of the adrenal glands of giant anteater (Myrmecophaga tridactyla, Linnaeus, 1758) of wild life

et al. 2016

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ABSTRACT:The Myrmecophaga tridactyla (family Pilosa), popularly known in Brazil as the giant anteater is classified as an endangered species by the main survey agencies of biodiversity preservation around the world. The adrenal glands are important organs, which are related to homeostasis of the animal. This study aimed to describe the morphology of the adrenal glands of M. tridactyla, providing data for future studies related to the production of steroid hormones in specimens exposed to different stress factors. The adrenal glands of 14 specimens were used. The glands were measured, photodocumented and described by light microscopy. The adrenals were positioned in the cranial extremity of the kidneys (left and right) and related medially to the caudal vena cava. The right adrenal gland had an elongated shape while the left adrenal gland had pyramidal or triangular shape. The weight was 4.765±0.129g for the right adrenal and 3.975±0.213g for the left adrenal. The length was 4.50±0.14cm for the right adrenal and 4.28±0.11cm for the left adrenal. The width was 2.60±0.13cm for the right adrenal and 2.37±0.12cm for the left adrenal. The thickness was 0.45±0.11cm for the right adrenal and 0.68±0.14cm for the left adrenal. Statistical differences (p<0.05) between right and left adrenals for all values analyzed were observed. Microscopically it was observed a capsule composed by modeled dense connective tissue lining the organ. Below this capsule, from the outermost to the innermost layer, it was observed a cortical region divided into glomerular, fasciculata and reticular zones with a medullar region occupying the center of the organ. Further studies related to steroidogenesis with specimens collected at different periods of the year are necessary, aiming to observe if there are morphological or hormonal variations in the adrenal glands due to seasonal periods. This information would be of great importance because it could reflect the behavioral habits of this species.

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Section: Discussionmentioning

confidence: 98%

Morphology of the adrenal glands of giant anteater (Myrmecophaga tridactyla, Linnaeus, 1758) of wild life

et al. 2016

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“…In the case of the cortex´s tissue differentiation, it may be suggested that the cells of the same cortical zone may produce different classes of hormones during pregnancy. Saadi and Lebaili [23] suggest that changes in the cortex reflect the anatomical and physiological adaptive capacity of the adrenal gland to stress factors, by changing demand of several adrenal hormones. Glucocorticoids are classified as mediators within the process of the onset of birth and thus required during intrauterine development [9] .…”

Section: Discussionmentioning

confidence: 99%

Development of Adrenal Glands from the Embryonic Phase to Puberty in Spix’s Yellow-toothed Cavies (Galea spixii, Wagler, 1831)

Lobo

Santos

Oliveira

et al. 2018

Braz. arch. biol. technol.

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Several authors have underscored the importance of establishing parameters in morphological development by gender comparison to establish clinical and pre-clinical assays through the use of experimental models. Current research compares the morphometry of right and left adrenal glands of males and females and describes differentiation of the cortex and medulla tissue during the embryonic, pre-puberty and puberty phases in Spix´s yellow-toothed cavies. Embryos aged 22 (22D), 25 (25D), 30 (30D), 40 (44D) and >50 (50D) days of gestation and neonates aged 15 (15DPN) (DPN= Days postnatal), 30 (30DPN) and 90 (90DPN) days after birth were analyzed. Comparisons included morphometric and histological analysis in all periods described. When compared the right and left adrenal glands, results show that the length and width have statistical differences (p<0.05). Statistical difference between right and left glans for weight occurred only after 30D in males and after 50D in females. When compared male and females, no statistical difference in the right and left glands was extant. In the case of tissue differences, the glomerular zone is the first to emerge after 22D, followed by the fasciculate zone after 25D and by the reticular zone during the post-natal period. Medullar tissue was spread between the cortical tissue at the onset of development, establishing itself at the center of the organ since the end of pregnancy (>50D) up to puberty. Considering tissue differentiation, there was no difference between the adrenal glands of male and female cavies or between the right and left adrenal glands.

