Effect of COVID 19 Lockdown on glycemic parameters in people with type 2 diabetes

Abstract

Coronavirus disease (COVID-19) is an infectious disease caused by the newly discovered SARS-COV-2. Older people and people with pre-existing medical conditions, such as diabetes and obesity, appear to have the worst outcomes with the COVID-19 virus. In response to the COVID-19 pandemic, many countries enforced stringent lockdowns to prevent the spread of the disease. India had a lockdown of 68 days between 21st March and 31st May 2020. In this background, we undertook this study to assess the effect of the lockdown on the glycemic status and weight of people with diabetes, which was indirectly an opportunity to assess the self-care practices of people with diabetes. Material and Methods: The subjects included in the study were people with type 2 diabetes identified from electronic medical records who had attended the Jai Clinic and Diabetes Care Centre in Lucknow and were tested for HbA1c between 20th Feb 2020 and 20th March 2020. A total of 313 people with diabetes were identified meeting the inclusion criteria, out of which 171 were females and 142 were males. They were again tested for HbA1c between 1st June 2020 and 1st July 2020 after lockdown. Their pre- and post-lockdown HbA1c and weight were analyzed statistically. Results: HbA1c was increased in 195 patients, which was statistically significant. A total of 151 patients had an increase in weight compared to their prelockdown weights, but it was not statistically significant. Furthermore, an increase in weight correlated with an increase in HbA1c and a decrease in weight correlated with a decrease in HbA1c. Both were statistically significant. Conclusion: Optimum diabetes control and adherence to good self-care practices is the need of hour, and contingency plans for medicines and diabetes care supplies are of utmost importance in these testing times.

Interaction between Lifestyle Changes and PNPLA3 Genotype in NAFLD Patients during the COVID-19 Lockdown

“…In addition, high rates of reduced glycemic control and transaminases derangement were observed after lockdown in patients who increased their weight. Indeed, an impairment in glucose control during the COVID-19 pandemic was already reported in diabetic patients, and, similar to our data, it was caused by a change in diet and physical activity [ 29 , 30 , 31 , 64 ]. Conversely, no data are available in the literature on the worsening in transaminases after the COVID-19 lockdown, particularly in NAFLD patients.…”

Obesity and weight change during the COVID‐19 pandemic in children and adults: A systematic review and meta‐analysis

“…As described in Figure 1, a total of 20,955 articles were identified from the search, and after the removal of 7322 duplicates, 13,633 articles were screened for title and abstract. A full‐text screening was conducted on 296 articles, and 74 met the final inclusion and exclusion criteria and were included in the review 39–112 . Table 1 summarizes the study characteristics.…”

Neuro-ophthalmological manifestations of diabetes mellitus during COVID-19-related lockdown in India

“…Self–blood glucose monitoring should be encouraged. [ 33 ] Weight gain is an important determinant for the development or worsening of metabolic disorders. [ 33 34 ] Exercises which can be done at home such as skipping should be prescribed and encouraged for weight management.…”

“…[ 33 ] Weight gain is an important determinant for the development or worsening of metabolic disorders. [ 33 34 ] Exercises which can be done at home such as skipping should be prescribed and encouraged for weight management. Stocking of medicines and glucose testing supplies can tackle shortage of supplies.…”

“…Teleconsultation services should be strengthened to allow continuum of care and help in triaging patients. [ 33 ]…”