Effect of digluconate chlorhexidine on bond strength between dental adhesive systems and dentin: A systematic review

Abstract

Aim:This study aimed to systematically review the literature for the effect of digluconate chlorhexidine (CHX) on bond strength between dental adhesive systems and dentin of composite restorations.Materials and Methods:The electronic databases that were searched to identify manuscripts for inclusion were Medline via PubMed and Google search engine. The search strategies were computer search of the database and review of reference lists of the related articles. Search words/terms were as follows: (digluconate chlorhexidine*) AND (dentin* OR adhesive system* OR bond strength*).Results:Bond strength reduction after CHX treatments varied among the studies, ranging 0-84.9%. In most of the studies, pretreatment CHX exhibited lower bond strength reduction than the control experimental groups. Researchers who previously investigated the effect of CHX on the bond strength of dental adhesive systems on dentin have reported contrary results, which may be attributed to different experimental methods, different designs of the experiments, and different materials investigated.Conclusions:Further investigations, in particular clinical studies, would be necessary to clarify the effect of CHX on the longevity of dentin bonds.

Bonding efficiency and durability: current possibilities

“…74,85,86,87 The use of 2% CHX solution as an effective and nonspecific protease inhibitor primer, after acid-etching, is attractive from a clinical point of view, since it is already used in other oral health situations as an antimicrobial agent. 88 Compared to control, aged CHX-treated dentin relates to higher bond strength values 73,74,77,78,79,80,89,90,91,92 which are interestingly equivalent to each other in most of the immediate evaluations. 93 Especially when two step etch-and-rinse adhesives are used, reduction of bond strength values for conventionally treated dentin over one to two years is of approximately 50%; when CHX is applied after acid etching, total reduction is around 20% 72 to 84.9%.…”

“…93 Especially when two step etch-and-rinse adhesives are used, reduction of bond strength values for conventionally treated dentin over one to two years is of approximately 50%; when CHX is applied after acid etching, total reduction is around 20% 72 to 84.9%. 88 Even though the presence of carious-affected dentin, as well as artificially eroded dentin, relates to inferior bond strength values, 53,94,95 CHX can preserve adhesive interface stablished by two-step etch-and-rinse adhesives, although not indefinitely. 77,96,97,98,99 Higher bond strength durability of a two-step self-etch adhesive over 2-year aging in artificial saliva and under simulated intrapulpal pressure was also described in the literature when caries-affected dentin was pretreated with CHX.…”

“…115,119 Tough medium-term randomized clinical trials (18-36 months) does not show significant beneficial results from incorporating CHX to adhesive treatment of dentin. 121,122,123 Loguercio et al, 105 incite researchers to evaluate the only one proven clinically and easy to adopt strategy 88 after long-term follow-ups, when the benefits of CHX would possibly turn out to be detectable.…”

Effects and Effectiveness of Cavity Disinfectants in Operative Dentistry: A Literature Review

“…15 Presently, CHX is one of the most widely used antimicrobial agents in oral health 16 and is considered the "gold standard" of oral antiseptics. 17,18 Different concentrations and forms of CHX are available: 0.12 to 0.2% mouthrinses, 2% cavity-cleaning solutions, and 0.5 to 1% gels.…”

Effect of pretreatment with different MMP inhibitors on shear bond strength of composite to primary teeth dentin after six months of aging

“…Representative images from visualization of cut sections of sheared dentinal surfaces by SEM.Images I (CHX group) and II (control group).C:Composite,D:DentinDiscussionNumerous factors could affect the bond strength of adhesive agents. Mechanical stresses induced by chewing forces, temperature and pH fluctuations of the oral cavity, water sorption, resin shrinkage, and enzymatic action of MMPs are amid factors that can influence the bond integrity to diverse extents[13].…”