Effect of Age at Menopause on Blood Pressure in Postmenopausal Women

Izumi, Yasukatsu; Matsumoto, Kenji; Ozawa, Yukio; Kasamaki, Yuji; SHINNDO, A; Ohta, Masakatsu; Jumabay, Medet; Nakayama, Tomohiro; Yokoyama, Eise; Shimabukuro, Hiroyuki

doi:10.1016/j.amjhyper.2007.04.019

Cited by 69 publications

(55 citation statements)

References 22 publications

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“…Bagi wanita usia menopause diharapkan dapat menyadari pentingnya kesehatan dengan menerapkan pola hidup sehat dan tetap melakukan pengukuran tekanan darah secara rutin. Izumi et al (2007), melakukan survei medis di barat laut Cina, terhadap 150 perempuan pascamenopause, dan korelasi positif ditemukan antara periode pascamenopause baik tekanan darah sistolik maupun tekanan darah diastolik. Tekanan darah, usia saat menopause, dan periode pascamenopause yang tidak signifikan berhubungan dengan indeks massa tubuh, aktivitas renin plasma, laju filtrasi glomerulus, atau nilainilai ekskresi natrium dan kalium.…”

Section: Pendahuluanunclassified

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Korelasi Asupan Makanan, Stres, Dan Aktivitas Fisik Dengan Hipertensi Pada Usia Menopause

Yulistina

Deliana

Rustiana

2017

UJPH

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AbstrakPeningkatan tekanan darah pada wanita usia menopause menunjukkan bahwa defisiensi estrogen mungkin menjadi kontributor untuk tekanan darah tinggi pada wanita lanjut usia sebesar 65 % sedangkan 35 % dapat dipengaruhi oleh faktor gaya hidup dan faktor lainnya. Penelitian ini bertujuan untuk menganalisis faktor gaya hidup terhadap hipertensi pada usia menopause di Puskesmas Tlogosari Wetan Semarang. Jenis penelitian ini kuantitatif dengan menggunakan desain cross sectional. Sampel pada penelitian sebanyak 50 orang. Pengukuran variabel-variabelnya menggunakan data primer dan sekunder. Analisis data menggunakan analisis univariat, bivariat uji Spearman rank, dan multivariat uji Regresi Logistik. Hasil penelitian menunjukkan ada hubungan yang bermakna antara aktivitas fisik, stres, asupan lemak, asupan natrium (p<0,05) terhadap hipertensi pada usia menopause. Hasil regresi logistik menunjukkan asupan natrium memiliki tingkat risiko lebih tinggi terhadap hipertensi (p=0,021). Kesimpulan: Asupan makanan, stres, dan aktivitas fisik merupakan faktor gaya hidup yang sangat berperan terhadap risiko hipertensi pada wanita menopause. Abstract

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Section: Pendahuluanunclassified

“…Tingkat tekanan darah pada klimakterium yang tergantung pada usia menopause dan durasi periode menopause, menunjukkan bahwa defisiensi estrogen mungkin menjadi kontributor untuk tekanan darah tinggi pada wanita lanjut usia sebesar 65 % sedangkan 35 % dapat dipengaruhi oleh faktor gaya hidup dan faktor lainnya (Izumi et al, 2007).…”

Section: Pendahuluanunclassified

Korelasi Asupan Makanan, Stres, Dan Aktivitas Fisik Dengan Hipertensi Pada Usia Menopause

Yulistina

Deliana

Rustiana

2017

UJPH

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“…18,19 Both early onset of menopause and a long postmenopausal period are associated with higher blood pressure levels. 20 Moreover, hypoestrogenemic premenopausal women diagnosed with the polycystic ovary syndrome and menstrual irregularities because of ovarian failure are at a higher risk of developing hypertension, coronary artery disease, and adverse cardiovascular events and experience menopause at an earlier age than healthy controls. 21 Interestingly, a recent report indicates that physiological 17␤-estradiol treatment in patients with premature ovarian failure results in significant reductions in blood pressure, whereas no effects on blood pressure were observed using synthetic ethinylestradiol.…”

