Effect of Aging on Corneal Biomechanical Parameters Using the Ocular Response Analyzer

Kamiya, Kazutaka; Shimizu, Kimiya; Ohmoto, Fumiko

doi:10.3928/1081597x-20090917-10

Cited by 125 publications

(95 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, to avoid any discrepancies in our study, the utmost care was taken in selecting the age and sex distribution of the groups. The age-related increase in corneal stiffness may cause a decrease in the corneal capacities of elastic resistance and energy absorption (10). CH was found to be correlated with optic nerve surface incompliance related to intermittent increases in IOP in glaucoma subjects (13).…”

Section: Discussionmentioning

confidence: 91%

“…Nevertheless, they could not find any correlation between CCT and age, and they pointed out that age-related decreases in CH and CRF might have been associated with structural changes in collagen crosslinking (10).…”

Section: Discussionmentioning

confidence: 93%

“…We determined a significant negative correlation between age and CH and CRF, which might be caused by age-related corneal stiffness and a decrease in corneal elastic behavior. While Kamiya et al (11) and Kirwan et al (12) found no age-related differences in CH in 86 adults and 42 children, respectively, some other reports support a decrease in CH due to aging (6,(8)(9)(10). These different results might be caused by the number and demography of the subjects.…”

Section: Discussionmentioning

confidence: 94%

“…The age-related increase in corneal stiffness by increased collagen cross-linking may cause changes in corneal biomechanical parameters (6)(7)(8)(9)(10). In this study, we investigated these changes in a healthy Turkish population.…”

Section: Discussionmentioning

confidence: 99%

“…Kamiya et al (10,11) reported in their studies that CCT was the most important factor affecting corneal biomechanics. Nevertheless, they could not find any correlation between CCT and age, and they pointed out that age-related decreases in CH and CRF might have been associated with structural changes in collagen crosslinking (10).…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Age-related changes in biomechanical parameters of the cornea and intraocular pressure in a healthy Turkish population

Şen¹,

Elgin²,

Yüksekkaya³

et al. 2014

Turk J Med Sci

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Age-related changes in biomechanical parameters of the cornea and intraocular pressure in a healthy Turkish population

Şen¹,

Elgin²,

Yüksekkaya³

et al. 2014

Turk J Med Sci

View full text Add to dashboard Cite

Comparison of Ocular Response Analyzer Parameters in Chinese Subjects With Primary Angle-Closure and Primary Open-Angle Glaucoma

Narayanaswamy

Su²,

Baskaran³

et al. 2011

Arch Ophthalmol

View full text Add to dashboard Cite

Objectives: To evaluate corneal hysteresis (CH) and intraocular pressure (IOP) measured by the Ocular Response Analyzer in Chinese subjects with primary angleclosure glaucoma (PACG), assess their relationship with Goldmann applanation tonometry (GAT) measurements, and compare this with subjects with primary openangle glaucoma (POAG) and normal controls. Methods: In this prospective observational study, consecutive subjects with PACG and POAG without prior intraocular surgery were enrolled from glaucoma clinics. Normal subjects were recruited from an ongoing population-based study. One eye of each subject underwent standardized ocular examination and IOP measurement by GAT and the Ocular Response Analyzer. Corneal hysteresis and cornealcompensated IOP were compared between groups. Results: Of the 443 subjects recruited, 131 had PACG, 162 had POAG, and 150 were normal. Corneal hyster-esis was lower in PACG (9.1 mm Hg; 95% confidence interval [CI], 8.7 to 9.4 mm Hg) and POAG (9.5 mm Hg; 95% CI, 9.2 to 9.5 mm Hg) eyes compared with control eyes (10.4 mm Hg; 95% CI, 10.1 to 10.6 mm Hg; PϽ.001 for both), with no difference (P =.16) in CH found between PACG and POAG eyes. After adjusting for age, sex, and IOP measurement by GAT, CH persisted to be lower only in eyes with PACG in comparison with control eyes (9.4 vs 10.1 mm Hg; P=.006). Eyes with POAG had lower CH than control eyes but the difference was not statistically significant (9.6 vs 10.1 mm Hg; P=.06). Conclusions: Corneal hysteresis was lower in eyes with glaucoma. After adjusting for age, sex, and IOP measurement by GAT, a persistently lower hysteresis was noted in eyes with PACG compared with other groups.

show abstract

Increased Corneal Hysteresis After Corneal Collagen Crosslinking

et al. 2014

View full text Add to dashboard Cite

show abstract

Effect of Aging on Corneal Biomechanical Parameters Using the Ocular Response Analyzer

Cited by 125 publications

References 43 publications

Age-related changes in biomechanical parameters of the cornea and intraocular pressure in a healthy Turkish population

Age-related changes in biomechanical parameters of the cornea and intraocular pressure in a healthy Turkish population

Comparison of Ocular Response Analyzer Parameters in Chinese Subjects With Primary Angle-Closure and Primary Open-Angle Glaucoma

Increased Corneal Hysteresis After Corneal Collagen Crosslinking

Contact Info

Product

Resources

About