This paper reports the effect of Hot Isostatic Pressing (HIPing) on the porosity, microstructure and mechanical properties of Laser Powder Bed Fusion (LPBF) IN625 structures built at a higher layer thickness of 100 µm. It is observed that the process-induced pores/voids of volume fraction (V f ) 0.43% in as-built IN625 structures are reduced signi cantly to ~ 0.01% after HIPing treatment. The microstructure is changed from ne columnar dendrites to coarse equiaxed dendrites. The microstructural analysis of as-built structures reveals the presence of cellular/ dendritic growth along with elemental segregation of Nb, Si and C and precipitation of Nb-rich carbides. Whereas, coarse recrystallized microstructure along with elemental segregation of Si and precipitation of Nb, Mo and Cr rich carbides are observed in Hot Isostatic Pressed (HIPed) samples. HIPed structures exhibit lower tensile s trength, higher ductility, and lower anisotropy as compared to LPBF built structures. There is a reduction in the Vickers micro-hardness of IN625 samples after HIPing and the values are observed to be similar to their conventional counterparts. Further, an increase in the energy storage capacity of the material is observed after HIPing treatment through Automated Ball Indentation (ABI ® ) studies. The study paves a way to develop ~100% dense, defect-free and isotropic engineering components using LPBF.