Section: Blood Pressure and Endogenous Estrogensmentioning

confidence: 99%

mentioning

confidence: 99%

Postmenopausal Hypertension

2009

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H ypertension in women is often undiagnosed or inadequately treated, especially after menopause when cardiovascular risk increases. In premenopausal women, endogenous estrogens maintain vasodilation and thus contribute to blood pressure control. Aging and the loss of endogenous estrogen production after menopause are accompanied by increases in blood pressure, contributing to the high prevalence of hypertension in older women. Currently, Ϸ75% of postmenopausal women in the United States are hypertensive. The high prevalence of obesity, the lack of regular physical exercise, and dietary salt are important factors contributing to and aggravating postmenopausal hypertension. In view of the ongoing population aging throughout the world, diagnosis and treatment of hypertension in postmenopausal women are important to reduce the excess burden of associated cardiovascular disease and to improve outcomes of potentially fatal complications such as stroke and myocardial infarction. This article discusses current knowledge about the mechanisms and therapeutic issues related to postmenopausal hypertension. Hypertension: Important Determinant of Cardiovascular Risk in WomenMore than 25% of the female adult world population is hypertensive. 1 Elevations in blood pressure in women are related to cardiovascular risk (Figure, panel A), 2,3 with the prevalence of hypertension being particularly high among women aged Ն60 years. 1 In the United States, Ϸ75% of postmenopausal women are hypertensive. 4 Hypertension is often accompanied by other cardiovascular risk factors, eg, obesity, dyslipidemia, and diabetes mellitus. 5 It is noteworthy that the prevalence of hypertension-related cardiovascular complications is greater in postmenopausal women than in age-matched men. 6 Indeed, these complications represent the leading cause of death in women. 6 Clinical studies have documented beneficial effects of antihypertensive therapy on cardiovascular outcome, 5 even in patients Ն80 years of age. 7 Overall recognition, control, and treatment of hypertension in postmenopausal women are still poor in primary care, and hypertension is often not being treated aggressively enough. 4,8 -10 Thus, further improvements of medical and public health measures, awareness of patients and physicians, and improved information policies are needed. Blood Pressure and Endogenous Estrogens: Role of MenopausePrior to menopause, blood pressure is lower in women compared with age-matched men. 11,12 During the menstrual cycle, blood pressure levels are inversely related to circulating estrogen concentrations and lower when 17␤-estradiol levels peak, 12 reflecting the vasodilator activity of endogenous 17␤-estradiol. 13 Similarly, increases of endogenous estrogen production during pregnancy contribute to maintenance of normotension despite marked increases in plasma volume and cardiac output. 12,14 The first decade after menopause is accompanied by an increase in blood pressure ( Figure, panel B). 11,15 In the seventh decade of life, the prevalence of hypertension...

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“…150 Cross-sectional studies indicate that menopause increases the risk of hypertension by twofold, even after adjusting for factors, such as age and BMI. 151 Both early onset of menopause and a long postmenopausal period are associated with higher blood pressure levels. 152 Moreover, hypoestrogenemic premenopausal women diagnosed with polycystic ovary syndrome and menstrual irregularities because of ovarian failure are at a higher risk of developing hypertension, CAD, and adverse CV events and experience menopause at an earlier age than healthy controls.…”

Section: Blood Pressure and Endogenous Estrogensmentioning

confidence: 99%

Postmenopausal Status as Independent Risk Factor for Metabolic Syndrome

Osman¹,

Bokhari²,

Fadlalla³

2016

JSAFOMS

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Metabolic syndrome (MS), a cluster of metabolic and cardiovascular (CV) disorders, is typically characterized by abdominal obesity, insulin resistance, hyperglycemia, atherogenic dyslipidemia, and hypertension. Various studies throughout the world have documented higher prevalence of MS and CV risk factors in postmenopausal women. The aim of the present review is to discuss the potential pathophysiologic mechanisms underlying the relationship between menopause and MS.

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Effect of Age at Menopause on Blood Pressure in Postmenopausal Women

Cited by 69 publications

References 22 publications

Korelasi Asupan Makanan, Stres, Dan Aktivitas Fisik Dengan Hipertensi Pada Usia Menopause

Korelasi Asupan Makanan, Stres, Dan Aktivitas Fisik Dengan Hipertensi Pada Usia Menopause

Postmenopausal Hypertension

Postmenopausal Status as Independent Risk Factor for Metabolic Syndrome

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