Effect of dietary supplemental ascorbic acid and folic acid on the growth performance, redox status, and immune status of broiler chickens under heat stress

Gouda, Ahmed; Amer, Shimaa A.; Gabr, Sherin; Tolba, Samar A.

doi:10.1007/s11250-020-02316-4

Cited by 61 publications

(57 citation statements)

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“…Several studies reported an improved efficiency in broiler chickens' performance by the dietary supplementation of vitamin C [49][50][51][52]. Gouda, et al [31] reported improvement in the growth performance, insulin growth factor 1, and thyroid hormone levels of the broilers by supplementing the diet with vitamin C (200 mg/kg) alone or along with folic acid (1.5 mg/kg). Sahin and Kucuk [53] stated that supplementation with 200 mg/kg diet of vitamin C, and not 100 mg/kg diet, resulted in increased FI, BW, and feed efficiency of Japanese quails.…”

Section: Discussionmentioning

confidence: 99%

“…A significant decrease was observed in the MDA level in the muscles of birds fed diets supplemented with safflower oil and/or vitamin C. Ascorbate is involved in the regeneration of reduced glutathione from the oxidative form in the cytoplasm; it also aids in the regeneration of tocopherol through a non-enzymatic reaction [71]. Gouda, et al [31] demonstrated an improved total antioxidant capacity, catalase activity, and SOD activity of broiler chickens under heat stress when they were fed a diet supplemented with vitamin C (200 mg/kg) alone or in combination with folic acid (1.5 mg/kg).…”

Section: Discussionmentioning

confidence: 99%

“…The rejuvenated vitamin E molecule works as an antioxidant again or it is stored [29]. Thus, dietary vitamin C improves the antioxidant status of chicken tissues [30,31]. Vitamin C plays a significant role in interacting with all types of aggressive oxygen molecules under essentially inactive radical formation and transferring the radical equivalent from the fatty stages to the water molecules [32,33].…”

Section: Introductionmentioning

confidence: 99%

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Changes in the growth, ileal digestibility, intestinal histology, behavior, fatty acid composition of the breast muscles, and blood biochemical parameters of broiler chickens by dietary inclusion of safflower oil and vitamin C

et al. 2021

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Background The effects of safflower oil and vitamin C (Vit. C) inclusion in broiler chicken diets on the growth performance, apparent ileal digestibility coefficient “AID%” of amino acids, intestinal histology, behavior, carcass traits, fatty acid composition of the breast muscle, antioxidant and immune status for a 35-day feeding period were evaluated. A total of 300 three-day-old Ross chicks (58.25 g ± 0.19) were randomly allotted in a 2 × 3 factorial design consisting of two levels of vitamin C (0 and 400 mg/kg diet) and three levels of safflower oil (0, 5, and 10 g/kg diet). Results An increase in the final body weight, total body weight gain, total feed intake, and the relative growth rate (P < 0.05) were reported by safflower oil and vitamin C inclusion. Dietary supplementation of safflower oil and vitamin C had a positive effect (P < 0.05) on the ingestive, resting, and feather preening behavior. Vitamin C supplementation increased (P < 0.05) the AID% of lysine, threonine, tryptophan, arginine, and valine. Safflower inclusion (10 g/kg) increased (P < 0.05) the AID% of methionine and isoleucine. Safflower oil inclusion increased (P < 0.05) the levels of stearic acid, linoleic acid, saturated fatty acids, and omega-3 fatty acids (ω-3) in the breast muscle. In contrast, the supplementation of only 10 g of safflower oil/kg diet increased (P = 0.01) the omega-3/omega-6 (ω-3/ω-6) fatty acids ratio. Vit. C supplementation increased (P < 0.05) the CAT serum levels, SOD, and GSH enzymes. Dietary supplementation of safflower oil and vitamin C improved the intestinal histology. They increased the villous height and width, crypt depth, villous height/crypt depth ratio, mucosal thickness, goblet cell count, and intra-epithelium lymphocytic lick cell infiltrations. The serum levels of IgA and complement C3 were increased (P < 0.01) by Vit. C supplementation and prominent in the 400 vit. C + 10 safflower Oil group. Conclusion A dietary combination of safflower oil and vitamin C resulted in improved growth rate, amino acids AID%, intestinal histology, welfare, immune and antioxidant status of birds, and obtaining ω-3 and linoleic acid-enriched breast muscles. The best inclusion level was 400 vit. C + 10 safflower Oil.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Changes in the growth, ileal digestibility, intestinal histology, behavior, fatty acid composition of the breast muscles, and blood biochemical parameters of broiler chickens by dietary inclusion of safflower oil and vitamin C