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“…Regarding the different zones of the adrenal cortex in SYT cavies: the glomerular zone had presence of groups of ovoid cells, adhered with each other and with reduced intracellular spaces, similar that found in rats (Chang et al, 2011) and Gerbilus tarabuli (Saadi and Lebaili, 2012); the fasciculate zone was characterized by long cords of vacuolated cells, as found in rats (Chang et al, 2011); the reticular zone had in its parenchyma, a plot of irregular cords of cells, anastomosed, and, with random arrangement. Two types of cells were found: one with fine chromatin and visible nucleolus and other type with picnotic nucleus, which is related to cellular apoptosis, similar that found in Lagostamus maximus (Ribes et al, 1999).…”

Section: ) and Myocastor Coypusmentioning

confidence: 93%

“…In Gerbillus tarabili (Saadi and Lebaili, 2012) undergoing diet rich in water, the cells of glomerular zone were arranged in clusters surrounded by a network of fenestrated capillaries with rounded shape and variable size. Their nuclei varied in size and had one nucleolus.…”

Section: ) and Myocastor Coypusmentioning

confidence: 99%

“…In our study, using animals bred in captivity, these characteristics were observed in the cells of the fasciculate zone. Saadi and Lebaili (2012) suggest that changes in the cortex are a reflex of the anatomical and physiological adaptive capacity of the adrenal gland to stress factors. Similar features of the fasciculate zone of SYT cavies were found in Lagostomus maximus (Ribes et al, 1999).…”

Section: ) and Myocastor Coypusmentioning

confidence: 99%

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Adrenal glands of Spix's yellow-toothed cavy (Galea spixii, Wagler, 1831): morphological and morphometric aspects

et al. 2016

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Considering the physiological importance and need of greater morphophysiological knowledge of adrenal glands, the aims of present study were compare the morphometric data between left and right adrenal of male and female; perform a histological, scanning and transmission electron microscopy study showing tissue constitution of glands; finally, in order to define the presence and correct site of the cytochrome P450c17 expression in adrenal glands, immunohistochemical study of this enzyme was performed in 18 adrenal glands (right n=9 and left n=9) of nine adult Galea spixii (four males and five females). Right adrenal was more cranially positioned than left adrenal; dimensions (weight, length and width) of right adrenal was larger than left adrenal; no differences between male and female body and adrenal measurements were found; the morphology of cells and different amounts of lipid droplets may be related to the different demands of steroid hormones production, related to each zone of the adrenal cortex; and, the cytochrome P450c17 immunolocalization in fasciculate and reticular zone may be related with synthesis of 17-hydroxy-pregnenolone, 17-hydroxy-progesterone, dehydroepiandrosterone or androstenedione.Keywords: adrenal cortex, adrenal medulla, CYP, steroidogenic enzymes, wild rodents. Glândulas adrenais de preás (Galea spixii, Wagler, 1831):aspectos morfológicos e morfométricos ResumoConsiderando a importância fisiológica e a necessidade de melhor conhecimento morfofisiológico das glândulas adrenais, os objetivos do presente estudo foram comparar dados morfométricos entre adrenais direitas e esquerdas de machos e fêmeas; realizar estudos histológicos e microscopia eletrônica de varredura e transmissão revelando a constituição tecidual das glândulas; finalmente, foi realizado estudo imunohistoquímico com objetivo de definir a presença e correto sítio de expressão da citocromo P450c17 nas glândulas adrenais em 18 glândulas adrenais (direita n=9 e esquerda n=9) de nove Galea spixii adultos (quatro machos e cinco fêmeas). A glândula adrenal direita estava posicionada mais cranialmente que a adrenal esquerda; as dimensões (peso, comprimento e largura) da glândula adrenal direita foram maiores que as da esquerda; não houve diferença entre as medidas corpóreas e das adrenais entre machos e fêmeas; a morfologia das células e diferentes quantidades de gotículas lipídicas podem estar relacionadas a diferentes demandas na produção de hormônios esteroides relacionados a cada zona do córtex adrenal; e, a imunolocalização da citocromo P450 na zona fasciculada e reticular pode estar relacionado com a síntese de 17-hidroxi-pregnenolona, 17-hidroxi-progesterona, dehidroepiandrosterona ou androstenediona.Palavras-chave: córtex adrenal, medula adrenal, CYP17, enzimas esteroidogênicas, roedores silvestres.

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Effect of a water-rich diet on adrenal zona glomerulosa in Gerbillus tarabuli

Cited by 8 publications

References 42 publications

Morphology of the adrenal glands of giant anteater (Myrmecophaga tridactyla, Linnaeus, 1758) of wild life

Morphology of the adrenal glands of giant anteater (Myrmecophaga tridactyla, Linnaeus, 1758) of wild life

Development of Adrenal Glands from the Embryonic Phase to Puberty in Spix’s Yellow-toothed Cavies (Galea spixii, Wagler, 1831)

Adrenal glands of Spix's yellow-toothed cavy (Galea spixii, Wagler, 1831): morphological and morphometric aspects

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