Effect of acute Cu exposure on immune response mechanisms of golden cuttlefish (Sepia esculenta)

Bao, Xiaokai; Li, Yan; Liu, Xiumei; Feng, Yanwei; Xu, Xiaohui; Sun, Guohua; Li, Bin; Li, Zan; Yang, Jianmin

doi:10.1016/j.fsi.2022.09.021

Cited by 6 publications

(2 citation statements)

References 67 publications

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“…About four weeks later, larvae were hatched and divided into the control group (C) and the Cu-exposed group (Cu). According to the relevant research results from our laboratory on S. esculenta [34,35], 50 µg/L of Cu was produced by dissolution of CuCl 2 × H 2 O 2 powder with 99% AR was used to expose larvae. We collected larvae at 0 h (C_0 h), 4 h (C_4 h and Cu_4 h), and 24 h (C_24 h and Cu_24 h).…”

Section: S Esculenta Larvae and Exposurementioning

confidence: 99%

Preliminary Exploration of Metabolic Mechanisms in Copper-Exposed Sepia esculenta Based on Transcriptome Analysis

Jiang

Xu³

et al. 2023

Metabolites

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As a common and high-concentration heavy metal in the ocean, Cu can induce metal toxicity and significantly affect the metabolic function of marine organisms. Sepia esculenta is an important economic cephalopod found along the east coast of China, the growth, movement, and reproduction of which are all affected by heavy metals. Hitherto, the specific metabolic mechanism of heavy-metal exposure in S. esculenta is still unclear. In this study, we identified 1131 DEGs through transcriptome analysis of larval S. esculenta within 24 h of Cu exposure. GO and KEGG functional enrichment analysis results indicated that Cu exposure may affect purine metabolism, protein digestion and absorption, cholesterol metabolism, and other metabolic processes in S. esculenta larvae. It is worth noting that in this study we explore metabolic mechanism of Cu-exposed S. esculenta larvae through the comprehensive analysis of protein–protein interaction network and KEGG enrichment analysis for the first time and find 20 identified key and hub genes such as CYP7A1, CYP3A11, and ABCA1. Based on their expression, we preliminarily speculate that Cu exposure may inhibit multiple metabolic processes and induce metabolic disorders. Our results lay a foundation for further understanding the metabolic mechanism of S. esculenta against heavy metals and provide theoretical help for S. esculenta artificial breeding.

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Section: S Esculenta Larvae and Exposurementioning

confidence: 99%

Preliminary Exploration of Metabolic Mechanisms in Copper-Exposed Sepia esculenta Based on Transcriptome Analysis

Jiang

Xu³

et al. 2023

Metabolites

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“…Therefore, it is used in different industries from automotive to aerospace [ 72 ] and medicine [ 74 ]. It has been applied for applications, such as catalysis and films [ 75 ], microelectronics and electronics, heating [ 73 ], electrical applications [ 71 , 72 ], marine applications [ 76 ], and medical devices, water and food applications [ 77 ]. Research in the medical field in the literature for the reduction of bacteria populations is wide, from marine organisms [ 78 ] to bees [ 79 ].…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Medical Grade Resin with Enhanced Mechanical and Antibacterial Properties: The Effect of Copper Nano-Inclusions in Vat Polymerization (VPP) Additive Manufacturing

Vidakis

Petousis

Papadakis

et al. 2022

JFB

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Vat photopolymerization (VPP) is an additive manufacturing process commonly used in medical applications. This work aims, for the first time in the literature, to extend and enhance the performance of a commercial medical-grade resin for the VPP process, with the development of nanocomposites, using Copper (Cu) nanoparticles as the additive at two different concentrations. The addition of the Cu nanoparticles was expected to enhance the mechanical properties of the resin and to enable biocidal properties on the nanocomposites since Cu is known for its antibacterial performance. The effect of the Cu concentration was investigated. The nanocomposites were prepared with high-shear stirring. Specimens were 3D printed following international standards for mechanical testing. Their thermal and spectroscopic response was also investigated. The morphological characteristics were examined. The antibacterial performance was evaluated with an agar well diffusion screening process. The experimental results were analyzed with statistical modeling tools with two control parameters (three levels each) and eleven response parameters. Cu enhanced the mechanical properties in all cases studied. 0.5 wt.% Cu nanocomposite showed the highest improvement (approximately 11% in tensile and 10% in flexural strength). The antibacterial performance was sufficient against S. aureus and marginal against E. coli.

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Transcriptome analysis reveals the immune response mechanism of golden cuttlefish (Sepia esculenta) larvae exposed to ink

Chang,

Zhao,

Ren

et al. 2024

Comparative Biochemistry and Physiology Part D: Genomics and Pr

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Effect of acute Cu exposure on immune response mechanisms of golden cuttlefish (Sepia esculenta)

Cited by 6 publications

References 67 publications

Preliminary Exploration of Metabolic Mechanisms in Copper-Exposed Sepia esculenta Based on Transcriptome Analysis

Preliminary Exploration of Metabolic Mechanisms in Copper-Exposed Sepia esculenta Based on Transcriptome Analysis

Multifunctional Medical Grade Resin with Enhanced Mechanical and Antibacterial Properties: The Effect of Copper Nano-Inclusions in Vat Polymerization (VPP) Additive Manufacturing

Transcriptome analysis reveals the immune response mechanism of golden cuttlefish (Sepia esculenta) larvae exposed to ink

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