et al. 2021

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“…With the recent ban and restrictions of using antibiotics as growth promoters, many feed supplements are widely added in poultry feeds as alternative growth promoters, such as prebiotics, phytobiotics, probiotics, organic acids, and enzymes [ 24 , 34 , 35 , 36 , 37 , 38 ]. Recently, MCFAs have received more consideration because of their potential antimicrobial effects.…”

Section: Discussionmentioning

confidence: 99%

Effect of Dietary Medium-Chain α-Monoglycerides on the Growth Performance, Intestinal Histomorphology, Amino Acid Digestibility, and Broiler Chickens’ Blood Biochemical Parameters

Amer

A-Nasser

Al-Khalaifah

et al. 2020

Animals

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This trial was conducted to assess the impact of medium-chain α-monoglycerides, glycerol monolaurate (GML) supplementation on the growth performance, apparent ileal digestibility coefficient (AID%) of amino acids, intestinal histomorphology, and blood biochemical parameters of broiler chickens. Three-day-old chicks (76.82 g ± 0.40, n = 200) were haphazardly allocated to four experimental groups with five replicates for each (10 chicks/replicate). The treatments consisted of basal diets supplemented with four glycerol monolaurate levels; 0, 1, 3, or 5 g kg−1 (GML0, GML1, GML3, and GML5, respectively). Growth performance was determined at three periods (starter, grower, and finisher). Dietary GML had no significant effect on the growth performance parameters (body weight, weight gain, and feed conversion ratio) through all the experimental periods. GML1 diet increased the AID% of leucine and decreased the AID% of arginine. GML1 diet increased the duodenal and jejunal villous height and the jejunal muscle thickness. GML3 and GML5 diets increased the goblet cell count in the duodenum. GML supplementation increased the serum level of high density lipoprotein (HDL)-cholesterol. GML5 diet increased the serum levels of IgM and interleukin 10 compared to the control group. We could conclude that dietary supplementation of glycerol monolaurate can supplement broiler chicken diets up to 5 g kg−1 to enhance the immune status and intestinal histomorphology of birds with no improving effect on growth performance.

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“…Feed additives are widely used in the poultry industry to support animal production traits and maintain their good health (1)(2)(3)(4)(5)(6)(7)(8). Sub-therapeutic uses of antibiotics as growth promoters in poultry feed have caused controversies, such as drug resistance and residues in the meat (9).…”

Section: Introductionmentioning

confidence: 99%

Effects of Phenolic-Rich Onion (Allium cepa L.) Extract on the Growth Performance, Behavior, Intestinal Histology, Amino Acid Digestibility, Antioxidant Activity, and the Immune Status of Broiler Chickens

et al. 2020

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Effect of dietary supplemental ascorbic acid and folic acid on the growth performance, redox status, and immune status of broiler chickens under heat stress

Cited by 61 publications

References 58 publications

Changes in the growth, ileal digestibility, intestinal histology, behavior, fatty acid composition of the breast muscles, and blood biochemical parameters of broiler chickens by dietary inclusion of safflower oil and vitamin C

Changes in the growth, ileal digestibility, intestinal histology, behavior, fatty acid composition of the breast muscles, and blood biochemical parameters of broiler chickens by dietary inclusion of safflower oil and vitamin C

Effect of Dietary Medium-Chain α-Monoglycerides on the Growth Performance, Intestinal Histomorphology, Amino Acid Digestibility, and Broiler Chickens’ Blood Biochemical Parameters

Effects of Phenolic-Rich Onion (Allium cepa L.) Extract on the Growth Performance, Behavior, Intestinal Histology, Amino Acid Digestibility, Antioxidant Activity, and the Immune Status of Broiler Chickens

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