Effect of extracorporeal shock waves on inflammation and angiogenesis of integumentary tissue in obese individuals: stimulating repair and regeneration

Modena, Débora Aparecida Oliveira; Soares, Ciro Dantas; Cândido, Elaine Cristina; Chaim, Felipe David Mendonça; Cazzo, Everton; Chaim, Élinton Adami

doi:10.1007/s10103-021-03387-x

Cited by 13 publications

(10 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ESWT can also have a significant impact on the neural tissue repairment and regeneration process by increasing local blood circulation, as ESWT can mechanically lead to vascular endothelial shear stress, generating a frictional force on the surface of the vascular epithelium ( 124 ), which can potentially lead to the recruitment or migration of endothelial cells (ECs). Studies of human umbilical vein endothelial cells (HUVECs) treated with ESWT ( 125 ) suggested that vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS) are two essential angiogenesis mediators for ESWT-induced ECs recruitment and migration.…”

Section: Cellular and Molecular Mechanismmentioning

confidence: 99%

Application of extracorporeal shock wave therapy in nervous system diseases: A review

Guo

Hai

2022

Front. Neurol.

View full text Add to dashboard Cite

Neurological disorders are one of the leading causes of morbidity and mortality worldwide, and their therapeutic options remain limited. Recent animal and clinical studies have shown the potential of extracorporeal shock wave therapy (ESWT) as an innovative, safe, and cost-effective option to treat neurological disorders. Moreover, the cellular and molecular mechanism of ESWT has been proposed to better understand the regeneration and repairment of neurological disorders by ESWT. In this review, we discuss the principles of ESWT, the animal and clinical studies involving the use of ESWT to treat central and peripheral nervous system diseases, and the proposed cellular and molecular mechanism of ESWT. We also discuss the challenges encountered when applying ESWT to the human brain and spinal cord and the new potential applications of ESWT in treating neurological disorders.

show abstract

Section: Cellular and Molecular Mechanismmentioning

confidence: 99%

Application of extracorporeal shock wave therapy in nervous system diseases: A review

Guo

Hai

2022

Front. Neurol.

View full text Add to dashboard Cite

show abstract

“…A number of studies have shown that ESWT exerts positive effects on cell proliferation and angiogenesis [ 54 – 57 ]. Vascular endothelial growth factor (VEGF) was significantly increased in tissue samples of ESWT-treated rat models [ 58 ].…”

Section: Discussionmentioning

confidence: 99%

Global trends in research on extracorporeal shock wave therapy (ESWT) from 2000 to 2021

Zhang

2023

BMC Musculoskelet Disord

View full text Add to dashboard Cite

Background This study intended to analyze the application of extracorporeal shock wave therapy in medicine and to evaluate the quality of related literature. Methods All publications were extracted from 2000 to 2021 from the Web of Science Core Collection (WoSCC). The literature characteristics were depicted by VOSviewer (version 1.6.15) and the online bibliometric website (http://bibliometric.com/). The future trends and hotspots were conducted by Bibliographic Item Co-occurrence Matrix Builder (version 2.0) and gCLUTO software. Results We analyzed 1774 articles corresponding to the criteria for ESWT publications from 2000 to 2021. Most studies were conducted within the United States and China which besides have the most cooperation. The most published research institutions are Chang Gung University, Kaohsiung Chang Gung Memorial Hospital, and Kaohsiung Medical University. Six research hotspots were identified by keyword clustering analysis: Cluster0: The effects of ESWT on muscle spasticity; Cluster1: The application of ESWT in osteoarthritis (OA); Cluster2: Therapeutic effect of ESWT on tendon diseases; Cluster3: Early application of ESWT/ESWL in urolithiasis; Cluster4: The Role of angiogenesis in ESWT and the efficiency of ESWT for penile disease; Cluster5: The Special value of radial extracorporeal shock wave therapy (rESWT). Conclusions A comprehensive and systematic bibliometric analysis of ESWT was conducted in our study. We identified six ESWT-related research hotspots and predicted future research trends. With the gradual increase of research on ESWT, we find that ESWT is used more and more extensively, such in musculoskeletal disease, bone delay union, neurological injury, andrology disorders, lymphedema, and so on. In addition, the mechanism is not destructive damage, as initially thought, but a restorative treatment. Furthermore, delayed union, cellulite, burn, and diabetic foot ulcers may be the future direction of scientific study.

show abstract

“…In addition, a higher ESWT pulse was associated with an improved recovery effect ( 42 ). Furthermore, Modena et al ( 43 ) suggested that ESWT could activate angiogenesis by upregulating the angiogenesis markers (CD105 and VEGF) ( Fig. 1 ).…”

Section: Mechanisms Of Eswt In Treating Patients With Psfnmentioning

confidence: 98%

Extracorporeal shock wave treatment for post‑surgical fracture nonunion: Insight into its mechanism, efficacy, safety and prognostic factors (Review)

Wang

Shi

2023

Exp Ther Med

View full text Add to dashboard Cite

Post-surgical fracture nonunion (PSFN) represents the failure to achieve cortical continuity at radiological examination after an orthopedic operation, which causes a considerable disease burden in patients with fractures. As one of the traditional treatment modalities, surgical therapy is associated with a high fracture union rate; however, post-surgical complications are not negligible. Therefore, less invasive therapies are needed to improve the prognosis of patients with PSFN. Extracorporeal shock wave treatment (ESWT) is a noninvasive method that presents a similar efficacy profile and favorable safety profile compared with surgical treatment. However, the application and detailed mechanism of ESWT in patients with PSFN remain unclear. The present review focuses on the mechanism, efficacy, safety and prognostic factors of ESWT in patients with PSFN, aiming to provide a theoretical basis for its application and improve the prognosis of these patients.

show abstract

Effect of extracorporeal shock waves on inflammation and angiogenesis of integumentary tissue in obese individuals: stimulating repair and regeneration

Cited by 13 publications

References 34 publications

Application of extracorporeal shock wave therapy in nervous system diseases: A review

Application of extracorporeal shock wave therapy in nervous system diseases: A review

Global trends in research on extracorporeal shock wave therapy (ESWT) from 2000 to 2021

Extracorporeal shock wave treatment for post‑surgical fracture nonunion: Insight into its mechanism, efficacy, safety and prognostic factors (Review)

Contact Info

Product

Resources

About